Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Hiroki Yoneyama"'
Autor:
Seiji Komeda, Hiroki Yoneyama, Masako Uemura, Takahiro Tsuchiya, Miyuu Hoshiyama, Tomoya Sakazaki, Keiichi Hiramoto, Shinya Harusawa
Publikováno v:
Data in Brief, Vol 40, Iss , Pp 107697- (2022)
In this data file, the synthetic procedures for the preparation of a series of anticancer tetrazolato-bridged dinuclear platinum(II) complexes ([{cis-Pt(NH3)2}2(μ-OH)(μ-5-R-tetrazolato-N2,N3)]n+ (n = 1 or 2, tetrazolato-bridged complexes)) and of t
Externí odkaz:
https://doaj.org/article/1d93490e8fc04ad9b86563d3cb229b15
Autor:
Yoshihide Usami, Yoshino Mizobuchi, Mai Ijuin, Takeshi Yamada, Mizuki Morita, Koji Mizuki, Hiroki Yoneyama, Shinya Harusawa
Publikováno v:
Marine Drugs, Vol 20, Iss 7, p 438 (2022)
The enantiomers of 6-fluoro-, 6-bromo-, and 6-iodopericosine A were synthesized. An efficient synthesis of both enantiomers of pericoxide via 6-bromopericosine A was also developed. These 6-halo-substituted pericosine A derivatives were evaluated in
Externí odkaz:
https://doaj.org/article/0208dabc39e447c5b9989fb08527901d
Autor:
Yoshihide Usami, Yumika Kubo, Toshiki Takagaki, Nao Kuroiwa, Jun Ono, Kohei Nishikawa, Ayaka Nakamizu, Yuya Tatsui, Shinya Harusawa, Noboru Hayama, Hiroki Yoneyama
Publikováno v:
Molecules, Vol 26, Iss 11, p 3370 (2021)
The direct 4-alkoxylation of 4-iodo-1H-pyrazoles with alcohols was achieved by a CuI-catalyzed coupling protocol. The optimal reaction conditions employed excess alcohol and potassium t-butoxide (2 equiv) in the presence of CuI (20 mol%) and 3,4,7,8-
Externí odkaz:
https://doaj.org/article/0fe5ba9fd7484365b0381338a41df0c9
Publikováno v:
Molecules, Vol 25, Iss 20, p 4634 (2020)
Alkylamino coupling reactions at the C4 positions of 4-halo-1H-1-tritylpyrazoles were investigated using palladium or copper catalysts. The Pd(dba)2 catalyzed C-N coupling reaction of aryl- or alkylamines, lacking a β-hydrogen atom, proceeded smooth
Externí odkaz:
https://doaj.org/article/d6d224e7db424004a02696e1f6455800
Autor:
Yoshihide Usami, Megumi Higuchi, Koji Mizuki, Mizuki Yamamoto, Mao Kanki, Chika Nakasone, Yuya Sugimoto, Makio Shibano, Yoshihiro Uesawa, Junko Nagai, Hiroki Yoneyama, Shinya Harusawa
Publikováno v:
Marine Drugs, Vol 18, Iss 4, p 221 (2020)
Inspired by the significant α-glucosidase inhibitory activities of (+)- and (−)-pericosine E, we herein designed and synthesized 16 analogs of these marine natural products bearing a methoxy group instead of a chlorine atom at C6. Four of these co
Externí odkaz:
https://doaj.org/article/79470c8115fe4f6a838e08e202da2296
Publikováno v:
Inorganics, Vol 7, Iss 1, p 5 (2019)
Tetrazolato-bridged dinuclear platinum(II) complexes ([{cis-Pt(NH3)2}2(μ-OH)(μ-5-R-tetrazolato-N2,N3)]2+; tetrazolato-bridged complexes) are a promising source of next-generation platinum-based drugs. β-Cyclodextrin (β-CD) forms inclusion complex
Externí odkaz:
https://doaj.org/article/0b54b0b2e1384de9a86b8ad846546a73
Autor:
Yoshihide Usami, Kodai Sumimoto, Azusa Kishima, Yuya Tatsui, Hiroki Yoneyama, Shinya Harusawa
Publikováno v:
Molecules, Vol 24, Iss 2, p 296 (2019)
Three types of pyrazole-fused heterobicycles, i.e., 1,5-, 1,7-, and 2,5-dihydropyrano[3,2-c]pyrazoles, were synthesized from 4-allyloxy-1H-pyrazoles. A sequence of the Claisen rearrangement of 4-allyloxy-1H-pyrazoles, ruthenium-hydride-catalyzed doub
Externí odkaz:
https://doaj.org/article/d8040f34b8ed47eb9abb93d6017cbc34
Publikováno v:
Molecules, Vol 23, Iss 3, p 592 (2018)
Synthesis of novel pyrazole-fused heterocycles, i.e., dihydro-1H- or 2H-oxepino[3,2-c]pyrazoles (6 or 7) from 4-allyloxy-1H-pyrazoles (1) via combination of Claisen rearrangement and ring-closing metathesis (RCM) has been achieved. A suitable catalys
Externí odkaz:
https://doaj.org/article/7452551b25b64e359b639a2a9df51ac0
Autor:
Yoshihide Usami, Koji Mizuki, Rikiya Kawahata, Makio Shibano, Atsuko Sekine, Hiroki Yoneyama, Shinya Harusawa
Publikováno v:
Marine Drugs, Vol 15, Iss 1, p 22 (2017)
Pericosine E (6), a metabolite of Periconia byssoides OUPS-N133 was originally isolated from the sea hare Aplysia kurodai, which exists as an enantiomeric mixture in nature. The enantiospecific syntheses of both enantiomers of Periconia byssoides OUP
Externí odkaz:
https://doaj.org/article/b720dfd1690247c49509bd61d575f2c1
Autor:
Yoshihide Usami, Hiroki Yoneyama, Mano Adachi, Aoshi Morita, Maki Nakagawa, Miho Baba, Kanako Yamawaki, Noboru Hayama, Shinya Harusawa
Publikováno v:
Synthesis. 55:945-958
Microwave irradiation of 2-alkynyl-5-(phenyl or alkyl)tetrazoles affords 2-(phenyl or alkyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles via intramolecular [3+2] cyclization of nitrile-imine intermediates. In the present method, the use of 5-alkyltetrazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070d9337ce232004334e15b05f3c0d86
https://doi.org/10.1055/a-1961-8504
https://doi.org/10.1055/a-1961-8504