Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Hiroki, Hamada"'
Autor:
Takahiro Nakayama, Akash K. Singh, Toshiyuki Fukutomi, Noriyuki Uchida, Yasuo Terao, Hiroki Hamada, Takahiro Muraoka, Eswaramoorthy Muthusamy, Tapas K. Kundu, Kimio Akagawa
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114101- (2024)
Summary: Syntaxin-1A (stx1a) repression causes a neurodevelopmental disorder phenotype, low latent inhibition (LI) behavior, by disrupting 5-hydroxytryptaminergic (5-HTergic) systems. Herein, we discovered that lysine acetyltransferase (KAT) 3B incre
Externí odkaz:
https://doaj.org/article/7082df1e29b6458ba0cf338791935a20
Autor:
Hiroki Hamada, Toshiaki Uemoto, Yoshitaka Tanaka, Yuki Honda, Keiichi Kitajima, Tetsuya Umeda, Atsushi Kawakami, Minori Shinya, Koichi Kawakami, Koji Tamura, Gembu Abe
Publikováno v:
Zoological Letters, Vol 5, Iss 1, Pp 1-12 (2019)
Abstract Background Teleost paired fins are composed of two endoskeletal domains, proximal and distal radials, and an exoskeletal domain, the fin ray. The zebrafish pectoral fin displays elaborately patterned radials along the anteroposterior (AP) ax
Externí odkaz:
https://doaj.org/article/f7affc3195384472855d0cc694bc45f2
Autor:
Ikuo Nakanishi, Yoshimi Shoji, Kei Ohkubo, Megumi Ueno, Kei Shimoda, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, Hiroki Hamada
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 340 (2022)
Pterostilbene (PTS), a methylated analog of resveratrol (RSV), has recently attracted much attention due to its enhanced bioavailability compared to RSV. However, little is known about the radical-scavenging mechanism of PTS. In this study, we invest
Externí odkaz:
https://doaj.org/article/5739f46030c74169b3ae230cad6448a6
Autor:
Suzuka, Miura, Eri, Oyanagi, Chihiro, Watanabe, Hiroki, Hamada, Takafumi, Aoki, Michael J, Kremenik, Hiromi, Yano
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 86:1423-1430
Fatigue is accompanied by a decrease in physical activity or malaise, and might be reduced by acetyl-L-carnitine (ALC) administration. The purpose of this study was to investigate the preventive effects of ALC on Poly I:C-induced sickness behavior in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32e6a65f92b6d26fbc06cc4ba44ed80
https://doi.org/10.1093/bbb/zbac132
https://doi.org/10.1093/bbb/zbac132
Publikováno v:
Nanomaterials, Vol 11, Iss 2, p 335 (2021)
A transdermal drug delivery system (TDDS) is a method that provides drug adsorption via the skin. TDDS could replace conventional oral administration and blood administration because it is easily accessible. However, it is still difficult to design e
Externí odkaz:
https://doaj.org/article/4891d957c5db4682859ce571c4f47e8e
Autor:
Chihiro Watanabe, Eri Oyanagi, Takafumi Aoki, Hiroki Hamada, Masato Kawashima, Takashi Yamagata, Kremenik, Michel J., Hiromi Yano
Publikováno v:
Bioscience, Biotechnology & Biochemistry; Nov2023, Vol. 87 Issue 11, p1407-1419, 13p
Autor:
Rakesh Maharjan, Yohta Fukuda, Taisuke Nakayama, Toru Nakayama, Hiroki Hamada, Shin-ichi Ozaki, Tsuyoshi Inoue
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:379-389
Capsaicinoids are phenolic compounds that have health benefits. However, the pungency and poor water solubility of these compounds limit their exploitation. Glycosylation is a powerful method to improve water solubility and reduce pungency while pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2657dc79e0bb0326ba067ae91e9699ce
https://doi.org/10.1107/s2059798322000869
https://doi.org/10.1107/s2059798322000869
Autor:
Takahiro Nakayama, Akash K. Singh, Toshiyuki Fukutomi, Noriyuki Uchida, Yasuo Terao, Hiroki Hamada, Takahiro Muraoka, Eswaramoorthy E. Muthusamy, Tapas K. Kundu, Kimio Akagawa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::356fd847fa05c8d2d68896fc378d3aa4
https://doi.org/10.2139/ssrn.4459565
https://doi.org/10.2139/ssrn.4459565
Publikováno v:
Molecules, Vol 25, Iss 6, p 1437 (2020)
Oxyresveratrol and gnetol are naturally occurring stilbene compounds, which have diverse pharmacological activities. The water-insolubility of these compounds limits their further pharmacological exploitation. The glycosylation of bioactive compounds
Externí odkaz:
https://doaj.org/article/172a5dc0d00445419e81917162ec444c
Autor:
Yuya Fujitaka, Hiroki Hamada, Daisuke Uesugi, Atsuhito Kuboki, Kei Shimoda, Takafumi Iwaki, Yuya Kiriake, Tomohiro Saikawa
Publikováno v:
Molecules, Vol 24, Iss 16, p 2975 (2019)
Daidzein is a common isoflavone, having multiple biological effects such as anti-inflammation, anti-allergy, and anti-aging. α-Tocopherol is the tocopherol isoform with the highest vitamin E activity including anti-allergic activity and anti-cancer
Externí odkaz:
https://doaj.org/article/ab2d621b0ae24bc3a2266afd373b3abb