Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hiroko Nomaguchi"'
Publikováno v:
Vaccine. 19:1906-1910
The components of Ag85 (Ag85A, Ag85B, and Ag85C) are putative protective antigen candidates against mycobacterial infection. A recombinant Mycobacterium bovis Bacillus Calmette-Guérin (rBCG) over-producing Ag85A, Ag85B, and MPB51 (rBCG/BA51) was con
Publikováno v:
Vaccine. 18:1294-1297
Immunization of mice with recombinant Mycobacterium bovis Bacillus Calmette-Guérin (rBCG) which over-produces a putative protective antigen candidate, the A component of antigen 85 complex (Ag85A), reduced the multiplication of Mycobacterium leprae
Publikováno v:
Vaccine. 18:795-798
The proteins in culture filtrate derived from Bacillus Calmette–Guerin (BCG) were examined for protection against infection by Mycobacterium leprae. Immunization with the major secreted proteins, antigen 85 complex (Ag 85) A, B and C, induced effec
Autor:
Osamu Kohashi, Hiroko Nomaguchi, M. Azizul Haque, Osamu Tokunaga, Shigeyasu Inada, Shin Yoshino
Publikováno v:
European Journal of Immunology. 26:2650-2656
Oral administration of mycobacterial 65-kDa heat shock protein (HSP) given daily for 5 days prior to immunization with Mycobacterium tuberculosis (Mt) suppressed the development of adjuvant arthritis (AA) in rats. AA was significantly suppressed by 3
Autor:
Akira Shimada, Tomohiro Kasatani, Yukako Ozawa, Akira Kasuga, Taro Maruyama, Hiroko Nomaguchi, Takao Saruta, Izumi Takei, Junichi Miyazaki
Publikováno v:
Journal of Autoimmunity. 9:517-524
Autoantibodies against heat shock protein (hsp) 60 have been reported to be detected in sera of non-obese diabetic mice, in an experimental model of IDDM. However, there are only a few studies which have examined IDDM patients for antibodies against
Publikováno v:
Japanese journal of leprosy. 65:113-120
Neurotropism is one of the most important characteristics of Mycobacterium leprae (M. leprae). It is believed that nerve damage of leprosy is caused by various immune mechanisms 1), and so called "autoimmune reaction" is suspected to have one of the
Autor:
Hiroko Nomaguchi, Kazuhide Kobayashi, Takeshi Yamada, Hitoshi Hotokezaka, Hideaki Hayashida, Naoya Ohara
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1219:175-178
The homologue of groESL from Porphyromonas gingivalis was cloned and sequenced. Nucleotide sequencing suggested an operon containing two open reading frames (ORFs) homologous to groESL operon of Escherichia coli. The upstream ORF consisted of 267 bp
Autor:
Hiroko Nomaguchi, Akira Shimada, Taro Maruyama, Takao Saruta, Tomohiro Kasatani, Izumi Takei, Akira Kasuga, Kenji Watanabe
Publikováno v:
Diabetes Research and Clinical Practice. 21:25-29
We have investigated whether antibodies to heat shock protein (hsp) 65 are present in sera from patients with insulin-dependent diabetes mellitus by using Mycobacterium leprae hsp65. Fifty-two sera from patients with IDDM, 36 from patients with uncla
Publikováno v:
Ensho. 13:553-559
The involvement of heat shock protein (hsp) in the pathogenesis of RA has been implied, however, the precise mechanism is still unknown. We analyzed the individual data of antibody level to r-hsp 65 in comparison with the level to the crude mycobacte
Autor:
Masanori Kai, Norihisa Ishii, Yumi Maeda, Ikuya Yano, Kazuo Kobayashi, Hiroko Nomaguchi, Tetsu Mukai, Yasuo Fukutomi, Toru Mori, Chiyoji Abe, Ryoji Maekura, Masahiko Makino, Seigo Kitada
Publikováno v:
FEMS microbiology letters. 272(2)
As serodiagnosis is the easiest way of diagnosing a disease, the utility of Mycobacterium leprae-derived major membrane protein-II (MMP-II), one of the immuno-dominant antigens, in the serodiagnosis of leprosy was examined. The percent positivity by