Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hiroko Komiyama"'
Autor:
Yasuko Karasawa, Hiroko Komiyama, Shigeru Yoshida, Noriko Hino, Yasuhiro Katsuura, Shiro Nakaike, Hiroaki Araki
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 4, Pp 305-312 (2003)
We investigated the effect of TTC-909, a drug preparation of the stable prostaglandin I2 analogue clinprost (isocarbacyclin methylester; methyl 5-{(1S,5S,6R,7R)-7-hydroxy-6-[(E)-(S)-3-hydroxy-1-octenyl] bicyclo[3.3.0]oct-2-en-3-yl} pentanoate) incorp
Externí odkaz:
https://doaj.org/article/7cba233616044e5ca55108378a1f7fd2
Autor:
Ayaka Kaku-Fukumoto, Noriko Hino, Hirohiko Hikichi, Dai Nozawa, Jun-ichi Karasawa, Toshio Nakamura, Emi Tatsuda, Shigeyuki Chaki, Yasumitsu Tomishima, Toshiyuki Marumo, Toshiharu Shimazaki, Makiko Kotani, Hiroko Komiyama
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:276-285
Histamine H3 receptor antagonists/inverse agonists are known to enhance the activity of histaminergic neurons in the brain, thereby promoting arousal and cognition. Here, we report the in vitro and in vivo pharmacological profiles for a newly synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf1b46a58c5f29e719fa092f8a420ec
https://doi.org/10.1124/jpet.120.000185
https://doi.org/10.1124/jpet.120.000185
Autor:
Noriko, Hino, Toshiyuki, Marumo, Makiko, Kotani, Toshiharu, Shimazaki, Ayaka, Kaku-Fukumoto, Hirohiko, Hikichi, Jun-Ichi, Karasawa, Yasumitsu, Tomishima, Hiroko, Komiyama, Emi, Tatsuda, Dai, Nozawa, Toshio, Nakamura, Shigeyuki, Chaki
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 375(2)
Histamine H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4bb83aca81af8a17a5879f4ee7f1340
https://pubmed.ncbi.nlm.nih.gov/32862143
https://pubmed.ncbi.nlm.nih.gov/32862143
Autor:
Hiroko Komiyama, Yasuko Karasawa, Hiroaki Araki, Shiro Nakaike, Noriko Hino, Shigeru Yoshida, Yasuhiro Katsuura
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 4, Pp 305-312 (2003)
We investigated the effect of TTC-909, a drug preparation of the stable prostaglandin I(2) analogue clinprost (isocarbacyclin methylester; methyl 5-[(1S,5S,6R,7R)-7-hydroxy-6-[(E)-(S)-3-hydroxy-1-octenyl] bicyclo[3.3.0]oct-2-en-3-yl] pentanoate) inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec980b20738f00312a2800a3f2219063
https://doi.org/10.1254/jphs.91.305
https://doi.org/10.1254/jphs.91.305
Autor:
Takehiko Hitomi, Yoshihiko Isobe, Hiroaki Araki, Tsunefumi Kobayashi, Shiro Nakaike, Hiroko Komiyama, Yasuko Karasawa, Shigeru Yoshida
Publikováno v:
European Journal of Pharmacology. 449:127-133
We investigated the effect of TTC-909, a preparation of the stable prostaglandin I(2) analogue clinprost (isocarbacyclin methylester; methyl 5-[(1S,5S,6R,7R)-7-hydroxy-6-[(E)-(S)-3-hydroxy-1-octenyl] bicyclo[3.3.0]oct-2-en-3-yl] pentanoate) incorpora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9fe399054e792f7f47cc5136bba76a
https://doi.org/10.1016/s0014-2999(02)01945-3
https://doi.org/10.1016/s0014-2999(02)01945-3
Autor:
Nobuo Nemoto, Shuzo Matsuda, Tatsuro Miyahara, Masa-aki Matsumoto, Koichi Ikeda, Ushio Sankawa, Toshimitsu Hayashi, Ryuichi Yamada, Hiroko Komiyama, Harumi Tonoyama
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1037-1042
Scopadulcic acid B and its structurally related compounds showed inhibitory effects on bone resorption and osteoclast formation in vitro . Scopadulciol was the most potent inhibitor among 21 compounds tested.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa63f64914e7587dd05267a0ca1a613
https://doi.org/10.1016/0960-894x(96)00173-4
https://doi.org/10.1016/0960-894x(96)00173-4
Autor:
Tatsuro Miyahara, Hiroko Komiyama, A. Miyanishi, Hiroshi Kozuka, K. Hashimoto, M. Matsumoto, K. Yokoyama, N. Kotera, F. Maruyama
Publikováno v:
Calcified Tissue International. 56:49-53
Bone-resorbing activities of 24-epi-1α-hydroxyvitamin D2 [24-epi-1α(OH)D2], 24-epi-1α,25-dihydroxyvitamin D2 [24-epi-1,25(OH)2D2], and 1α,24S,25-trihydroxyvitamin D2 [1,24S,25(OH)3D2], which might be a metabolite of 24-epi-1,25(OH)2D2, were inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6396142fc796954e8fbae0c8a919b4b6
https://doi.org/10.1007/bf00298744
https://doi.org/10.1007/bf00298744
Autor:
W. Xue-Ya, Hiroko Komiyama, A. Miyanishi, M. Nagai, Hiroshi Kozuka, M. Takata, Tatsuro Miyahara, S. Takata, K. Yokoyama, Y. Kanamoto, M. Matsumoto
Publikováno v:
Calcified Tissue International. 54:165-169
To examine an effect of lead (Pb) on the process of osteoclast-like cell formation from its progenitors, we used a mouse bone marrow culture system in which osteoclast-like multinucleated cells (MNCs) were formed in response to bone-resorbing agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9460c58f5db909f12ac8dc29d31cee65
https://doi.org/10.1007/bf00296069
https://doi.org/10.1007/bf00296069
Autor:
Hiroshi Odake, Hiroko Komiyama, Masako Yamamoto, Masakazu Takata, Toshimitsu Hayashi, Tatsuro Miyahara, Atsuko Miyanishi, Miyuki Nagai, Hiroshi Kozuka, Fumitomo Koizumi, Yusuke Ito
Publikováno v:
Toxicology. 97(1-3)
To clarify whether hypercalcemia after injection of Pb to rats is due to biological bone resorption or physicochemical mineral dissolution, the effect of lead (Pb) on release of previously incorporated 45Ca in organ culture was investigated. Pb at 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c41fe64ebbd24b6bae3016d1737d5d
https://pubmed.ncbi.nlm.nih.gov/7716786
https://pubmed.ncbi.nlm.nih.gov/7716786
Publikováno v:
Sen'i Gakkaishi. 20:52-56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccaea753751450b7d78cd5acbeb5059a
https://doi.org/10.2115/fiber.20.52
https://doi.org/10.2115/fiber.20.52