Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hirokazu, Kambara"'
Autor:
Hiroyuki Nakashima, Masafumi Hiramatsu, Tomohito Hishikawa, Koji Tokunaga, Hirokazu Kambara, Kenji Sugiu, Naoya Kidani, Kazuki Kobayashi, Kaoru Terasaka, Isao Date
Publikováno v:
Acta neurochirurgica. 164(2)
Background The patients with ruptured vertebral artery dissecting aneurysm (rVADA) should be treated as early as possible because VADA carries extremely high risk of rebleeding in the acute phase. We have established a mobile endovascular strategy fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0daad02aefcef7af379e06a5373def1a
https://pubmed.ncbi.nlm.nih.gov/34146152
https://pubmed.ncbi.nlm.nih.gov/34146152
Autor:
Tomotsugu Ichikawa, E. Antonio Chiocca, Manabu Onishi, Mamoru Ouchida, Satoshi Inoue, Seiji Tamaru, Tomoko Maruo, Isao Date, Kazuhiko Kurozumi, Kenji Shimizu, Hirokazu Kambara, Koichi Yoshida, Hirotaka Kanzaki
Publikováno v:
Neuropathology. 33:264-275
One of the insidious biological features of gliomas is their potential to extensively invade normal brain tissue, yet molecular mechanisms that dictate this locally invasive behavior remain poorly understood. To investigate the molecular basis of inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5fdfa2f30f8a312d5413f1efd43e19
https://doi.org/10.1111/j.1440-1789.2012.01361.x
https://doi.org/10.1111/j.1440-1789.2012.01361.x
Autor:
Takashi Tamiya, Hirokazu Kambara, Eiji Iwado, Hiroshi Kosaka, Tomotsugu Ichikawa, Isao Date, Seiji Kondo, Shinji Otsuka
Publikováno v:
Neuropathology. 32:638-646
Accumulating evidence indicates that VEGF and matrix metalloproteinase-9 (MMP-9) play a central role in the development of peritumoral brain edema (PTBE) associated with human brain tumors. However, the roles of these proteins, particularly of MMP-9,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1fa104f06a438291f265efc99ea844a
https://doi.org/10.1111/j.1440-1789.2012.01312.x
https://doi.org/10.1111/j.1440-1789.2012.01312.x
Autor:
Taro Shuin, Naoto Sakai, Tomotsugu Ichikawa, Hirokazu Kambara, Shuji Hamazaki, Yoshiro Otsuki, Isao Date, Takafumi Wataya
Publikováno v:
Brain Tumor Pathology. 28:279-284
We report a case of a cerebellar tumor consisting of a mixed germ cell tumor (GCT) and a hemangioblastoma. A 22-year-old man presented with myoclonus and cerebellar ataxia. Magnetic resonance imaging showed a tumor mass in the left cerebellar hemisph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8789065f57c6095fef4effcb7f9a391
https://doi.org/10.1007/s10014-011-0031-7
https://doi.org/10.1007/s10014-011-0031-7
Autor:
Yasuyuki Miyoshi, Tomotsugu Ichikawa, Takashi Agari, Kazuhiko Kurozumi, Takao Yasuhara, Koji Tokunaga, Hirokazu Kambara, Isao Date, Shigeki Ono
Publikováno v:
The Open Neurosurgery Journal. 2:4-7
Parkinsonism related to brain tumor is reviewed with the presentation of our case. Neurosurgeons or neurolo- gists know that some patients with brain tumor present parkinsonism, although further enlightenment is required. The mechanisms are divided i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11e1e333d732b6c1354dcae9b922247
https://doi.org/10.2174/1876529700902010004
https://doi.org/10.2174/1876529700902010004
Autor:
Rebecca A. Gillespie, E. Antonio Chiocca, Hirokazu Kambara, Nancy M. Sawtell, Greg Stroup, Timothy P. Cripe, Yonatan Y. Mahller, Margaret H. Collins, Mark A. Currier
Publikováno v:
Molecular Therapy. 16(5):879-885
Oncolytic herpes simplex virus (oHSV) mutants are under development as anticancer therapeutics. One such vector, rRp450, is ICP6-deleted and expresses a prodrug enzyme for cyclophosphamide (CPA) (rat CYP2B1). Little is known about rRp450's toxicity p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8742f311504dcc8f92789902d305f285
Publikováno v:
Cancer Research. 65:2832-2839
Oncolytic herpes simplex virus-1 (HSV-1) mutants possessing mutations in the ICP34.5 and ICP6 genes have proven safe through clinical trials. However, ICP34.5-null viruses may grow poorly in cells due to their inability to prevent host-cell shut-off
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f774f2e851168074dd2f88ed21e99bc1
https://doi.org/10.1158/0008-5472.can-04-3227
https://doi.org/10.1158/0008-5472.can-04-3227
Autor:
Hirofumi Hamada, Tomotsugu Ichikawa, Takashi Ohmoto, Yasuhiro Ono, Hirokazu Kambara, Takashi Tamiya, Shinji Ohtsuka, Yoshiaki Adachi, Kinya Terada
Publikováno v:
Cancer Gene Therapy. 9:840-845
Radiation therapy is an established modality for the treatment of malignant gliomas. Several reports have shown the advantage of additional radiation in combination with gene therapy. In this study, we investigated the ability of radiation therapy to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb1b3b8bc6ac71f2535f18b50489a8e
https://doi.org/10.1038/sj.cgt.7700506
https://doi.org/10.1038/sj.cgt.7700506
Autor:
Yasuhiro Ono, Kinya Terada, Mamoru Ouchida, Takashi Ohmoto, Shigeru Daido, Hirokazu Kambara, Hiroaki Tanaka, Kenji Shimizu, Sachio Ito, Kengo Matsumoto, Takashi Tamiya
Publikováno v:
Journal of Neuro-Oncology. 58:107-114
We thoroughly examined loss of heterozygosity (LOH) around three candidate tumor suppressor genes on chromosome 10q to determine whether LOH of each tumor suppressor gene is associated with the previously defined clinical prognostic indices. We also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950d6c56cdccbcbf2c0a0ea6c02d001d
https://doi.org/10.1023/a:1016017711033
https://doi.org/10.1023/a:1016017711033
Autor:
Tomoko, Maruo, Tomotsugu, Ichikawa, Hirotaka, Kanzaki, Satoshi, Inoue, Kazuhiko, Kurozumi, Manabu, Onishi, Koichi, Yoshida, Hirokazu, Kambara, Mamoru, Ouchida, Kenji, Shimizu, Seiji, Tamaru, E Antonio, Chiocca, Isao, Date
Publikováno v:
Neuropathology : official journal of the Japanese Society of Neuropathology. 33(3)
One of the insidious biological features of gliomas is potential to invade normal brain tissue extensively, yet molecular mechanisms that dictate this locally invasive behavior remain poorly understood. To investigate the molecular basis of invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f80c12c8be8ce44bb5eca1d9af68cdf4
https://pubmed.ncbi.nlm.nih.gov/23116197
https://pubmed.ncbi.nlm.nih.gov/23116197