Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hiroki SHIMAOKA"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 317:R240-R247
Cold-shock proteins are thought to participate in the cold-tolerant nature of hibernating animals. We previously demonstrated that an alternative splicing may allow rapid induction of functional cold-inducible RNA-binding protein (CIRBP) in the hamst
Autor:
Kazuhiro Horii, Takahiko Shiina, Shouichiro Saito, Yuuki Horii, Yuji Suzuki, Hiroki Shimaoka, Yasutake Shimizu, Sawa Onouchi
Publikováno v:
The Journal of Veterinary Medical Science
The aim of the present study was to clarify roles of ATP-dependent potassium channels (KATP channels) in motility of the striated muscle portion in the esophagus. An isolated segment of the rat esophagus was placed in an organ bath and mechanical res
Autor:
Hiroyuki Nakamori, Yuuki Horii, Kurumi Kato, Kazuhiro Horii, Takahiko Shiina, Hiroki Shimaoka, Yasutake Shimizu, Kiyotada Naitou
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 315:G631-G637
The central regulating mechanisms of defecation, especially roles of the spinal defecation center, are still unclear. We have shown that monoamines including norepinephrine, dopamine, and serotonin injected into the spinal defecation center cause pro
Autor:
Yuuki Horii, Kiyotada Naitou, Yuka Ehara, Kazuhiro Horii, Hiroki Shimaoka, Yasutake Shimizu, Shouichiro Saito, Hiroyuki Nakamori, Takahiko Shiina
Publikováno v:
The Journal of physiologyReferences. 599(5)
Key points This study showed a remarkable sex difference in responses of colorectal motility to noxious stimuli in the colorectum in rats: colorectal motility was enhanced in response to intracolonic administration of a noxious stimulant, capsaicin,
Autor:
Kazuhiro Horii, Hiroki Shimaoka, Takahiko Shiina, Yasutake Shimizu, Yuuki Horii, Hayato Suzuki
Publikováno v:
The journal of physiological sciences : JPS. 71(1)
The aim of the present study was to establish a novel method for inducing deep hypothermia in rats. Cooling rats anesthetized with isoflurane caused a time-dependent decrease in rectal temperature, but cardiac arrest occurred before their body temper
Autor:
Hidemasa Furue, Kazuhiro Horii, Kiyotada Naitou, Akihiro Yamada, Yuuki Horii, Hiroyuki Nakamori, Takahiko Shiina, Hiroki Shimaoka, Yasutake Shimizu, Hiroki Sakai
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 314:G341-G348
Colorectal motility is regulated by two defecation centers located in the brain and spinal cord. In previous studies, we have shown that administration of serotonin (5-HT) in the lumbosacral spinal cord causes enhancement of colorectal motility. Beca
Autor:
Takayuki Kawaguchi, Hiroki Shimaoka, Yasutake Shimizu, Yuuki Sano, Kahori Morikawa, Takahiko Shiina, Hiroyuki Nakamori, Kiyotada Naitou
Publikováno v:
The Journal of Physiological Sciences. 68:425-430
Central adenosine A1-receptor (A1AR)-mediated signals play a role in the induction of hibernation. We determined whether activation of the central A1AR enables rats to maintain normal sinus rhythm even after their body temperature has decreased to le
Autor:
Takahiko Shiina, Yuuki Sano, Hiroki Shimaoka, Yasutake Shimizu, Kiyotada Naitou, Hiroyuki Nakamori
Publikováno v:
The Journal of Physiological Sciences. 68:243-251
Somatostatin and its receptors are expressed in the spinal cord, but the functional roles of the peptide remain unknown. In this study, we examined the colokinetic effect of somatostatin in the spinal defecation center in anesthetized rats. Intrathec
Autor:
Yuuki Horii, Kazuhiro Horii, Akihiro Yamada, Hiroki Shimaoka, Yasutake Shimizu, Hidemasa Furue, Hiroyuki Nakamori, Takahiko Shiina, Hiroki Sakai, Kiyotada Naitou
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 317(4)
We previously demonstrated that administration of norepinephrine, dopamine, and serotonin into the lumbosacral defecation center caused propulsive contractions of the colorectum. It is known that the monoamines in the spinal cord are released mainly
Autor:
Hiroki Shimaoka, Yuuki Horii, Yasutake Shimizu, Saki Uehara, Kanako Nomura, Takahiko Shiina, Kazuhiro Horii
Publikováno v:
Biomedical research (Tokyo, Japan). 40(4)
Cold-inducible RNA-binding protein (CIRBP) plays important roles in protection against harmful effects of cold temperature. We previously found that several splicing variants of CIRBP mRNA are constitutively expressed in the heart of non-hibernating