Zobrazeno 1 - 10
of 533
pro vyhledávání: '"Hirokazu Fukui"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Chronic pancreatitis (CP) is a disease characterized by the inflammation and destruction of pancreatic tissue, leading to the replacement of functional tissue with fibrotic tissue. The regenerating gene (Reg) family proteins have recently be
Externí odkaz:
https://doaj.org/article/6cf9a13a99a64b0b8d9aa92a6763e5f9
Autor:
Toshihiko Tomita, Hirokazu Fukui, Takuya Okugawa, Takashi Nakanishi, Masatoshi Mieno, Keisuke Nakai, Hirotsugu Eda, Yoshitaka Kitayama, Tadayuki Oshima, Shinichiro Shinzaki, Hiroto Miwa
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 10, p 3368 (2023)
Diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms are distressing for patients with quiescent Crohn’s disease (qCD) and worsen their quality of life. In the present study, we assessed the effect of the probiotic Bifidobacterium bi
Externí odkaz:
https://doaj.org/article/61a3190690084527be406ba692c3cdf6
Autor:
Jiro Watari, Toshihiko Tomita, Katsuyuki Tozawa, Tadayuki Oshima, Hirokazu Fukui, Hiroto Miwa
Publikováno v:
Gut and Liver, Vol 14, Iss 3, Pp 281-290 (2020)
Whether Helicobacter pylori eradication actually reduces the risk of metachronous gastric cancer (MGC) development remains a controversial question. In this review, we addressed this topic by reviewing the results of clinical investigations and molec
Externí odkaz:
https://doaj.org/article/b085e84c07e048e48788eca94a282beb
Autor:
Toshihiko Tomita, Hirokazu Fukui, Daisuke Morishita, Sumire Mori, Tadayuki Oshima, Shinichiro Shinzaki, Hiroto Miwa
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 23, p 6882 (2022)
Patients with quiescent inflammatory bowel disease (IBD) frequently suffer diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms, such as abdominal pain or stool irregularities. Here, we assessed the effect of ramosetron, a serotonin ty
Externí odkaz:
https://doaj.org/article/2c52a6439bcf49dcb7d9d8f29c56eea7
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 14, p 4246 (2022)
This study aimed to evaluate the relationship of esophageal epithelial permeability with mast cell infiltration and IgG4 deposits as well as chemokine levels in eosinophilic esophagitis (EoE) patients before and after treatment. Biopsies from control
Externí odkaz:
https://doaj.org/article/578b5c3da3794df1b980e58802d80d6a
Autor:
Nobuhiko Ebisutani, Hirokazu Fukui, Heihachiro Nishimura, Takashi Nakanishi, Kenki Morimoto, Shiho Itou, Ayumi Nakamura, Mizuki Masutani, Mika Hori, Toshihiko Tomita, Tadayuki Oshima, Emiko Kasahara, Atsuo Sekiyama, Hiroto Miwa
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Psychological stress is deeply involved in the pathophysiology of not only mental illness but also functional gastrointestinal disorders. In the present study, we examined the relationship between psychological stress and abnormality of stool propert
Externí odkaz:
https://doaj.org/article/4edf0aa2c65c498fb9ba4d69e61b7bcf
Autor:
Sota Aono, Toshihiko Tomita, Katsuyuki Tozawa, Daisuke Morishita, Keisuke Nakai, Takuya Okugawa, Masashi Fukushima, Tadayuki Oshima, Hirokazu Fukui, Hiroto Miwa
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 9, p 2342 (2022)
The subtypes of functional dyspepsia (FD) differ depending on whether the Rome III criteria or the Rome IV criteria are used. We investigated the ability to diagnose FD patients using the Rome III and IV criteria. The subtypes of FD were evaluated us
Externí odkaz:
https://doaj.org/article/827eab322903496299ea26195f8f2fe3
Autor:
Ioana Neagoe, Chang Liu, Alexander Stumpf, Yanmei Lu, Dongping He, Ross Francis, Jun Chen, Paul Reynen, Moulay Hicham Alaoui-Ismaili, Hirokazu Fukui
Publikováno v:
Stem Cell Research, Vol 28, Iss , Pp 105-114 (2018)
Abnormal signaling pathways mediated by N-methyl-d-aspartate receptors (NMDARs) have been implicated in the pathogenesis of various CNS disorders and have been long considered as promising points of therapeutic intervention. However, few efforts have
Externí odkaz:
https://doaj.org/article/173841831bd44134a7e86a96a12cf370
Autor:
Hiroo Sei, Toshihiko Tomita, Keisuke Nakai, Kumiko Nakamura, Akio Tamura, Yoshio Ohda, Tadayuki Oshima, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
Publikováno v:
Case Reports in Gastroenterology, Vol 12, Iss 1, Pp 189-193 (2018)
Transanal rectal foreign body implies that a foreign body has been inserted transanally due to sexual orientation or other reasons and cannot be removed. Such cases require emergency measures because foreign bodies often present difficulties in manua
Externí odkaz:
https://doaj.org/article/6c41f02b73ea4511bb672b0254cc5a5d
Autor:
Ko Miura, Tadayuki Oshima, Akio Tamura, Ken Hara, Takuya Okugawa, Masashi Fukushima, Toshihiko Tomita, Hirokazu Fukui, Hiroto Miwa
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 23, p 5704 (2021)
Early detection of gastric cancer is important. However, rapid growth of gastric cancers that cannot be resected endoscopically occurs even with periodic check-ups. Accordingly, we assessed factors associated with the speed of gastric cancer growth b
Externí odkaz:
https://doaj.org/article/1f9a1a38653f488b9375a249193ec256