Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hiroko HIRAOKA"'
Autor:
Chung Chew Hwang, Saori Umeki, Masahito Kubo, Toshiharu Hayashi, Hiroshi Shimoda, Masami Mochizuki, Ken Maeda, Kenji Baba, Hiroko Hiraoka, Matt Coffey, Masaru Okuda, Takuya Mizuno
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73555 (2013)
The usage of reovirus has reached phase II and III clinical trials in human cancers. However, this is the first study to report the oncolytic effects of reovirus in veterinary oncology, focusing on canine mast cell tumor (MCT), the most common cutane
Externí odkaz:
https://doaj.org/article/f31d735bb2544fa8b15245950e11dad8
Autor:
Kenji Baba, Masahito Kubo, Hiroko Hiraoka, Hiroki Sakai, Osamu Sakai, Masashi Sakurai, Takuya Mizuno, Masaru Okuda
Publikováno v:
The Journal of Veterinary Medical Science
Wilms' tumor 1 (WT1) expression has been investigated in various human cancers as a target molecule for cancer immunotherapy. However, few studies have focused on WT1 expression in dogs. Firstly, cDNA of canine WT1 (cWT1) was molecularly cloned from
Autor:
Yumiko Shimoyama, Kenji Baba, Yumi Hirata, Satoshi Kambayashi, Takuya Mizuno, Masaya Igase, Miki Iwata, Takako Shimokawa Miyama, Masaru Okuda, Hiroko Hiraoka
Publikováno v:
The Journal of Veterinary Medical Science
A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb was revealed with bimodal monoclonal gammopathy composed of IgA by immunoelectrophoresis and immunofixation. Approximately 1 month after referral, the cat die
Autor:
Takuma Yanase, Yoshiho Takeda, Takuya Mizuno, Masaya Igase, Yasuo Ema, Masaru Okuda, Saori Umeki, Hiroko Hiraoka
Publikováno v:
Veterinary and Comparative Oncology. 14:95-106
The cyclin-dependent kinase (CDK) inhibitor, flavopiridol, was tested as a potential new cancer therapeutic agent to treat canine lymphoma by examining its effect on cell growth of canine lymphoma cell lines in vitro. Flavopiridol induced profound ce
Autor:
Rieko Nakanishi, Manabu Kadoya, Shinobu Nakamura, Mieko Matsumoto, Tetsutaro Sugiura, Yuka Sugio, Megumi Kurita, Ayumi Harada, Hiroko Hiraoka
Publikováno v:
SANGYO EISEIGAKU ZASSHI. 56:121-127
OBJECTIVES Specific Health Examinations and Guidance (Tokutei kenko shinsa/Tokutei hoken shido) are provided for people over 40 years of age to reduce the incidence of metabolic syndrome (MetS). In the present study, we evaluated the importance of we
Autor:
Kazuhito Itamoto, Masaru Okuda, Kenji Baba, Hiroshi Sato, Takuya Mizuno, Akiteru Amimoto, Hiroko Hiraoka, Kozue Kitagawa
Publikováno v:
Journal of Veterinary Medical Science. 74:775-778
Two dogs, emigrated from Zambia and China to Japan, were diagnosed with Ehrlichia canis infection. Both cases had thrombocytopenia, non-regenerative anemia, and hypergloblinemia with polyclonal gammopathy. Case 1 had ataxia of the hind limbs. Severe
Autor:
Masaru Okuda, Yuko Wada, Kazuhito Itamoto, Takuya Mizuno, Kenji Baba, Takumi Okawa, Hiroko Hiraoka
Publikováno v:
Journal of Veterinary Medical Science. 74:677-680
Second malignancies are frequent complications in human patients with chronic lymphocytic leukemia (CLL). However, the clinical details and outcome of this phenomenon were unclear in their canine counterparts. Here, we report a dog with high-grade ly
Autor:
Koji Minami, Takuya Mizuno, Takako Shimokawa Miyama, Chihiro Yoshioka, Masaru Okuda, Kazuhito Itamoto, Hiroko Hiraoka, Takumi Okawa
Publikováno v:
Journal of Veterinary Medical Science. 72:363-367
We performed continuous renal replacement therapy (CRRT) in clinically healthy dogs (n=7) to evaluate the utility of nafamostat mesilate (NM) as an anticoagulant. In 3 of the 7 dogs, CRRT had to be discontinued before the target duration due to coagu
Autor:
Hiroko Hiraoka, Toshiharu Hayashi, Yuki Matsukane, Masaru Okuda, Masahiro Morimoto, Natsumi Shimoyama, Yoshiho Takeda, Chihiro Yoshioka, Takuya Mizuno
Publikováno v:
Veterinary Dermatology. 20:72-79
An 11-year-old Shih Tzu presented with crusting and erythema, mainly on the abdomen and the root of the tail. Based on histopathological findings, blood examinations and necropsy findings, the condition was diagnosed as superficial necrolytic dermati
Autor:
Masaru Okuda, Munekazu Nakaichi, Naoki Kaneko, Takako Shimokawa Miyama, Yuko Wada, Kazuhito Itamoto, Hiroko Hiraoka, Takuya Mizuno, Yoshifumi Yamamoto, Tomoko Takahashi, Toshihiro Watari
Publikováno v:
Journal of Veterinary Medical Science. 71:555-559
We evaluated the usefulness of polymerase chain reaction for antigen receptor gene rearrangement analysis (PARR) of endoscopic biopsy specimens for diagnosis of canine alimentary lymphoma. Two endoscopic biopsy specimens were obtained from each lesio