Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hiroko Kawaguchi"'
Publikováno v:
Drug metabolism and pharmacokinetics. 42
Breast cancer resistance protein (BCRP) expressed in the blood-brain barrier plays a major role in limiting drug distribution into the central nervous system (CNS). However, functional involvement of BCRP in drug distribution into the brain and cereb
Autor:
Laura Rodriguez Amaya, Sara Garcia Torres, Araceli Martinez Ortiz, Erin Scanlon, Michelle Pruett, Hiroko Kawaguchi Warshauer
Publikováno v:
Journal of Pre-College Engineering Education Research (J-PEER)
Early exposure to engineering and mathematics career opportunities has been indicated to influence students’ decisions regarding their academic majors and career goals. This study utilized mixed methods to analyze how changes in middle school stude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7055070762ff01f3e78588978b82e9
https://docs.lib.purdue.edu/jpeer/vol8/iss2/3
https://docs.lib.purdue.edu/jpeer/vol8/iss2/3
Autor:
Masahiko, Sumi, Keijiro, Sato, Nozomu, Uematsu, Hiroko, Kawaguchi, Tsutomu, Shishido, Hiroko, Kaiume, Wataru, Takeda, Takehiko, Kirihara, Toshimitsu, Ueki, Yuki, Hiroshima, Mayumi, Ueno, Naoaki, Ichikawa, Nobuyuki, Urasawa, Hikaru, Kobayashi
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 59(2)
Vascular adverse events (VAEs) in chronic myeloid leukemia (CML) patients treated with nilotinib (NIL) has become a; however, studies on strategies to prevent VAEs remain limited. Therefore, the present study investigated VAEs in 19 CML patients trea
Autor:
Izumi Kumagai, Hiroko Kawaguchi, Ryutaro Asano, Toshio Kudo, Mitsuo Umetsu, Yu Katayose, Takeshi Nakanishi, Makoto Nakayama, Michiaki Unno, Tsuguo Kubota, Hiroki Hayashi
Publikováno v:
FEBS Journal. 279:223-233
We previously reported the construction and activity of a humanized, bispecific diabody (hEx3) that recruited T cells towards an epidermal growth factor receptor (EGFR) positive tumor. Herein, we describe the construction of a second functional, full
Autor:
Yukiko Sone, Takeshi Nakanishi, Mitsuo Umetsu, Ryutaro Asano, Izumi Kumagai, Yu Katayose, Keiko Ikoma, Michiaki Unno, Hiroko Kawaguchi, Shintaro Taki, Toshio Kudo, Hiroki Hayashi
Publikováno v:
Journal of Biological Chemistry. 285:20844-20849
We previously reported the utility for cancer immunotherapy of a humanized bispecific diabody (hEx3) that targets epidermal growth factor receptor and CD3. Here, we used dynamic and static light scattering measurements to show that the multimer fract
Autor:
Izumi Kumagai, Ryutaro Asano, Toshio Kudo, Mitsuo Umetsu, Hiroki Hayashi, Keiko Ikoma, Yu Katayose, Yuna Ishiyama, Hiroko Kawaguchi, Takeshi Nakanishi, Michiaki Unno
Publikováno v:
FEBS Journal. 277:477-487
We previously reported the use of a humanized bi-specific diabody that targets epidermal growth factor receptor and CD3 (hEx3-Db) for cancer immunotherapy. Bacterial expression can be used to express small recombinant antibodies on a large scale; how
Autor:
Mitsuo Umetsu, Yu Katayose, Ryutaro Asano, Hidesuke Fukazawa, Hiroko Kawaguchi, Michiaki Unno, Toshio Kudo, Izumi Kumagai, Takeshi Nakanishi, Hiroki Hayashi, Yasuhiro Watanabe
Publikováno v:
Journal of Biological Chemistry. 282:27659-27665
We previously reported the marked in vitro and in vivo antitumor activity of hEx3, a humanized diabody (small recombinant bispecific antibody) with epidermal growth factor receptor (EGFR) and CD3 retargeting. Here, we fabricated a tetravalent IgG-lik
Publikováno v:
Transactions of the Materials Research Society of Japan. 38:123-125
Publikováno v:
Thin Solid Films. :231-234
During the implementation of Copper (Cu) dual damascene process, Cu contamination in the process of Cu sputtering, Cu electroplating and Cu CMP has been greatly concerned. Among this Cu contamination, one by Cu CMP process and/or Cu electroplating so
Autor:
Yousuke Kunisawa, Kiyokazu Akasaka, Hiroko Kawaguchi, Naoyuki Oi, Yoshie Takahashi, Tetsuo Suyama, Yasuyuki Takakura, Mitsuru Yamamoto, Shusuke Kusano
Publikováno v:
Journal of Physical Therapy Science. 16:27-31
In 1997, the members of Japan Stroke Society presented the Japan Stroke Scale (JSS) for the acute stage, and in 2000 the Japan Stroke Scale of Motor (JSS-M) with the items of motor system required for the independence of activities of daily living (A