Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hirokazu Sakan"'
Autor:
Hirokazu Sakan, Kimihiko Nakatani, Osamu Asai, Akihiro Imura, Tomohiro Tanaka, Shuhei Yoshimoto, Noriyuki Iwamoto, Norio Kurumatani, Masayuki Iwano, Yo-Ichi Nabeshima, Noboru Konishi, Yoshihiko Saito
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86301 (2014)
Renal α-Klotho (α-KL) plays a fundamental role as a co-receptor for fibroblast growth factor 23 (FGF23), a phosphaturic hormone and regulator of 1,25(OH)2 vitamin D3 (1,25VitD3). Disruption of FGF23-α-KL signaling is thought to be an early hallmar
Externí odkaz:
https://doaj.org/article/3d3fd9c6d4e5457bb01a4a188fb49e39
Autor:
Yoshihiko Saito, Satoshi Somekawa, Kenichi Ishigami, Yukiji Takeda, Hiroyuki Kawata, Shinichi Fujimoto, Hirokazu Sakan, Manabu Horii, Shiro Uemura, Satoshi Okayama
Publikováno v:
Internal Medicine. 50:1747-1751
Echocardiography and magnetic resonance imaging revealed biventricular non-compaction cardiomyopathy with ventricular (VSD) and atrial (ASD) septal defects in an unconscious, 23-year-old hypoxemic man. Doppler echocardiography showed a left-to-right
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae104926c7049c0bc5cf5086c1bef47
https://doi.org/10.2169/internalmedicine.50.5290
https://doi.org/10.2169/internalmedicine.50.5290
Autor:
Yoshihiko Saito, Masato Nose, Ken-ichi Samejima, Miho Terada, Kimihiko Nakatani, Shuhei Yoshimoto, Masayuki Iwano, Hitoshi Hasegawa, Hirokazu Sakan, Osamu Asai
Publikováno v:
American Journal of Physiology-Renal Physiology. 299:F207-F216
Fractalkine (Fkn) is expressed on injured endothelial cells and is a membrane-bound chemokine that attracts cells expressing its receptor, CX3CR1, including CD16+monocytes (CD16+Mos). To clarify the role played by Fkn in the development of glomerular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8aed83b578a40d1f2832629e5b971b2
https://doi.org/10.1152/ajprenal.00482.2009
https://doi.org/10.1152/ajprenal.00482.2009
Autor:
Hideo Shiiki, Koji Harada, Yasuhiro Akai, Yoshihiko Saito, Kimihiko Nakatani, Ken-ichi Samejima, Miho Terada, Osamu Asai, Masayuki Iwano, Shuhei Yoshimoto, Hirokazu Sakan, Masato Nose
Publikováno v:
American Journal of Kidney Diseases. 50:47-58
Background Fractalkine (Fkn) is a chemokine that affects cells expressing its receptor, CX3CR1, including CD16-positive (CD16 + ) monocytes/macrophages (CD16 + Mos). The relationship of levels of glomerular Fkn expression and infiltration by CD16 + M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89650ebcb04c869a913d30198c54ed0d
https://doi.org/10.1053/j.ajkd.2007.04.012
https://doi.org/10.1053/j.ajkd.2007.04.012
Autor:
Miho Terada, Noboru Konishi, Hirokazu Sakan, Masayuki Iwano, Kimihiko Nakatani, Shuhei Yoshimoto, Osamu Asai, Masato Nose
Publikováno v:
Modern rheumatology. 24(5)
To examine the role played by E-selectin in bystander IgM-mediated modification of glomerular lesions in experimental lupus nephritis.Experimental lupus SCID mice were induced by an intraperitoneal injection of clone 7B6.8, which was derived from a M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6759cb0399f6a591498a5a7ba1e87e6d
https://pubmed.ncbi.nlm.nih.gov/24372297
https://pubmed.ncbi.nlm.nih.gov/24372297
Autor:
Osamu Asai, Noboru Konishi, Yoshihiko Saito, Masayuki Iwano, Masato Nose, Shuhei Yoshimoto, Kimihiko Nakatani, Hirokazu Sakan, Miho Terada
Publikováno v:
Immunity, Inflammation and Disease
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that causes inflammatory tissue damage, including lupus nephritis and vasculitis. Local generation of adhesion molecules and expression of their ligands on inflammatory cells appears
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab96e4c2c3860940ffb47cfcafcb06b1
https://pubmed.ncbi.nlm.nih.gov/25400916
https://pubmed.ncbi.nlm.nih.gov/25400916
Autor:
Hirokazu, Sakan, Kimihiko, Nakatani, Osamu, Asai, Masaru, Matsui, Masayuki, Iwano, Yoshihiko, Saito
Publikováno v:
Nihon Jinzo Gakkai shi. 54(5)
A 69-year-old man with a history of hypertension was admitted to our hospital because of proteinuria, renal dysfunction, and both purpura and edema in the lower extremities. Laboratory data on admission revealed proteinuria (3.4 g/day), microscopic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15fc3f065c5f819766703f6bcc10b6f6
https://pubmed.ncbi.nlm.nih.gov/22991843
https://pubmed.ncbi.nlm.nih.gov/22991843
Autor:
Osamu Asai, Yoshihiko Saito, Yasuhiro Akai, Masayuki Iwano, Yukinari Yamaguchi, Masaru Matsui, Masao Toyoda, Shuhei Yoshimoto, Hirokazu Sakan, Daisuke Suzuki, Ken-ichi Samejima, Kimihiko Nakatani
Publikováno v:
Nephron. Clinical practice. 120(1)
Backgrounds/Aims: We previously reported that fibroblast-specific protein 1 (FSP1) is a marker of epithelial-mesenchymal transition (EMT) in tubulointerstitial fibrosis. The EMT-like changes observed in podocytes are reportedly associated with podocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ee03ab57da2304e545a2115065a078
https://pubmed.ncbi.nlm.nih.gov/22126861
https://pubmed.ncbi.nlm.nih.gov/22126861
Autor:
Fengzhi Liu, Makoto Kanoh, Kohsuke Sumita, Yoshihiro Asano, Saho Maruyama, Teruyoshi Uetani, Hirokazu Sakan
Publikováno v:
International immunology. 14(6)
Pathogenic infections lead to activation of innate immunity followed by induction of a type 1 T cell subset and, therefore, provide a good model to evaluate when T cells commit to type 1 T cells. Here we show a two-step mechanism of T cell subset com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29363602c596bcbdc4b2fedfd7067781
https://pubmed.ncbi.nlm.nih.gov/12039908
https://pubmed.ncbi.nlm.nih.gov/12039908
Autor:
Tomohiro Tanaka, Osamu Asai, Akihiro Imura, Kimihiko Nakatani, Masayuki Iwano, Shuhei Yoshimoto, Hirokazu Sakan, Noriyuki Iwamoto, Yo-ichi Nabeshima, Noboru Konishi, Norio Kurumatani, Yoshihiko Saito
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86301 (2014)
PLoS ONE
PLoS ONE
Renal α-Klotho (α-KL) plays a fundamental role as a co-receptor for fibroblast growth factor 23 (FGF23), a phosphaturic hormone and regulator of 1,25(OH)2 vitamin D3 (1,25VitD3). Disruption of FGF23-α-KL signaling is thought to be an early hallmar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a33cef5640126fd5ef2de0cc8a4179
https://doi.org/10.1371/journal.pone.0086301
https://doi.org/10.1371/journal.pone.0086301