Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Hiroko Kishi"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 4, Pp 189-197 (2022)
We previously discovered that the SPC/Fyn/Rho-kinase (ROK) pathway mediates the Ca2+-sensitization of coronary arterial smooth muscle (CASM) contraction leading to vasospasm, a major cause of sudden death. Lately, we have been trying to find and deve
Externí odkaz:
https://doaj.org/article/8c948e29ce284faaa8e817a6325708a2
Autor:
Ying Zhang, Huanyu Zheng, Ming Xu, Noriko Maeda, Ryouichi Tsunedomi, Hiroko Kishi, Hiroaki Nagano, Sei Kobayashi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15980 (2023)
Metastasis is the leading cause of death in breast cancer patients due to the lack of effective therapies. Elevated levels of paxillin expression have been observed in various cancer types, with tyrosine phosphorylation shown to play a critical role
Externí odkaz:
https://doaj.org/article/cf4868a00de648739b3719641f87e5cd
Publikováno v:
Journal of Cardiovascular Pharmacology. 79:456-466
Cardiovascular diseases are the leading cause of mortality and disability worldwide. We have previously found that sphingosylphosphorylcholine (SPC) is the key molecule leading to vasospasm. We have also identified the SPC/Src family protein tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdccc4c07e7b417b5a6e6b7d2024ea9
https://doi.org/10.1097/fjc.0000000000001210
https://doi.org/10.1097/fjc.0000000000001210
Publikováno v:
Cilia: From Mechanisms to Disease-Part A ISBN: 9780443185861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7504ac7b55ba027adc5eb9cea29def00
https://doi.org/10.1016/bs.mcb.2022.07.020
https://doi.org/10.1016/bs.mcb.2022.07.020
Autor:
Kaori Koga, Tetsuhiko Go, Mikiko Aoki, Ryuji Inoue, Hiroyasu Yokomise, Aya Yamamura, Kohtaro Abe, Katsuya Hirano, Lin Hai Kurahara, Narumi Aoki-Shoi, Sei Kobayashi, Eiji Yahiro, Satoh Toru, Hiroko Kishi, Keizo Hiraishi, Zhang Bo, Kaori Ishikawa, Ying Zhang
Publikováno v:
Journal of Molecular and Cellular Cardiology. 148:50-62
Pulmonary arterial hypertension (PAH) is a multifactorial disease characterized by pulmonary arterial vasoconstriction and remodeling. Src family tyrosine kinases, including Fyn, play critical roles in vascular remodeling via the inhibition of STAT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0124da393ce7dfdf1b9d5a2303ff43c6
https://doi.org/10.1016/j.yjmcc.2020.08.013
https://doi.org/10.1016/j.yjmcc.2020.08.013
Autor:
Junko Inagaki, Makoto Mitarai, Hiroko Kishi, Katsuko Kajiya, Seiji Umemoto, Hiroshi Oda, Sei Kobayashi, Atsuko Kawamura
Publikováno v:
Current Hypertension Reviews
Background: We previously reported the nutritional characteristics and effects of the DASH-JUMP diet, which is a WASHOKU-modified DASH diet, in Japanese participants with untreated high-normal blood pressure or stage 1 hypertension. The dietary adher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dae88547f55f326f39eafe1e33b0332
http://europepmc.org/articles/PMC7499351
http://europepmc.org/articles/PMC7499351
Publikováno v:
The FASEB Journal. 35
Rho-kinase (ROK)-mediated migration of vascular smooth muscle cells plays a crucial role in cardiovascular diseases. Previously we demonstrated Fyn tyrosine kinase as an upstream molecule of ROK to mediate actin stress fiber formation that plays an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a940b3af8fa9c33b95e50ee38b7205e7
https://doi.org/10.1096/fj.202101035rr
https://doi.org/10.1096/fj.202101035rr
Publikováno v:
Journal of Smooth Muscle Research; 2023, Vol. 59, p58-66, 9p
Publikováno v:
Pharmacological Research. 134:200-211
Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer's disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a27198d27627adb746268d854305663
https://doi.org/10.1016/j.phrs.2018.06.004
https://doi.org/10.1016/j.phrs.2018.06.004
Autor:
Junko Inagaki, Sei Kobayashi, Seiji Umemoto, Hiroko Kishi, Atsuko Kawamura, Makoto Mitarai, Katsuko Kajiya, Hiroshi Oda
Publikováno v:
Current Hypertension Reviews
Background We developed a WASHOKU-modified DASH diet named DASH-JUMP. We previously reported the hypotensive effect of the DASH-JUMP diet in Japanese participants with untreated high-normal Blood Pressure (BP) or stage 1 hypertension. Objective We ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f507b21ef5674dfd2951c2e0702a842
https://doi.org/10.2174/1573402114666180405100430
https://doi.org/10.2174/1573402114666180405100430