Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Hirokazu, Sadahiro"'
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy
Autor:
Soniya Bastola, Marat S. Pavlyukov, Daisuke Yamashita, Sadashib Ghosh, Heejin Cho, Noritaka Kagaya, Zhuo Zhang, Mutsuko Minata, Yeri Lee, Hirokazu Sadahiro, Shinobu Yamaguchi, Svetlana Komarova, Eddy Yang, James Markert, Louis B. Nabors, Krishna Bhat, James Lee, Qin Chen, David K. Crossman, Kazuo Shin-Ya, Do-Hyun Nam, Ichiro Nakano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Intratumoural spatial heterogeneity is crucial to enhance therapeutic resistance in glioblastoma. Here, the authors show a paracrine signaling mechanism where glioblastoma-initiating cells located in the tumour edge elevate their malignancy by intera
Externí odkaz:
https://doaj.org/article/07b5f2bb5b4a4838a58f12fd8d7ba3c5
Autor:
Hirokazu SADAHIRO1 sadapiro@yamaguchi-u.ac.jp, Kazutaka SUGIMOTO1, Fumiaki OKA1, Mototsugu SHIMOKAWA2, Hideyuki ISHIHARA1
Publikováno v:
Neurosonology: Official Journal of Japan Academy of Neurosonology. 2022, Vol. 35 Issue 3, p104-109. 6p.
Autor:
Akinori Inamura, MD, Sadahiro Nomura, MD, PhD, Hirokazu Sadahiro, MD, PhD, Hirochika Imoto, MD, PhD, Hideyuki Ishihara, MD, PhD, Michiyasu Suzuki, MD, PhD
Publikováno v:
Interdisciplinary Neurosurgery, Vol 9, Iss , Pp 64-67 (2017)
Objective: The vagal nerve (VN) can be located either dorsal or ventral to the common carotid artery (CCA). We analyzed the correlation between patient age and the depth of the left VN, assessed if patient age is a reliable predictor of VN location,
Externí odkaz:
https://doaj.org/article/d22ab0f074ff4f969eb0fba259f9611f
Autor:
Ichiro Nakano, Lyse A. Norian, Burt Nabors, L. James Lee, Mitsutoshi Nakada, Biplab DasGupta, Evan W. Newell, Xinghua Lu, Dolores Hambardzumyan, Sung-Hak Kim, Jun Wang, Svetlana Komarova, Hebaallah Alsheikh, Shinobu Yamaguchi, Soniya Bastola, Suojun Zhang, Hemragul Sabit, Takuya Furuta, Yannick Simoni, Songjian Lu, Zhihong Chen, Rishi Chhipa, Junfeng Shi, Hai Yu, Mutsuko Minata, Justin T. Gibson, Kyung-Don Kang, Hirokazu Sadahiro
Supplementary Figure S3. PROS1 is located in GSCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573ca18e30217544490b554a28a83f69
https://doi.org/10.1158/0008-5472.22416537.v1
https://doi.org/10.1158/0008-5472.22416537.v1
Autor:
Ichiro Nakano, Lyse A. Norian, Burt Nabors, L. James Lee, Mitsutoshi Nakada, Biplab DasGupta, Evan W. Newell, Xinghua Lu, Dolores Hambardzumyan, Sung-Hak Kim, Jun Wang, Svetlana Komarova, Hebaallah Alsheikh, Shinobu Yamaguchi, Soniya Bastola, Suojun Zhang, Hemragul Sabit, Takuya Furuta, Yannick Simoni, Songjian Lu, Zhihong Chen, Rishi Chhipa, Junfeng Shi, Hai Yu, Mutsuko Minata, Justin T. Gibson, Kyung-Don Kang, Hirokazu Sadahiro
Glioblastoma (GBM) is a lethal disease with no effective therapies available. We previously observed upregulation of the TAM (Tyro-3, Axl, and Mer) receptor tyrosine kinase family member AXL in mesenchymal GBM and showed that knockdown of AXL induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec6fcbf116b99d5d03a35039d8bbe9a
https://doi.org/10.1158/0008-5472.c.6509577.v1
https://doi.org/10.1158/0008-5472.c.6509577.v1
Autor:
Ichiro Nakano, Lyse A. Norian, Burt Nabors, L. James Lee, Mitsutoshi Nakada, Biplab DasGupta, Evan W. Newell, Xinghua Lu, Dolores Hambardzumyan, Sung-Hak Kim, Jun Wang, Svetlana Komarova, Hebaallah Alsheikh, Shinobu Yamaguchi, Soniya Bastola, Suojun Zhang, Hemragul Sabit, Takuya Furuta, Yannick Simoni, Songjian Lu, Zhihong Chen, Rishi Chhipa, Junfeng Shi, Hai Yu, Mutsuko Minata, Justin T. Gibson, Kyung-Don Kang, Hirokazu Sadahiro
Supplementary figure legends and materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44adf639c97046bff84e70fe18709b9c
https://doi.org/10.1158/0008-5472.22416522.v1
https://doi.org/10.1158/0008-5472.22416522.v1
Autor:
Reo Kawano, Kazutaka Sugimoto, Fumiaki Oka, Akiko Kawano, Michiyasu Suzuki, Hirokazu Sadahiro, Sadahiro Nomura, Hideyuki Ishihara, Takao Inoue
Publikováno v:
Neurocritical Care. 35:91-99
Delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH) remains an important problem with a complex pathophysiology. We used data from a single-center randomized trial to assess the effect of a phosphodiesterase inhibitor, cilo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621592efb7e6b1fd101dc7c8818a63aa
https://doi.org/10.1007/s12028-021-01330-0
https://doi.org/10.1007/s12028-021-01330-0
Publikováno v:
Neurosonology. 34:138-141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2aba77a5e3e010276b841109a11c923
https://doi.org/10.2301/neurosonology.34.138
https://doi.org/10.2301/neurosonology.34.138
Autor:
Aya Ishii, Tokuhiro Kimura, Hirokazu Sadahiro, Hiroo Kawano, Keiyo Takubo, Michiyasu Suzuki, Eiji Ikeda
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147366 (2016)
BACKGROUND:Characterization of the niches for stem-like tumor cells is important to understand and control the behavior of glioblastomas. Cell-cycle quiescence might be a common mechanism underlying the long-term maintenance of stem-cell function in
Externí odkaz:
https://doaj.org/article/57b114c98ba7467f9e1cf3ac7ab2c023
Autor:
Yuki Yasumoto, Hirofumi Miyazaki, Linda Koshy Vaidyan, Yoshiteru Kagawa, Majid Ebrahimi, Yui Yamamoto, Masaki Ogata, Yu Katsuyama, Hirokazu Sadahiro, Michiyasu Suzuki, Yuji Owada
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147717 (2016)
Cellular metabolic changes, especially to lipid metabolism, have recently been recognized as a hallmark of various cancer cells. However, little is known about the significance of cellular lipid metabolism in the regulation of biological activity of
Externí odkaz:
https://doaj.org/article/e43e0ae8db5d4b62bd909e1f74fbbb68