Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hiroko Nakae"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:1012-1018
Pharmacokinetic profiles of canrenoic acid (CRA) and canrenone (CR), the reversible metabolite of CRA, were studied in the rat after intraportal (pv) administration in comparison with those after intravenous (iv) administration using an interconversi
Autor:
Shozo Asada, Hiroko Nakae
Publikováno v:
Chemicalpharmaceutical bulletin. 40(3)
Proliferation of human leukemia cells, HL60, was synergistically inhibited by a combination of human interferons and azidothymidine in vitro. Combination of interferon-gamma (3000 U/ml) and azidothymidine (30 microM) inhibited cell growth by 76%, whe
Publikováno v:
Chemical and Pharmaceutical Bulletin. 33:2648-2653
Publikováno v:
YAKUGAKU ZASSHI. 103:110-118
Publikováno v:
Chemical and Pharmaceutical Bulletin. 25:427-433
The new method employed to organic anions was applied to investigate the active excretory process of organic cations from liver cells to bile canaliculi. Biliary excretion of acetyl procaineamide ethobromide (APAEB) and quinine in rats was studied af
Publikováno v:
Chemical and Pharmaceutical Bulletin. 36:4612-4618
4-Acetamidoacetophenone (Ia), 4-acetylbenzenesulfonamide (IIa) and acetohexamide (IIIa) and the respective reduced compounds, 4-substituted α-hydroxyethylphenyl derivatives, are in a reversible drug-metabolite relationship in rats. The pharmacokinet
Publikováno v:
YAKUGAKU ZASSHI. 108:1072-1080
Publikováno v:
Chemical and Pharmaceutical Bulletin. 24:886-893
The hepato-biliary transport characteristics in vivo and the uptake process by liver slices and by liver cell suspensions were studied in rats using procaineamide ethobromide, its N-acetyl compound and quinine. These organic cations were transported
Publikováno v:
Chemical and Pharmaceutical Bulletin. 37:760-765
The pharmacokinetic profiles of the hypoglycemic agent, acetohexamide (AH) and its major active metabolite, hydroxyhexamide (HH) were studied in three species of laboratory animals after intraperitoneal (ipl) administration in comparison with those a
Autor:
Hiroko Nakae, Kanji Takada, Shozo Asada, Midori Yamamoto, Koji Kuroda, Tomoko Yamamoto, Teruyoshi Yokoyama
Publikováno v:
YAKUGAKU ZASSHI. 102:196-201