Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Hiroko, Shibata"'
Autor:
Masato Kiyoshi, Makoto Nakakido, Abdur Rafique, Minoru Tada, Michihiko Aoyama, Yosuke Terao, Satoru Nagatoishi, Hiroko Shibata, Teruhiko Ide, Kouhei Tsumoto, Yuji Ito, Akiko Ishii-Watabe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Antibody–drug conjugates are powerful tools for combatting a wide array of cancers. Drug conjugation to a therapeutic antibody often alters molecular characteristics, such as hydrophobicity and effector function, resulting in quality deter
Externí odkaz:
https://doaj.org/article/a4721243f36f459b99c6c84c9ea72704
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:621-629
Autor:
Hiroko Shibata, Kazuko Nishimura, Takuya Maeda, Masamitsu Honma, Yukihiro Goda, Akiko Ishii-Watabe, Yoshiro Saito
Publikováno v:
Bioanalysis. 14:325-340
Background: With the spread of COVID-19, anti-SARS-CoV-2 antibody tests have been utilized. Herein we evaluated the analytical performance of anti-SARS-CoV-2 antibody test kits using a new reference standard prepared from COVID-19 patient sera. Metho
Autor:
Hiroko Shibata, Hiroyuki Yoshida, Ken-ichi Izutsu, Chikako Yomota, Yukihiro Goda, Haruhiro Okuda
Publikováno v:
AAPS Open, Vol 2, Iss 1, Pp 1-11 (2016)
Abstract The rapidly growing medical expense going with aging population in Japan requires the use of generic products derived from off-patent active pharmaceutical ingredients (APIs) formulations to reduce the financial burden for the national healt
Externí odkaz:
https://doaj.org/article/b2205ae2870e4f5d995b63cc51038396
Autor:
Hiroko Shibata, Yusuke Nomura, Tsuyoshi Kawakami, Eiichi Yamamoto, Daisuke Ando, Nahoko Uchiyama, Hiroko Tokumoto, Tatsuo Koide, Hideyuki Sakoda, Hiroyuki Yoshida, Yasuhiro Abe, Takashi Hakamatsuka, Yoshiaki Ikarashi, Yuji Haishima, Akiko Ishii-Watabe, Ken-ichi Izutsu, Masamitsu Honma, Yukihiro Goda
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 142(8)
Particular batches of Moderna mRNA Coronavirus Disease 2019 (COVID-19) vaccine were recalled after foreign particles were found in some vaccine vials at the vaccination site in Japan in August 2021. We investigated the foreign particles at the reques
Publikováno v:
Journal of Pharmaceutical Sciences. 110:1189-1196
Pre-filled syringes (PFS) have been in widespread use as an administration device for therapeutic antibodies in recent decades. Generally, the inner barrel and syringe of PFS are coated with silicone oil (SO) for lubrication. Multiple studies have fo
Autor:
Hiroko Shibata, Masahiro Terabe, Yuriko Shibano, Satoshi Saitoh, Tomohiro Takasugi, Yu Hayashi, Shinji Okabe, Yuka Yamaguchi, Hidehito Yasukawa, Hiroyuki Suetomo, Kazuhiro Miyanabe, Naomi Ohbayashi, Michiko Akimaru, Shuntaro Saito, Daisuke Ito, Atsushi Nakano, Shota Kojima, Yuya Miyahara, Kenji Sasaki, Takahiro Maruno, Masanori Noda, Masato Kiyoshi, Akira Harazono, Tetsuo Torisu, Susumu Uchiyama, Akiko Ishii-Watabe
Publikováno v:
Journal of pharmaceutical sciences. 111(10)
In this study, we conducted a collaborative study on the classification between silicone oil droplets and protein particles detected using the flow imaging (FI) method toward proposing a standardized classifier/model. We compared four approaches, inc
Autor:
Hideki Sezutsu, Ken-Ichiro Tatematsu, Hiroko Shibata, Akiko Ishii-Watabe, Masato Kiyoshi, Minoru Tada
Publikováno v:
Journal of Biochemistry
Therapeutic proteins expressed using transgenic animals have been of great interest for several years. Especially, transgenic silkworm has been studied intensively because of its ease in handling, low-cost, high-yield and unique glycosylation pattern
Autor:
Maki Oiwa-Monna, Satoshi Takahashi, Masato Suzuki, Masamichi Isobe, Osamu Takahashi, Arinobu Tojo, Mai Mizusawa, Hiroko Shibata, Seiko Kato, Takaaki Konuma
Publikováno v:
International Journal of Hematology. 111:858-868
Severe bacterial infections are a serious problem after cord blood transplantation (CBT). Colonization with multidrug-resistant Gram-negative rods (MRGNR) is associated with increased morbidity and mortality after allogeneic hematopoietic cell transp
Autor:
Takaki Nakajima, Kazuya Nagano, Yuka Fukuda, Yu Ishima, Hiroko Shibata, Ryo Isaka, Tian-qi Zhang, Yuya Haga, Kazuma Higashisaka, Hirofumi Tsujino, Tatsuhiro Ishida, Akiko Ishii-Watabe, Yasuo Tsutsumi
Publikováno v:
Journal of pharmaceutical sciences. 111(5)
Bioconjugation with polyethylene glycol (PEG) is important for protein drug development as it has improved biological stability. In contrast, proteins including PEGylated ones are susceptible to physicochemical stresses. Particularly, protein drugs i