Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Hiroko Fukami"'
Autor:
Tetsuya Tsukamoto, Masami Yamamoto, Akihiro Hirata, Hiroko Fukami, Masae Tatematsu, Moriaki Kusakabe, Hiroki Sakai, Akemi Yoshikawa
Publikováno v:
Cancer Letters. 239:205-211
Considerable rodent strain differences have been documented with regard to susceptibility to colon carcinogens. To clarify mechanisms, chimeras of susceptible strain C3H and relatively resistant strain C57BL/6N (B6) mice were exposed to a colonotropi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b30749d766d7012591a44ff2330fbf0
https://doi.org/10.1016/j.canlet.2005.08.004
https://doi.org/10.1016/j.canlet.2005.08.004
Publikováno v:
Experimental and Toxicologic Pathology. 57:283-289
Aberrant crypt foci, consisting of morphologically irregular crypts, are thought to be precancerous lesions for colorectal cancers. For analysis of individual crypts, F344 rats were administered weekly subcutaneous injections of 1,2-dimethylhydrazine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d8d372be4e91920f8772cf300029c7
https://doi.org/10.1016/j.etp.2005.10.004
https://doi.org/10.1016/j.etp.2005.10.004
Cytotoxic and Mutagenic Effects of Chronic Low-Dose-Rate Irradiation onTERT-Immortalized Human Cells
Autor:
Yuko Hayashi, Kanji Ishizaki, Michinari Hamaguchi, Akira Tachibana, Shigekazu Nakatsugawa, Hideaki Nakamura, Hiroko Fukami
Publikováno v:
Radiation Research. 163:283-288
To analyze the genetic effects of low-dose-rate radiation on human cells, we used human telomere reverse transcriptase (TERT)-immortalized fibroblast cells obtained from normal individuals. We studied the effect of low-dose-rate (0.3 mGy/ min) and hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839b37658d285a1fca10a40e6462dccf
https://doi.org/10.1667/rr3310
https://doi.org/10.1667/rr3310
Autor:
Yoshihiro Yamane, Hiroko Fukami, Kanji Ishizaki, Masayuki Shinoda, Shunzo Hatooka, Hiroshi Kumimoto, Yoshio Nishimoto
Publikováno v:
International Journal of Cancer. 108:228-231
Recent studies of various cancers, such as those of the breast, head and neck, bladder and lung, reported that 46-64% of somatic mutations in the D-loop region of mitochondrial DNA (mtDNA) are observed. However, in esophageal cancer, only a low rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047954857adc26b16133fbaff6d286c9
https://doi.org/10.1002/ijc.11564
https://doi.org/10.1002/ijc.11564
Autor:
Keiji Wakabayashi, Manami Inoue, Harunari Tanaka, Tetsuya Tsukamoto, Mami Takahashi, Hiroko Fukami, Masae Tatematsu
Publikováno v:
Japanese Journal of Cancer Research : Gann
Alteration of adenomatous polyposis coli (APC) is known to be an early event in neoplasia, causing activation of the beta-catenin / Tcf pathway. Although it is thought that alterations in APC and beta- catenin may complement one another, the contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b21d97df92b636bc6c657c4e9369f2
https://doi.org/10.1111/j.1349-7006.2000.tb01015.x
https://doi.org/10.1111/j.1349-7006.2000.tb01015.x
Autor:
Masami Yamamoto, Tetsuya Tsukamoto, Manami Inoue, Yoko Nishikawa, Ken Ichi Kozaki, Hiroko Fukami, Masae Tatematsu, Keiji Wakabayashi
Publikováno v:
Japanese Journal of Cancer Research : Gann
Scopus-Elsevier
Scopus-Elsevier
Aberrant crypt foci (ACF) are generally considered to be preneoplastic lesions for colon cancer. To assess their induction by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a colon carcinogen, we performed a sequential study of ACF morpholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd999d159d7c6b235ff3fd9f1facc843
http://europepmc.org/articles/PMC5926130
http://europepmc.org/articles/PMC5926130
Autor:
Hiroko Fukami, Masae Tatematsu, Moriaki Kusakabe, Yoshiki Sugimura, Masami Yamamoto, Gerald R. Cunha, Joshua H. Lipschutz
Publikováno v:
Cells Tissues Organs. 165:57-66
Though the first mammalian chimera was reported in 1961, suitable markers for different animal strains which are easily detectable in histological sections of all or most organs have not existed. Chimeric mice were produced having an excellent histol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fd10964357850afe8c0fa8d2dd9ecd
https://doi.org/10.1159/000016675
https://doi.org/10.1159/000016675
Autor:
Takeshi Oohara, Akemi Yoshikawa, Atsushi Sugiyama, Michio Kaminishi, Tatsuo Ikeno, Hiroko Fukami, Masae Tatematsu, Nobuyuki Shimizu, Masami Yamamoto
Publikováno v:
Japanese Journal of Cancer Research : Gann
An animal model of stomach carcinogenesis was established using Mongolian gerbils with N-methyl-N-nitrosourea (MNU) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) as the carcinogens. In addition, the sensitivity of these gerbils to Helicobacter pylo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039f40e5402ee663ac53cd4454cb19d7
http://europepmc.org/articles/PMC5921771
http://europepmc.org/articles/PMC5921771
Autor:
Ken Ichi Inada, Hiroko Fukami, Masae Tatematsu, M. Ichinose, Takasuke Yamachika, Yasunobu Fujimitsu, Hayao Nakanishi
Publikováno v:
Japanese Journal of Cancer Research : Gann
Morphological analysis of isolated colonic crypts in rats, postnatally, indicated that the crypts reproduce themselves by a fission mechanism, the division beginning at the crypt base and proceeding upwards until there are two separate crypts. Occasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db4d3caf8d89123a14f65e15d954892
https://doi.org/10.1111/j.1349-7006.1996.tb03133.x
https://doi.org/10.1111/j.1349-7006.1996.tb03133.x
Autor:
Masami Yamamoto, Hiroko Fukami, Teruyo Sakakura, Masae Tatematsu, Noriaki Kusakabe, Tsuneo Masui, Hayao Nakanishi
Publikováno v:
Cancer Letters. 83:37-42
The clonal growth of gastric carcinomas was investigated immunohistochemically in C3H ↔ BALB c chimeras using a stram specific antibody. C3H, BALB c and chimeric mice were given N -methyl- N -nitrosourea 0.5 mg/mice once a week for a total of 10 ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94db48a525d5a81dba013fc70b00fcce
https://doi.org/10.1016/0304-3835(94)90296-8
https://doi.org/10.1016/0304-3835(94)90296-8