Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Hiroko Hama"'
Autor:
Nathan L. Alderson, Hiroko Hama
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1203-1208 (2009)
Sphingolipids are ubiquitous components of eukaryotic cells that regulate various cellular functions. In many cell types, a fraction of sphingolipids contain 2-hydroxy fatty acids, produced by fatty acid 2-hydroxylase (FA2H), as the N-acyl chain of c
Externí odkaz:
https://doaj.org/article/29ae817da63c493883a531bb9a00c642
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 153-161 (2008)
Myelin in the mammalian nervous system has a high concentration of galactolipids [galactosylceramide (GalCer) and sulfatide] with 2-hydroxy fatty acids. We recently reported that fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is the major
Externí odkaz:
https://doaj.org/article/f8b4b01bf1154ac4953caea7492e78d8
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 12, Pp 2772-2780 (2006)
2-Hydroxy fatty acids are relatively minor species of membrane lipids found almost exclusively as N-acyl chains of sphingolipids. In mammals, 2-hydroxy sphingolipids are uniquely abundant in myelin galactosylceramide and sulfatide. Despite the well-d
Externí odkaz:
https://doaj.org/article/46e0e224c84d4daca9bf0ff0cb56e463
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1569-1575 (2005)
Fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is an enzyme responsible for the de novo synthesis of sphingolipids containing 2-hydroxy fatty acids. 2-Hydroxy sphingolipids are highly abundant in the brain, as major myelin galactolipids (
Externí odkaz:
https://doaj.org/article/b313be916c344dd4b19a32b034c63be2
Autor:
Xianlin Han, Kathleen A. Potter, Jacek Bielawski, Michael J. Kern, Steven S. Scherer, Jian J. Li, Hiroko Hama, George Fullbright, Sabrina W. Yum, Jagadish Kummetha Venkata, Bärbel Rohrer, P. Akbar Ali Khan, Hua Cheng
Publikováno v:
Glia. 59:1009-1021
Fatty acid 2-hydroxylase (FA2H) is responsible for the synthesis of myelin galactolipids containing hydroxy fatty acid (hFA) as the N-acyl chain. Mutations in the FA2H gene cause leukodystrophy, spastic paraplegia, and neurodegeneration with brain ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee67d548d85b9f5c94f03d85b51f578
https://doi.org/10.1002/glia.21172
https://doi.org/10.1002/glia.21172
Autor:
Jacek Bielawski, S. Michal Jazwinski, Rashna Bhandari, Solomon H. Snyder, Nathan L. Alderson, Besim Ogretmen, James C. Jiang, Hiroko Hama, Suriyan Ponnusamy
Publikováno v:
Journal of Biological Chemistry. 283:27514-27524
In this study, we investigated the roles of very long-chain fatty acid (VLCFA) synthesis by fatty acid elongase 3 (ELO3) in the regulation of telomere length and life span in the yeast Saccharomyces cerevisiae. Loss of VLCFA synthesis via deletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66968cb849d1d9facc8a59002737e661
https://doi.org/10.1074/jbc.m802980200
https://doi.org/10.1074/jbc.m802980200
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 153-161 (2008)
Myelin in the mammalian nervous system has a high concentration of galactolipids [galactosylceramide (GalCer) and sulfatide] with 2-hydroxy fatty acids. We recently reported that fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1ffece46ac22d4ebda98617c375c35
http://www.sciencedirect.com/science/article/pii/S0022227520428901
http://www.sciencedirect.com/science/article/pii/S0022227520428901
Publikováno v:
Journal of Architecture and Planning (Transactions of AIJ). 73:1477-1484
In this paper, we first figured out the planning trend of nursing homes with small group units through gathering case examples and typifying spatial composition. Then, the influence of spatial composition on residents' living aspects in these facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70af0ac372dede26e0665abe8c341d9b
