Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Hiroki Fujiwara"'
Autor:
Ayako Nogami, Hideki Jose Amemiya, Hiroki Fujiwara, Yoshihiro Umezawa, Shuji Tohda, Toshikage Nagao
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10372 (2024)
FMS-like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML) are associated with poor prognosis and therapy resistance. This study aimed to demonstrate that inhibiting the deubiquitinating enzymes ubiq
Externí odkaz:
https://doaj.org/article/35b1f64a038647e591d18d29b054415f
Publikováno v:
Lubricants, Vol 12, Iss 1, p 13 (2024)
Grease-lubricated rolling bearings transition from the churning phase to the channeling phase. This transition property affects grease life and torque properties. Therefore, the relationship between grease yield stress and grease degradation during o
Externí odkaz:
https://doaj.org/article/c17a143f23ef46eba4e88d97dc25817b
Publikováno v:
IEEE Access, Vol 9, Pp 62642-62652 (2021)
In order to improve Remaining Useful Life (RUL) prediction accuracy for rolling bearings under defect progressing, the robustness for individual differences and the fluctuation of vibration features are challenging issues. In this research, we propos
Externí odkaz:
https://doaj.org/article/22425214a9a8466e99571a85f4923185
Publikováno v:
Biochemical and Biophysical Research Communications. 621:32-38
Peroxiredoxin 4 (Prdx4) is responsible for the oxidative folding of new proteins that are synthesized in the endoplasmic reticulum (ER). It has recently been suggested that increased ER stress is associated with neurodegenerative diseases, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c179ef827c7ee158274fdd17ddcd05e
https://doi.org/10.1016/j.bbrc.2022.06.096
https://doi.org/10.1016/j.bbrc.2022.06.096
Autor:
Asuka Kono, Manabu Wakamatsu, Yoshihiro Umezawa, Hideki Muramatsu, Hiroki Fujiwara, Dan Tomomasa, Kento Inoue, Keiichiro Hattori, Tetsuo Mitsui, Hidetoshi Takada, Yoshiyuki Minegishi, Yoshiyuki Takahashi, Masahide Yamamoto, Takehiko Mori, Hirokazu Kanegane
Publikováno v:
International Journal of Hematology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b64146d89f183a50ca22cbed96f0360
https://doi.org/10.1007/s12185-023-03613-y
https://doi.org/10.1007/s12185-023-03613-y
Publikováno v:
Learning & Memory. 29:110-119
In hippocampal CA1 neurons of wild-type mice, a short tetanus (15 or 20 pulses at 100 Hz) or a standard tetanus (100 pulses at 100 Hz) to a naive input pathway induces long-term potentiation (LTP) of the responses. Low-frequency stimulation (LFS; 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284973c4ffad13088057e307c4f5a3e2
https://doi.org/10.1101/lm.053542.121
https://doi.org/10.1101/lm.053542.121
Publikováno v:
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 82:1699-1703
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::275e8264b4069ebee55608fe0fb8ef28
https://doi.org/10.3919/jjsa.82.1699
https://doi.org/10.3919/jjsa.82.1699
Autor:
Hiroko Sugiura, Tadayuki Shimada, Keiko Moriya-Ito, Jun-Ichi Goto, Hiroki Fujiwara, Rie Ishii, Hiroshi Shitara, Choji Taya, Satoshi Fujii, Toshiyuki Kobayashi, Okio Hino, Paul F. Worley, Kanato Yamagata
Publikováno v:
J Neurosci
Tuberous sclerosis complex (TSC) is caused by mutations inTsc1orTsc2, whose gene products inhibit the small G-protein Rheb1. Rheb1 activates mTORC1, which may cause refractory epilepsy, intellectual disability, and autism. The mTORC1 inhibitors have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2847e25f5eebcb9105d1c700b5adc285
https://europepmc.org/articles/PMC8944237/
https://europepmc.org/articles/PMC8944237/
Autor:
Yotaro Motomura, Naoki Takezako, Tomoyuki Arimatsu, Takashi Kumagai, Keigo Okada, Tsuyoshi Kato, Hiroki Fujiwara
Publikováno v:
Internal Medicine
Objective Patients with hematological malignancies, particularly those with multiple myeloma, often suffer from pathological vertebral compression fractures (VCFs). Consequent and significant spinal pain and paralysis impair the activities of daily l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022485e57eb4a37ddf0c866ad8c5e086
http://europepmc.org/articles/PMC8112972
http://europepmc.org/articles/PMC8112972
Publikováno v:
Learning & Memory. 27:52-66
In CA1 neurons of guinea pig hippocampal slices, long-term potentiation (LTP) was induced in field excitatory postsynaptic potentials (EPSPs) or population spikes (PSs) by the delivery of high-frequency stimulation (HFS, 100 pulses at 100 Hz) to CA1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5641e0417f77a67439fd2036df5e6e2b
https://doi.org/10.1101/lm.050344.119
https://doi.org/10.1101/lm.050344.119