Zobrazeno 1 - 10
of 392
pro vyhledávání: '"Hiroki HAMADA"'
Autor:
Takahiro Nakayama, Akash K. Singh, Toshiyuki Fukutomi, Noriyuki Uchida, Yasuo Terao, Hiroki Hamada, Takahiro Muraoka, Eswaramoorthy Muthusamy, Tapas K. Kundu, Kimio Akagawa
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114101- (2024)
Summary: Syntaxin-1A (stx1a) repression causes a neurodevelopmental disorder phenotype, low latent inhibition (LI) behavior, by disrupting 5-hydroxytryptaminergic (5-HTergic) systems. Herein, we discovered that lysine acetyltransferase (KAT) 3B incre
Externí odkaz:
https://doaj.org/article/7082df1e29b6458ba0cf338791935a20
Autor:
Hiroki Hamada, Toshiaki Uemoto, Yoshitaka Tanaka, Yuki Honda, Keiichi Kitajima, Tetsuya Umeda, Atsushi Kawakami, Minori Shinya, Koichi Kawakami, Koji Tamura, Gembu Abe
Publikováno v:
Zoological Letters, Vol 5, Iss 1, Pp 1-12 (2019)
Abstract Background Teleost paired fins are composed of two endoskeletal domains, proximal and distal radials, and an exoskeletal domain, the fin ray. The zebrafish pectoral fin displays elaborately patterned radials along the anteroposterior (AP) ax
Externí odkaz:
https://doaj.org/article/f7affc3195384472855d0cc694bc45f2
Autor:
Ikuo Nakanishi, Yoshimi Shoji, Kei Ohkubo, Megumi Ueno, Kei Shimoda, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, Hiroki Hamada
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 340 (2022)
Pterostilbene (PTS), a methylated analog of resveratrol (RSV), has recently attracted much attention due to its enhanced bioavailability compared to RSV. However, little is known about the radical-scavenging mechanism of PTS. In this study, we invest
Externí odkaz:
https://doaj.org/article/5739f46030c74169b3ae230cad6448a6
Publikováno v:
Nanomaterials, Vol 11, Iss 2, p 335 (2021)
A transdermal drug delivery system (TDDS) is a method that provides drug adsorption via the skin. TDDS could replace conventional oral administration and blood administration because it is easily accessible. However, it is still difficult to design e
Externí odkaz:
https://doaj.org/article/4891d957c5db4682859ce571c4f47e8e
Publikováno v:
Molecules, Vol 25, Iss 6, p 1437 (2020)
Oxyresveratrol and gnetol are naturally occurring stilbene compounds, which have diverse pharmacological activities. The water-insolubility of these compounds limits their further pharmacological exploitation. The glycosylation of bioactive compounds
Externí odkaz:
https://doaj.org/article/172a5dc0d00445419e81917162ec444c
Autor:
Yuya Fujitaka, Hiroki Hamada, Daisuke Uesugi, Atsuhito Kuboki, Kei Shimoda, Takafumi Iwaki, Yuya Kiriake, Tomohiro Saikawa
Publikováno v:
Molecules, Vol 24, Iss 16, p 2975 (2019)
Daidzein is a common isoflavone, having multiple biological effects such as anti-inflammation, anti-allergy, and anti-aging. α-Tocopherol is the tocopherol isoform with the highest vitamin E activity including anti-allergic activity and anti-cancer
Externí odkaz:
https://doaj.org/article/ab2d621b0ae24bc3a2266afd373b3abb
Autor:
Apriliana Cahya Khayrani, Hafizah Mahmud, Aung Ko Ko Oo, Maram H. Zahra, Miharu Oze, Juan Du, Md Jahangir Alam, Said M. Afify, Hagar A. Abu Quora, Tsukasa Shigehiro, Anna Sanchez Calle, Nobuhiro Okada, Akimasa Seno, Koki Fujita, Hiroki Hamada, Yuhki Seno, Tadakatsu Mandai, Masaharu Seno
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1042 (2019)
Paclitaxel (PTX) is one of the front-line drugs approved for the treatment of ovarian cancer. However, the application of PTX is limited due to the significant hydrophobicity and poor pharmacokinetics. We previously reported target-directed liposomes
Externí odkaz:
https://doaj.org/article/bde19086775148339cc9e86fd42c0aa0
Publikováno v:
Molecules, Vol 17, Iss 5, Pp 5013-5020 (2012)
Glycosylation of vanilloids such as vanillin and 8-nordihydrocapsaicin by cultured plant cells of Eucalyptus perriniana was studied. Vanillin was converted into vanillin 4-O-b-D-glucopyranoside, vanillyl alcohol, and 4-O-b-D-glucopyranosylvanillyl al
Externí odkaz:
https://doaj.org/article/3b6df901dc1145ddbd96074d87ab7ae8
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 9, Pp 5616-5625 (2011)
The biocatalytic synthesis of xylooligosaccharides of daidzein was investigated using cultured cells of Catharanthus roseus and Aspergillus sp. β-xylosidase. The cultured cells of C. roseus converted daidzein into its 4'-O-β-glucoside, 7-O-β-gluco
Externí odkaz:
https://doaj.org/article/e18a5af7ab9942149467e84bb18281cb
Publikováno v:
Molecules, Vol 16, Iss 6, Pp 4740-4747 (2011)
The synthesis of gentiooligosaccharides of genistein and glycitein using cultured cells of Eucalyptus perriniana as biocatalysts was investigated. The cells of E. perriniana glycosylated genistein and glycitein to give the corresponding 4'-O-b-glucos
Externí odkaz:
https://doaj.org/article/1df7c0a9613c46c0a24938c80abf0a28