Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Hiroki Takahata"'
Autor:
Shoichiro Mizukami, Koji Imai, Hiroki Takahata, Hiroyuki Takahashi, Shingo Shimada, Yuki Kamikokura, Hidemasa Kawabata, Mishie Tanino, Yusuke Mizukami, Hideki Yokoo
Publikováno v:
Case Reports in Gastroenterology, Vol 18, Iss 1, Pp 422-430 (2024)
Introduction: Focal autoimmune pancreatitis (AIP) without elevated serum IgG4 levels presents a diagnostic challenge compared to pancreatic tumors, often leading to surgical intervention. Case Presentation: We report a case of serum IgG4-negative foc
Externí odkaz:
https://doaj.org/article/1b0dd326a5214b2ea6357b4027fede15
Autor:
Ryo Kitamura, Tsugunobu Andoh, Shizuka Mizoguchi, Yukako Saito, Hiroki Takahata, Yasushi Kuraishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 4, Pp 502-510 (2014)
Bortezomib, an inhibitor of proteasome holoenzyme, is used to treat relapsed and refractory multiple myeloma. Peripheral neuropathy is a treatment-limiting adverse effect of bortezomib and is very difficult to control. In this study, we examined the
Externí odkaz:
https://doaj.org/article/dc8f33b7c5584415810e97834da51352
Publikováno v:
Molecules, Vol 18, Iss 1, Pp 1162-1173 (2013)
Synthesis of beneficial protected meso-DAP 9 by cross metathesis of the Garner aldehyde-derived vinyl glycine 1b with protected allyl glycine 2 in the presence of Grubbs second-generation catalyst was performed. Preparation of lipophilic N-acyl iE-DA
Externí odkaz:
https://doaj.org/article/edbffe903a7e4bd18819c14c29874c55
Autor:
Hiroki Takahata, Yuichi Yoshimura
Publikováno v:
Molecules, Vol 17, Iss 10, Pp 11630-11654 (2012)
Cyclonucleosides which are fixed in a specific conformation around the glycosyl bond by a carbon and heteroatom chain constitute a unique category of nucleoside derivatives. Because they are structural analogs, cyclonucleosides and oligodeoxynucleoti
Externí odkaz:
https://doaj.org/article/9c4f1b48c6e04bc2a6c4bcb0080b17db
Autor:
Yu Omori, Kenta Kagaya, Ryugo Enomoto, Atsushi Sasaki, Tsugunobu Andoh, Hiroshi Nojima, Hiroki Takahata, Yasushi Kuraishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 4, Pp 532-539 (2009)
This study was conducted to make a new mouse model of neuropathic pain due to injury to a branch of the sciatic nerve. One of three branches (sural, tibial, and common peroneal nerves) of the sciatic nerve was tightly ligated, and mechanical and cool
Externí odkaz:
https://doaj.org/article/3775314829c24fa0b43d28be9b9f5b4f
Autor:
Tsugunobu Andoh, Yuichi Yageta, Mitsuhiro Konno, Tomomi Yamaguchi-Miyamoto, Hiroki Takahata, Hiroshi Nojima, Hideo Nemoto, Yasushi Kuraishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 4, Pp 667-670 (2008)
The common adverse effect of centrally-injected μ-opioid receptor (μ-OR) agonists is pruritus. This study was conducted using mice to examine whether different subtypes of μ-OR would be responsible for pruritus and analgesia. Intracisternal inject
Externí odkaz:
https://doaj.org/article/b372ce98b7814e6abb0aebdfc093be99
Autor:
Atsushi Sasaki, Kenichi Serizawa, Tsugunobu Andoh, Kimiyasu Shiraki, Hiroki Takahata, Yasushi Kuraishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 266-273 (2008)
In the present study, we investigated whether dynamic and static allodynia would be developed in the affected dermatome in murine models of herpetic pain and postherpetic neuralgia and pharmacologically characterized the allodynia. Inoculation with h
Externí odkaz:
https://doaj.org/article/ae3a50d324ff416a9de79b034f31724a
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 37 (2007)
The asymmetric synthesis of both enantiomers of piclavines A1, A2, A3, and A4 has been achieved using an iterative asymmetric dihydroxylation with enantiomeric enhancement.
Externí odkaz:
https://doaj.org/article/89b435c9136d47d3a0491f14a9a80138
Autor:
Hiroki Takahata, Isao Adachi, Atsushi Kato, Yoshihiro Natori, Toshihiro Sakuma, Hideaki Wakamatsu, Yuichi Yoshimura, Haruka Watanabe
Publikováno v:
Tetrahedron. 75:2866-2876
We achieved synthesis of seven stereoisomers of 1-C-n-butyl-L-iminofuranose derivatives using catalytic asymmetric alkylation and Negishi coupling as key reactions. The synthetic strategy based on these key reactions was quite useful, since both α-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096bc04fbee3937d2cd328b2981d21b7
https://doi.org/10.1016/j.tet.2019.04.003
https://doi.org/10.1016/j.tet.2019.04.003
Autor:
Hiroki Takahata, Hiroshi Nojima, Tsugunobu Andoh, Eiji Ohtsuka, Hidekazu Ouchi, Tasuku Akiyama, Yasushi Kuraishi
Publikováno v:
European Journal of Pharmacology. 833:44-49
The antipruritic activity of gabapentin, an anticonvulsant, was studied in a mouse model of allergic itch. In mice sensitized by an extract of the salivary glands of the mosquito (ESGM), an intradermal injection of ESGM elicited scratching and increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c964efa4d74898eac23e104ea0faac0
https://doi.org/10.1016/j.ejphar.2018.05.037
https://doi.org/10.1016/j.ejphar.2018.05.037