Výsledky vyhledávání - "Hiroki Honda"

Akademický článek

Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice

Autor: Yasufumi Katanasaka, Harumi Yabe, Noriyuki Murata, Minori Sobukawa, Yuga Sugiyama, Hikaru Sato, Hiroki Honda, Yoichi Sunagawa, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Toshihide Hamabe-Horiike, Philip Hawke, Maki Komiyama, Kiyoshi Mori, Koji Hasegawa, Tatsuya Morimoto

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract Protein arginine methyltransferase 5 (PRMT5) is a well-known epigenetic regulatory enzyme. However, the role of PRMT5-mediated arginine methylation in gene transcription related to cardiac fibrosis is unknown. Here we show that fibroblast-sp

Externí odkaz: https://doaj.org/article/c2bc5c10072540838079235756f4f6b3

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Akademický článek

CNFET-OCL: Open-Source Cell Libraries for Advanced CNFET Technologies

Autor: Chenlin Shi, Shinobu Miwa, Tongxin Yang, Ryota Shioya, Hayato Yamaki, Hiroki Honda

Publikováno v: IEEE Access, Vol 12, Pp 165335-165347 (2024)

In this paper, we propose CNFET-OCL, the first open-source cell libraries for 5-nm and 7-nm carbon nanotube field-effect transistor (CNFET) technologies. Our CNFET-OCL is designed to emulate the predictive 5-nm and 7-nm CNFET technologies presented i

Externí odkaz: https://doaj.org/article/5751e72816fb491db9be7d0315133e75

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Akademický článek

Maximum Likelihood Direct Zone Estimation with Antenna Beam Pattern Aware Received Signal Power

Autor: Gurusanthosh Pabbisetty, Hiroki Honda, Kazunori Hayashi, Hiroki Mori

Publikováno v: APSIPA Transactions on Signal and Information Processing, Vol 12, Iss 1 (2023)

Externí odkaz: https://doaj.org/article/f8aa7fa3f8884c7a9a93dbd03544906e

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Akademický článek

Acute bout of exercise downregulates thioredoxin‐interacting protein expression in rat contracting skeletal muscles

Autor: Song‐Gyu Ra, Emi Kawamoto, Keiichi Koshinaka, Maiko Iwabe, Yuki Tomiga, Hiroki Iizawa, Hiroki Honda, Yasuki Higaki, Kentaro Kawanaka

Publikováno v: Physiological Reports, Vol 8, Iss 11, Pp n/a-n/a (2020)

Abstract We previously reported that in rat skeletal muscle, disuse (i.e., decreased muscle contractile activity) rapidly increases thioredoxin‐interacting protein (TXNIP), which is implicated in the reduced glucose uptake. Accordingly, we sought h

Externí odkaz: https://doaj.org/article/81c0e7a1544a4e418efbf294106d8a58

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Akademický článek

The Selective Serotonin 2A Receptor Antagonist Sarpogrelate Prevents Cardiac Hypertrophy and Systolic Dysfunction via Inhibition of the ERK1/2–GATA4 Signaling Pathway

Autor: Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki Honda, Yasufumi Katanasaka, Noriyuki Murai, Yuto Kawase, Yuta Hirako, Takahiro Katagiri, Harumi Yabe, Satoshi Shimizu, Nurmila Sari, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto

Publikováno v: Pharmaceuticals, Vol 14, Iss 12, p 1268 (2021)

Drug repositioning has recently emerged as a strategy for developing new treatments at low cost. In this study, we used a library of approved drugs to screen for compounds that suppress cardiomyocyte hypertrophy. We identified the antiplatelet drug s

Externí odkaz: https://doaj.org/article/7aeb417de74a4b29a84df531f85bb03d

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Akademický článek

Utility of Over-the-Scope Clipping for Closure of a Persistent Post-Percutaneous Endoscopic Gastrostomy Fistula under Long-Term Steroid Therapy

Autor: Yoshihisa Arao, Yuichi Sato, Satoru Hashimoto, Hiroki Honda, Kazumi Yoko, Masaaki Takamura, Ken-ichi Mizuno, Masaaki Kobayashi

Publikováno v: Clinical Endoscopy, Vol 48, Iss 6, Pp 563-565 (2015)

A 50-year-old woman had a percutaneous endoscopic gastrostomy (PEG) tube placed after surgery for pharyngeal cancer. After 21 months, the PEG tube was removed due to improvement of per-oral ingestion. She had taken prednisolone for 31 years for syste

Externí odkaz: https://doaj.org/article/abe413bb74b64b8697b4f88f33d0653b

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