Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Hiroki FUJIWARA"'
Autor:
Ayako Nogami, Hideki Jose Amemiya, Hiroki Fujiwara, Yoshihiro Umezawa, Shuji Tohda, Toshikage Nagao
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10372 (2024)
FMS-like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML) are associated with poor prognosis and therapy resistance. This study aimed to demonstrate that inhibiting the deubiquitinating enzymes ubiq
Externí odkaz:
https://doaj.org/article/35b1f64a038647e591d18d29b054415f
Publikováno v:
Lubricants, Vol 12, Iss 1, p 13 (2024)
Grease-lubricated rolling bearings transition from the churning phase to the channeling phase. This transition property affects grease life and torque properties. Therefore, the relationship between grease yield stress and grease degradation during o
Externí odkaz:
https://doaj.org/article/c17a143f23ef46eba4e88d97dc25817b
Publikováno v:
IEEE Access, Vol 9, Pp 62642-62652 (2021)
In order to improve Remaining Useful Life (RUL) prediction accuracy for rolling bearings under defect progressing, the robustness for individual differences and the fluctuation of vibration features are challenging issues. In this research, we propos
Externí odkaz:
https://doaj.org/article/22425214a9a8466e99571a85f4923185
Autor:
Hiroki Fujiwara, Yoshihiro Wake, Narumi Hashikawa-Hobara, Kento Makino, Shingo Takatori, Yoshito Zamami, Yoshihisa Kitamura, Hiromu Kawasaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 3, Pp 373-381 (2012)
The endothelium in rat mesenteric vascular beds has been demonstrated to regulate vascular tone by releasing mainly endothelium-derived hyperpolarizing factor (EDHF), which is involved in the activation of K+ channels and gap-junctions. However, it i
Externí odkaz:
https://doaj.org/article/aa34e5cc8581462a9c6832bee613749a
Autor:
Hiroki Fujiwara, Narumi Hashikawa-Hobara, Yoshihiro Wake, Shingo Takatori, Mitsuhiro Goda, Hiroshi Higuchi, Yoshito Zamami, Panot Tangsucharit, Hiromu Kawasaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 3, Pp 260-270 (2012)
Rat mesenteric arteries were maintained by both adrenergic vasoconstrictor nerves and calcitonin gene–related peptide (CGRP) vasodilator nerves. However, functions of these nerves in a pathophysiological state have not fully been analyzed. The use
Externí odkaz:
https://doaj.org/article/88d4e1cf71a34613ab2b90dc78d38c22
Autor:
Hiroki FUJIWARA, Kazuto YAMAUCHI
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 4, Iss 4, Pp 728-738 (2010)
A logarithmic profile is essentially optimal crowning geometry for rolling machine elements such as bearing rollers and raceways. Although some design methods of the profile have been proposed, they do not refer to the tolerance of the geometry requi
Externí odkaz:
https://doaj.org/article/d83aaa42efd445cfb38c765989b4077d
Publikováno v:
Biochemical and Biophysical Research Communications. 621:32-38
Peroxiredoxin 4 (Prdx4) is responsible for the oxidative folding of new proteins that are synthesized in the endoplasmic reticulum (ER). It has recently been suggested that increased ER stress is associated with neurodegenerative diseases, including
Autor:
Asuka Kono, Manabu Wakamatsu, Yoshihiro Umezawa, Hideki Muramatsu, Hiroki Fujiwara, Dan Tomomasa, Kento Inoue, Keiichiro Hattori, Tetsuo Mitsui, Hidetoshi Takada, Yoshiyuki Minegishi, Yoshiyuki Takahashi, Masahide Yamamoto, Takehiko Mori, Hirokazu Kanegane
Publikováno v:
International Journal of Hematology.
Publikováno v:
Learning & Memory. 29:110-119
In hippocampal CA1 neurons of wild-type mice, a short tetanus (15 or 20 pulses at 100 Hz) or a standard tetanus (100 pulses at 100 Hz) to a naive input pathway induces long-term potentiation (LTP) of the responses. Low-frequency stimulation (LFS; 100
Publikováno v:
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 82:1699-1703