Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Hiroki Otani"'
Autor:
Toru Kanahashi, Jun Matsubayashi, Hirohiko Imai, Shigehito Yamada, Hiroki Otani, Tetsuya Takakuwa
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Human adolescent and adult skeletons exhibit sexual dimorphism in the pelvis. However, the degree of sexual dimorphism of the human pelvis during prenatal development remains unclear. Here, we performed high-resolution magnetic resonance ima
Externí odkaz:
https://doaj.org/article/93e0a828b6b24872b432cfd7080ec090
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101245- (2022)
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and CKD is a serious global health problem. Low glomerular number is one of the risk factors for CKD; therefore, the glomerular number is associated with the risk of CKD. Increas
Externí odkaz:
https://doaj.org/article/1489c09358a446119da4ac1d91c1992a
Autor:
Akari Shintani, Hiromi Sakata-Haga, Keiichi Moriguchi, Mitsuhiro Tomosugi, Daisuke Sakai, Tsuyoshi Tsukada, Makoto Taniguchi, Masahide Asano, Hiroki Shimada, Hiroki Otani, Hiroki Shoji, Junko Hatta, Takashi Mochizuki, Toshihisa Hatta
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100024- (2021)
MC5R is known for its role in the exocrine function of sebaceous glands, but other functions in the epidermis remain unclear. This study focused on the relationship between MC5R and homeostasis in the epidermis and examined the role of MC5R in mice w
Externí odkaz:
https://doaj.org/article/6eb6a7757a1b42aab3e7d6e124fbae89
Autor:
Toshihiro Tamagawa, Torbjörn Lundh, Kenji Shigetoshi, Norihisa Nitta, Noritoshi Ushio, Toshiro Inubushi, Akihiko Shiino, Anders Karlsson, Takayuki Inoue, Yutaka Mera, Kodai Hino, Masaru Komori, Shigehiro Morikawa, Shuji Sawajiri, Shigeyuki Naka, Satoru Honma, Tomoko Kimura, Yasuhiro Uchimura, Shinji Imai, Naoko Egi, Hiroki Otani, Jun Udagawa
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232397 (2020)
Biometric ratios of the relative length of the rays in the hand have been analyzed between primate species in the light of their hand function or phylogeny. However, how relative lengths among phalanges are mechanically linked to the grasping functio
Externí odkaz:
https://doaj.org/article/aab460165d874d72897417569534fef4
Autor:
Michiru Nishita, Seung-Yeol Park, Tadashi Nishio, Koki Kamizaki, ZhiChao Wang, Kota Tamada, Toru Takumi, Ryuju Hashimoto, Hiroki Otani, Gregory J. Pazour, Victor W. Hsu, Yasuhiro Minami
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for tumor invasion. Here, we identify intraflagellar transport 20 (IFT20) as a new target of this signaling in tumors that lack primary cilia, and find that I
Externí odkaz:
https://doaj.org/article/807b6c00d37f4d82bde110d6936e5ef0
Autor:
Toru Yoshihara, Hiroyuki Satake, Toshikazu Nishie, Nozomu Okino, Toshihisa Hatta, Hiroki Otani, Chie Naruse, Hiroshi Suzuki, Kazushi Sugihara, Eikichi Kamimura, Noriyo Tokuda, Keiko Furukawa, Koichi Fururkawa, Makoto Ito, Masahide Asano
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007545 (2018)
It is uncertain which β4-galactosyltransferase (β4GalT; gene name, B4galt), β4GalT-5 and/or β4GalT-6, is responsible for the production of lactosylceramide (LacCer) synthase, which functions in the initial step of ganglioside biosynthesis. Here,
Externí odkaz:
https://doaj.org/article/14f22f1ec239459ebbbf8b434f7fbb61
Autor:
Eriko Simamura, Tomohiro Arikawa, Takayuki Ikeda, Hiroki Shimada, Hiroki Shoji, Hiroko Masuta, Yuriko Nakajima, Hiroki Otani, Hideto Yonekura, Toshihisa Hatta
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123232 (2015)
In this study, we showed that adrenocorticotropic hormone (ACTH) promoted erythroblast differentiation and increased the enucleation ratio of erythroblasts. Because ACTH was contained in hematopoietic medium as contamination, the ratio decreased by t
Externí odkaz:
https://doaj.org/article/5a275fe8e5d34800a4e428d9ef0494ec
Autor:
Hiroki Otani, Hiromasa Yamamoto, Munenori Takaoka, Masakiyo Sakaguchi, Junichi Soh, Masaru Jida, Tsuyoshi Ueno, Takafumi Kubo, Hiroaki Asano, Kazunori Tsukuda, Katsuyuki Kiura, Shinji Hatakeyama, Eiji Kawahara, Yoshio Naomoto, Shinichiro Miyoshi, Shinichi Toyooka
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129838 (2015)
TAE226, a bis-anilino pyrimidine compound, has been developed as an inhibitor of focal adhesion kinase (FAK) and insulin-like growth factor-I receptor (IGF-IR). In this study, we investigated the effect of TAE226 on non-small-cell lung cancer (NSCLC)
Externí odkaz:
https://doaj.org/article/6a7d1b9e26b24b4c9a39fa961371116e
Autor:
Hiroki Kurahashi, Mariko Taniguchi, Chikara Meno, Yoshihiro Taniguchi, Satoshi Takeda, Masato Horie, Hiroki Otani, Tatsushi Toda
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 208-217 (2005)
Fukuyama-type congenital muscular dystrophy (FCMD), associated with brain malformation due to defects in neuronal migration, is caused by mutations in fukutin. Several lines of evidence suggest that the fukutin protein plays a pivotal role in synthes
Externí odkaz:
https://doaj.org/article/16a5c868c46e449bb8b670eda4b48eee
Autor:
Chieko Matsunari, Toru Kanahashi, Hiroki Otani, Hirohiko Imai, Shigehito Yamada, Tomohisa Okada, Tetsuya Takakuwa
Publikováno v:
The Anatomical Record. 306:515-526
The morphologies of the fetal tentorium cerebelli (TC) and brain influence each other during development. This study aimed to analyze and more comprehensively understand the three-dimensional morphogenesis of the TC and fetal brain. We examined magne