Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hiroko Iseoka"'
Autor:
Shigeru Miyagawa, Takuji Kawamura, Emiko Ito, Maki Takeda, Hiroko Iseoka, Junya Yokoyama, Akima Harada, Noriko Mochizuki-Oda, Yukiko Imanishi-Ochi, Junjun Li, Masao Sasai, Fumiyo Kitaoka, Masaki Nomura, Naoki Amano, Tomoko Takahashi, Hiromi Dohi, Eiichi Morii, Yoshiki Sawa
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Cell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively repair damaged heart muscle would greatly improve outcomes for patients with heart failure
Externí odkaz:
https://doaj.org/article/dfacd8d29b3c4351b45788ad52a5a5a6
Autor:
Shigeru Miyagawa, Satoshi Kainuma, Takuji Kawamura, Kota Suzuki, Yoshito Ito, Hiroko Iseoka, Emiko Ito, Maki Takeda, Masao Sasai, Noriko Mochizuki-Oda, Tomomi Shimamoto, Yukako Nitta, Hiromi Dohi, Tadashi Watabe, Yasushi Sakata, Koichi Toda, Yoshiki Sawa
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Despite major therapeutic advances, heart failure, as a non-communicable disease, remains a life-threatening disorder, with 26 million patients worldwide, causing more deaths than cancer. Therefore, novel strategies for the treatment of heart failure
Externí odkaz:
https://doaj.org/article/d2598ef6482f44ff824c95618be2a291
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract Background Transplantation of skeletal myoblast sheets is a promising strategy for the treatment of heart failure, and its therapeutic effects have already been proven in both animal disease models and clinical trials. Myoblast sheets report
Externí odkaz:
https://doaj.org/article/fb6bbb61115a4157ac4b371fbbbfcc93
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102420- (2021)
Drug efficacy assessment without using animals is important for development of cardiac fibrosis treatment. In this study, potential anti-fibrotic drugs were screened in a model of diseased myocardium using human induced pluripotent stem cell-derived
Externí odkaz:
https://doaj.org/article/5ffdadb049364facad4a765de8808128
Autor:
Keitaro Domae, Shigeru Miyagawa, Yasushi Yoshikawa, Satsuki Fukushima, Hiroki Hata, Shunsuke Saito, Satoshi Kainuma, Noriyuki Kashiyama, Hiroko Iseoka, Emiko Ito, Akima Harada, Maki Takeda, Yasushi Sakata, Koichi Toda, Kyongsun Pak, Tomomi Yamada, Yoshiki Sawa
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 13 (2021)
Background Clinical effectiveness of autologous skeletal cell‐patch implantation for nonischemic dilated cardiomyopathy has not been clearly elucidated in clinical settings. This clinical study aimed to determine the feasibility, safety, therapeuti
Externí odkaz:
https://doaj.org/article/a53220ff04544c758184aee3f0e3ad32
Autor:
Shin Yajima, MD, PhD, Shigeru Miyagawa, MD, PhD, Satsuki Fukushima, MD, PhD, Yoshiki Sakai, BSc, Hiroko Iseoka, PhD, Akima Harada, BSc, Kayako Isohashi, MD, PhD, Genki Horitsugi, BSc, Yuki Mori, PhD, Motoko Shiozaki, PhD, Hirotatsu Ohkawara, PhD, Ryoto Sakaniwa, PhD, Jun Hatazawa, MD, PhD, Yoshichika Yoshioka, PhD, Yoshiki Sawa, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 318-331 (2019)
Summary: Intravenously injected ONO-1301–containing nanoparticles (ONO-1301NPs), unlike an ONO-1301 solution, selectively accumulated in the ischemia/reperfusion (I/R)-injured myocardium of rats and contributed to the prolonged retention of ONO-130
Externí odkaz:
https://doaj.org/article/d56cb459a9fb482999992ebabc78fa26
Autor:
Shigeru Miyagawa, Satoshi Kainuma, Takuji Kawamura, Kota Suzuki, Yoshito Ito, Hiroko Iseoka, Emiko Ito, Maki Takeda, Masao Sasai, Noriko Mochizuki-Oda, Tomomi Shimamoto, Yukako Nitta, Hiromi Dohi, Tadashi Watabe, Yasushi Sakata, Koichi Toda, Yoshiki Sawa
BackgroundDespite major therapeutic advances, heart failure remains a life-threatening disorder, with 26 million patients worldwide, causing more deaths than cancer as a non-communicable disease. Therefore, novel strategies for the treatment of heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a620efc971a223fef49ef45f027a8bde
https://doi.org/10.1101/2021.12.27.21268295
https://doi.org/10.1101/2021.12.27.21268295
Publikováno v:
Circulation. 144
Background: Regenerative therapy for heart failure is being practical as a new treatment. Since cell products contain living cells, it is important to apply the storage method according to the characteristics of the product in order to maintain its s
Autor:
Kyongsun Pak, Shigeru Miyagawa, Hiroki Hata, Noriyuki Kashiyama, Tomomi Yamada, Akima Harada, Yoshiki Sawa, Satoshi Kainuma, Keitaro Domae, Hiroko Iseoka, Emiko Ito, Koichi Toda, Yasushi Sakata, Satsuki Fukushima, Shunsuke Saito, Maki Takeda, Yasushi Yoshikawa
Publikováno v:
Journal of the American Heart Association. 10
Background Clinical effectiveness of autologous skeletal cell‐patch implantation for nonischemic dilated cardiomyopathy has not been clearly elucidated in clinical settings. This clinical study aimed to determine the feasibility, safety, therapeuti
Autor:
Genki Horitsugi, Ryoto Sakaniwa, Hirotatsu Ohkawara, Jun Hatazawa, Shigeru Miyagawa, Yuki Mori, Yoshiki Sawa, Motoko Shiozaki, Kayako Isohashi, Shin Yajima, Satsuki Fukushima, Hiroko Iseoka, Yoshiki Sakai, Yoshichika Yoshioka, Akima Harada
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 318-331 (2019)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • Intravenously injected ONO-1301–containing nanoparticles selectively accumulated in the ischemic border area of the myocardium. • Prominent up-regulation occurred of proangiogenic cytokines such as vascular end
Highlights • Intravenously injected ONO-1301–containing nanoparticles selectively accumulated in the ischemic border area of the myocardium. • Prominent up-regulation occurred of proangiogenic cytokines such as vascular end