Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hiroko, Nakai"'
Autor:
Mototsugu Watanabe, Hiroko Nakai, Tatsuya Ohara, Kengo Kawasaki, Shinji Murosaki, Yoshitaka Hirose
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Heat-killed Lactiplantibacillus plantarum L-137 (HK L-137) has been suggested to enhance the intestinal barrier in obese mice, leading to improvement of metabolic abnormalities and adipose tissue inflammation, and in healthy humans with over
Externí odkaz:
https://doaj.org/article/e261d26a1bcf4eafa9b14534efe5d2ba
Autor:
Rieko Yoshitake, Hiroko Nakai, Manato Ebina, Kengo Kawasaki, Shinji Murosaki, Yoshitaka Hirose
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/c7a25083ab6d4cb7ab09882eee244cff
Autor:
Rieko Yoshitake, Hiroko Nakai, Manato Ebina, Kengo Kawasaki, Shinji Murosaki, Yoshitaka Hirose
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
To determine whether consuming heat-killed Lactiplantibacillus plantarum L-137 (HK L-137) influences skin functions, we performed a randomized, placebo-controlled, double-blind study in healthy participants who were conscious of dry skin. A total of
Externí odkaz:
https://doaj.org/article/f81c22b7397a4622942a78c008268ce7
Autor:
Hiroko Nakai, Shinji Murosaki, Yoshihiro Yamamoto, Michiko Furutani, Rumiko Matsuoka, Yoshitaka Hirose
Publikováno v:
Journal of Immunotoxicology, Vol 18, Iss 1, Pp 127-135 (2021)
Heat-killed Lactobacillus plantarum L-137 (HK L-137) promotes immune function in animals. In healthy people, T-cell proliferation was shown to be enhanced by taking 10 mg HK L-137 daily for 12 weeks. However, the safety and efficacy of higher doses o
Externí odkaz:
https://doaj.org/article/8c8d038d6f364b658e71a7e2defbba4a
Autor:
Yumiko, Shirai, Shunsuke, Morita, Takashi, Iwata, Hiroko, Nakai, Mayu, Yoshikawa, Kazuma, Yoshida, Hiroshi, Iwamoto, Kazuhiro, Miyaji, Yoshinaga, Okugawa, Chikao, Miki, Koji, Tanaka
Publikováno v:
Oncology Letters. 24
The present study investigated the effects of dietary supplementation combined with fish oil containing relatively low levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the inflammatory and nutritional status of patients with ep
Autor:
Hiroko, Nakai, Yoshiki, Tsuchiya, Nobuya, Koike, Taiki, Asano, Morio, Ueno, Yasuhiro, Umemura, Yuh, Sasawaki, Ryutaro, Ono, Junji, Hamuro, Chie, Sotozono, Kazuhiro, Yagita
Publikováno v:
Investigative Opthalmology & Visual Science. 63:16
To investigate circadian clock oscillation and circadian global gene expression in cultured human corneal endothelial cells (cHCECs) to elucidate and assess the potential function of circadian regulation in HCECs.In this study, we introduced a circad
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The purpose of this study was to investigate the microbiome in the meibum, conjunctival sac, and eyelid skin in young and elderly healthy subjects, and analyze the effect that age, sex, and region have on microbiome composition. Methods This
Publikováno v:
Nihon Chikusan Gakkaiho. 88:321-328
Publikováno v:
Microbiology and immunology. 63(9)
Heat-killed Lactobacillus plantarum L-137 (HK L-137), an immunobiotic lactic acid bacterium, has been reported to enhance IFN-γ production through induction of IL-12. In this study, we investigated the effects of HK L-137 on skin moisturizing and pr
Autor:
Yasuhito Shirai, Nobuyuki Takei, Akio Nakashima, Shuji Ueda, Ushio Kikkawa, Kenta Maruo, Naoaki Saito, Ryosuke Tsumagari, Hiroko Nakai, Minoru Yamanoue
Publikováno v:
Neurochemistry International. 134:104645
Diacylglycerol kinase β (DGKβ) is an enzyme converting DG to phosphatidic acid (PA) and is specifically expressed in neurons, especially those in the cerebral cortex, hippocampus and striatum. We previously reported that DGKβ induces neurite outgr