https://doi.org/10.3130/aija.73.1477
https://doi.org/10.3130/aija.73.1477
Autor:
Hiroko Hama, Kathleen A. Willet
FA2H encodes a fatty acid 2-hydroxylase essential for the proper functioning of the nervous system. FA2H introduces a 2-hydroxyl group to the N-acyl chain of a major myelin lipid, galactosylceramide. Three types of Fa2h knockout mice have been report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c675bb1dceebbee3902a577a068ff5
https://doi.org/10.1016/b978-0-12-405195-9.00060-3
https://doi.org/10.1016/b978-0-12-405195-9.00060-3
Autor:
Rami R. Ajjuri, Yousuf Ali, Giuseppe Arena, Tetsuo Ashizawa, Georg Auburger, Devika P. Bagchi, Barbara Baldo, Sally L. Baxter, Robert F. Berman, Lester I. Binder, Craig Blackstone, Carlo Breda, Jonathan M. Brotchie, Edward A. Burton, Diany Paola Calderon, Guy A. Caldwell, Kim A. Caldwell, M. Angela Cenci, Jianmin Chen, Marie-Francoise Chesselet, Lyndsey E. Collins-Praino, Carlo Colosimo, Benjamin Combs, Mercè Correa, Maria Cristina D’Adamo, Helena Dai, Debkanya Datta, Mark P. DeAndrade, Paula Dietrich, Ioannis Dragatsis, David Eidelberg, Sherif F. El-Khamisy, Craig L. Evinger, Coralie Fassier, Maciej Figiel, Susan H. Fox, Veronica Francardo, Amanda A.H. Freeman, Steven Frucht, John Gardiner, Benoit Giasson, Flaviano Giorgini, Suzana Gispert, Pilar González-Cabo, Viviana Gradinaru, Marleshia Hall, Hiroko Hama, Adrian Handforth, Susan Hayflick, Jamilé Hazan, Peter Hedera, Gary A. Heiman, Karl Herrup, Ellen J. Hess, Patrick Hickey, Diana S. Himmelstein, Pieter J. Hoekstra, Corinne Houart, Michael Ryan Hunsaker, Hanna Iderberg, Vernic Jackson-Lewis, Joseph Jankovic, H.A. Jinnah, Tarja Joensuu, Tom M. Johnston, Keith A. Josephs, Nicholas M. Kanaan, Kamran Khodakhah, Kwang-Soo Kim, F. Klinker, Gurdeep S. Kooner, Outi Kopra, Paul T. Kotzbauer, Elena Kozina, Florian Krismer, Wlodzimierz J. Krzyzosiak, Korah P. Kuruvilla, Daniela Kuzdas, Charalambos P. Kyriacou, Blair R. Leavitt, Mark S. LeDoux, Anna-Elina Lehesjoki, Deranda Lester, Jada Lewis, Jiali Li, D. Liebetanz, Hanna Lindgren, Giovanna R. Mallucci, Amandeep Mann, Russell L. Margolis, Robert P. Mason, Gelareh Mazarei, Michael P. McDonald, Judith Melki, Aurélie Méneret, Mariana Moscovich, Irene Neuner, Janis M. O’Donnell, Janneth Oleas, William G. Ondo, Puneet Opal, Harry T. Orr, Emily F. Ozdowski, Massimo Pandolfo, Peristera Paschou, Juan M. Pascual, Amar Patel, Neepa Patel, João N. Peres, Mauro Pessia, Åsa Petersén, Simona Petrucci, Ronald F. Pfeiffer, Nicolás M. Phielipp, Ilse Sanet Pienaar, Christopher Pittenger, Mark R. Plummer, Samantha Podurgiel, Serge Przedborski, Andreas Puschmann, Lawrence T. Reiter, Yan Ren, Benoît Renvoisé, Samuel J. Rose, Owen A. Ross, Emmanuel Roze, Kai Ruan, Dobrila D. Rudnicki, Naruhiko Sahara, Wataru Sako, John D. Salamone, Subhabrata Sanyal, Thomas L. Saunders, Susanne A. Schneider, Eva C. Schulte, Jared J. Schwartzer, Nina T. Sherwood, Ody Sibon, Richard J. Smeyne, Mark Stacy, Philip Starr, Brian E. Staveley, Nadia Stefanova, S.H. Subramony, Nicole Swann, Pawel M. Switonski, Wojciech J. Szlachcic, Kwok-Keung Tai, Valeria Tiranti, Daniel D. Truong, Henna Tyynismaa, Aziz M. Uluğ, Enza M. Valente, Jay A. Van Gerpen, Rafael P. Vázquez-Manrique, Satya Vemula, Marie Vidailhet, Ruth H. Walker, Sarah M. Ward, Owen S. Wells, Gregor K. Wenning, Kathleen A. Willet, Juliane Winkelmann, Zbigniew K. Wszolek, Jianfeng Xiao, X. William Yang, Emil Ylikallio, Fumiaki Yokoi, Zhenyu Yue, R. Grace Zhai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb6b796146860f53192cc50e4f17a42
https://doi.org/10.1016/b978-0-12-405195-9.01002-7
https://doi.org/10.1016/b978-0-12-405195-9.01002-7