Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hiroko Makihara"'
Autor:
Yuko Kawamoto, Mikiko Tada, Tetsuya Asano, Haruko Nakamura, Aoi Jitsuki-Takahashi, Hiroko Makihara, Shun Kubota, Shunta Hashiguchi, Misako Kunii, Toshio Ohshima, Yoshio Goshima, Hideyuki Takeuchi, Hiroshi Doi, Fumio Nakamura, Fumiaki Tanaka
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
In amyotrophic lateral sclerosis (ALS), neurodegeneration is characterized by distal axonopathy that begins at the distal axons, including the neuromuscular junctions, and progresses proximally in a “dying back” manner prior to the degeneration o
Externí odkaz:
https://doaj.org/article/9485f55f46a343b097fec5aaa355cf66
Autor:
Aderemi Caleb Aladeokin, Tomoko Akiyama, Ayuko Kimura, Yayoi Kimura, Aoi Takahashi-Jitsuki, Haruko Nakamura, Hiroko Makihara, Daiki Masukawa, Jun Nakabayashi, Hisashi Hirano, Fumio Nakamura, Takashi Saito, Takaomi Saido, Yoshio Goshima
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
Alzheimer’s disease (AD) is an incurable neurodegenerative disease characterized by memory loss and neurotoxic amyloid beta (Aβ) plaques accumulation. Numerous pharmacological interventions targeting Aβ plaques accumulation have failed to allevia
Externí odkaz:
https://doaj.org/article/3959496a745b4df9a2d3b2a7a1cd1a19
Autor:
Yoshiko Horie, Hiroko Makihara, Kazumasa Horikawa, Fumika Takeshige, Ai Ibuki, Toshihiko Satake, Kazunori Yasumura, Jiro Maegawa, Hideaki Mitsui, Kenichi Ohashi, Tomoko Akase
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193830 (2018)
Skin barrier function is often deficient in obese individuals, but the underlying molecular mechanisms remain unclear. This study investigated how skin structure and lipid metabolism, factors strongly associated with barrier function, differed among
Externí odkaz:
https://doaj.org/article/dea9032e257c4c8ca8e4b91fe388a79d
Autor:
Joseph T. Coyle, Richard L. Sidman, Brian T. D. Tobe, Aoi Jitsuki-Takahashi, Hiroko Makihara, Fumio Nakamura, Haruko Nakamura, Yoshio Hirayasu, Keisuke Watanabe, Naoya Yamashita, Glenn T. Konopaske, Evan Y. Snyder, Cameron D Pernia, Yoshio Goshima, Munetaka Nomoto, Reina Aoki, Yusuke Saigusa, Toshihiko Baba, Francine M. Benes, Mari Saito
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance There are no biomarkers for schizophrenia (SCZ), a disorder of dysfunctional neural networks. We demonstrate that a master regulator of cytoskeleton (“CRMP2”) and, hence, neural circuitry, may form the basis for such a biomarker beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a9bb79a052ee84bd9c78fb40d942ed
http://europepmc.org/articles/PMC8346854
http://europepmc.org/articles/PMC8346854
Autor:
Tomoko Akase, Ai Ibuki, Masahito Tsubata, Hiroshi Tomozawa, Hiroko Makihara, Yutaka Matsumoto, Moeko Hidaka, Kazumasa Horikawa, Takatoshi Ogami
Publikováno v:
Journal of Natural Medicines. 71:59-67
Obesity results from excessive energy intake and physical inactivity, and predisposes one to various diseases. One of these reasons is that enlargement of adipocytes raises the lipid metabolic abnormalities that affect various organs. The skin is one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe456649d1bc8b3c21850931ae77b93
https://doi.org/10.1007/s11418-016-1027-8
https://doi.org/10.1007/s11418-016-1027-8
Autor:
Kaoru Kinoshita, Tomoko Akase, Masahito Tsubata, Hiroko Makihara, Emi Horiguchi-Babamoto, Masatomi Ohta, Yuka Koike, Masaki Aburada, Tsutomu Shimada, Yoshio Goshima
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:1137-1143
Visceral obesity induces the onset of metabolic disorders such as insulin resistance and diabetes mellitus. Adipose tissue is considered as a potential pharmacological target for treating metabolic disorders. The fruit of Terminalia bellirica is exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3deb0f06458b86739f0f1f01bc71f2cb
https://doi.org/10.1248/bpb.b16-00064
https://doi.org/10.1248/bpb.b16-00064
Autor:
Munetaka Nomoto, Konopaske, Glenn T., Naoya Yamashita, Reina Aoki, Aoi Jitsuki-Takahashi, Haruko Nakamura, Hiroko Makihara, Mari Saito, Yusuke Saigusa, Fumio Nakamura, Keisuke Watanabe, Toshihiko Baba, Benes, Francine M., Tobe, Brian T. D., Pernia, Cameron D., Coyle, Joseph T., Sidman, Richard L., Yoshio Hirayasu, Snyder, Evan Y., Yoshio Goshima
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/3/2021, Vol. 118 Issue 31, p1-7, 7p
Autor:
Naoya Yamashita, Munetaka Nomoto, Yoshio Goshima, Aoi Jitsuki-Takahashi, Haruko Nakamura, Snyder Evan Y, Fumio Nakamura, Hiroko Makihara, Yoshio Hirayasu
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7828cdf42717aba04d301a6b36520992
https://doi.org/10.1254/jpssuppl.93.0_2-p-167
https://doi.org/10.1254/jpssuppl.93.0_2-p-167
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae52b577735c1ef266b81ff5170aedab
https://doi.org/10.1254/jpssuppl.93.0_2-p-255
https://doi.org/10.1254/jpssuppl.93.0_2-p-255
Autor:
Hisashi Hirano, Fumio Nakamura, Tomoko Akiyama, Aoi Takahashi-Jitsuki, Ayuko Kimura, Aderemi Caleb Aladeokin, Yoshio Goshima, Yayoi Kimura, Haruko Nakamura, Takashi Saito, Jun Nakabayashi, Daiki Masukawa, Takaomi C. Saido, Hiroko Makihara
Publikováno v:
Neurobiology of Disease, Vol 132, Iss, Pp-(2019)
Alzheimer’s disease (AD) is an incurable neurodegenerative disease characterized by memory loss and neurotoxic amyloid beta (Aβ) plaques accumulation. Numerous pharmacological interventions targeting Aβ plaques accumulation have failed to allevia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dc81b3abcf566e2fe3e11ffbc8b8d8
https://doi.org/10.1016/j.nbd.2019.104603
https://doi.org/10.1016/j.nbd.2019.104603