Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hirokazu Sugimoto"'
Autor:
Mizuyo Nakamura, Hiroki Nagase, Kyoko Fujiwara, Kiriko Hiraoka, Toshinori Ozaki, Hirokazu Sugimoto, Meixiang Sang, Hiroyuki Yoda
Publikováno v:
The Febs Journal
Although runt-related transcription factor 2 (RUNX2) is known to be an essential key transcription factor for osteoblast differentiation and bone formation, RUNX2 also plays a pivotal role in the regulation of p53-dependent DNA damage response. In th
Autor:
Koji Oda, Kosuke Okada, Hirotoshi Utsunomiya, Keiko Taguchi, Kaoru Ishizaki, Nobuharu Goto, Hirokazu Sugimoto, Junichi Shoda, Jonathan M. Maher, Masayuki Yamamoto, Tetsuro Ishii, Yoshimi Inoue, Eiji Warabi, Makio Ohtsuki
Publikováno v:
Biochemical and Biophysical Research Communications. 389:431-436
The transcription factor Nrf2 is a key regulator for hepatic induction of detoxifying enzymes, antioxidative stress genes and Mrp efflux transporters. We aimed to investigate whether Nrf2 activation counteracts liver injury associated with cholestasi
Publikováno v:
Journal of Structural and Construction Engineering (Transactions of AIJ). 67:141-148
Autor:
Hirokazu Sugimoto, Yoshiaki Maru, Atsushi Takatori, Hiroki Nagase, Toshikazu Bando, Tadamichi Denda, Takayoshi Watanabe, Kyoko Fujiwara, Nobuko Koshikawa, Allan Balmain, Hiroyuki Yoda, Takahiro Inoue, Hiroshi Sugiyama, Kiriko Hiraoka, Toshinori Ozaki, Ken-ichi Shinohara, Rhys Dylan Taylor
Publikováno v:
Nature communications. 6
Despite extensive efforts to target mutated RAS proteins, anticancer agents capable of selectively killing tumour cells harbouring KRAS mutations have remained unavailable. Here we demonstrate the direct targeting of KRAS mutant DNA using a synthetic
Autor:
Fumio Ohtake, Satoshi Yamada, Yuka Matsumoto, Saburo Matsuoka, Hirokazu Sugimoto, Hiroshi Akiyama
Publikováno v:
Journal of Structural and Construction Engineering (Transactions of AIJ). 64:105-112
Autor:
Hiroshi Takahashi, Junichi Shoda, Hirokazu Sugimoto, Tetsuro Ishii, Naohiro Gotoh, Katsutoshi Tokushige, Kosuke Okada, Masaki Horie, Hirotoshi Utsunomiya, Eiji Warabi, Masayuki Yamamoto, Etsuko Hashimoto
Publikováno v:
Journal of gastroenterology. 48(5)
The transcription factor nuclear factor-E2-related factor-2 (Nrf2) inhibits lipid accumulation and oxidative stress in the liver by interfering with lipogenic pathways and inducing antioxidative stress genes.The involvement of Nrf2 in defense against
Autor:
Tetsuya Ueda, Tetsuro Ishii, Ichinosuke Hyodo, Toru Yanagawa, Kazunori Ishige, Keiko Taguchi, Masayuki Yamamoto, Eiji Warabi, Kosuke Okada, Hirokazu Sugimoto, Akira Nakahara, Junichi Shoda
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 298(2)
Oxidative stress is a critical mediator in liver injury of steatohepatitis. The transcription factor Nrf2 serves as a cellular stress sensor and is a key regulator for induction of hepatic detoxification and antioxidative stress systems. The involvem
Autor:
Dong Pyo Kim, Fumio Miyazaki, Yukihisa Tanaka, Junichi Ieda, Hirokazu Sugimoto, Nobuhito Mori, Tomoya Usui, Yasuhiro Masutani, Ryouhei Fujimoto, Daisuke Sekimori, Masaya Enomoto, Tetsuhiro Maeda, Wataru Matsui, Osamu Miyake
Publikováno v:
RoboCup 2001: Robot Soccer World Cup V ISBN: 9783540439127
RoboCup
RoboCup
The Team OMNI has developed a robot system with omni-directional vision and omni-directional mobility according to the rule of the RoboCup Small Size League. This paper describes the hardware configuration, software configuration, and simulator of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c69099fde1bede105ccc91f44ed7ad
https://doi.org/10.1007/3-540-45603-1_93
https://doi.org/10.1007/3-540-45603-1_93