Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hirokatsu Takatsu"'
Publikováno v:
Molecules, Vol 27, Iss 4, p 1425 (2022)
Anti-rheumatoid arthritis (RA) effects of α-tocopherol (α-T) have been shown in human patients in a double-blind trial. However, the effects of α-T and its derivatives on fibroblast-like synoviocytes (FLS) during the pathogenesis of RA remain uncl
Externí odkaz:
https://doaj.org/article/84775a1e8926413fbbb4351ff535757d
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 281 (2022)
Many neurodegenerative disorders, including Alzheimer’s disease (AD), are strongly associated with the accumulation of oxidative damage. Transgenic animal models are commonly used to elucidate the pathogenic mechanism of AD. Beta amyloid (Aβ) and
Externí odkaz:
https://doaj.org/article/e52dfa1541e84cd3bda3015d8c12500c
Autor:
Hirokatsu Takatsu, Yoshinori Aoki, Hayami Uchiumi, Shogo Endo, Yugo Kato, Shuichi Yanai, Koji Fukui, Ryo Usami
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Obesity induces severe disorders such as type 2 diabetes and cardiovascular events, and the number of people with obesity is increasing all over the world. Furthermore, it is possible that obesity increases the risk of cognitive dysfunction via the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c4b84a19760860a5dd4f9a8481a2f0
https://doi.org/10.3164/jcbn.21-10
https://doi.org/10.3164/jcbn.21-10
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
To define whether tocotrienol (T-3) improves cognitive deficit during aging, effect of T-3 on learning and memory functions of aged rats was assessed. It was found that T-3 markedly counteracts the decline in learning and memory function in aged rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095f339ee131e46b71d26f36f8eec5a1
https://doi.org/10.3164/jcbn.15-52
https://doi.org/10.3164/jcbn.15-52
Autor:
Shiro Urano, Koji Fukui, Tatsuki Honjo, Hirokatsu Takatsu, Tatsuro Koike, Hiroaki Kawakami, Reiko Ogasawara, Tadashi Shinkai
Publikováno v:
Journal of Nutritional Science and Vitaminology. 58:377-383
Several lines of evidence demonstrate the relationship between vitamin E deficiency and cognitive dysfunction in rodent models, but little is known about the underlying mechanisms. In this study, we found axonal injury in the hippocampal CA1 region o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c903faa179df5faf73b8a4ad3610969
https://doi.org/10.3177/jnsv.58.377
https://doi.org/10.3177/jnsv.58.377
Publikováno v:
Journal of Alzheimer's Disease. 24:759-766
To define whether hyperoxia induces the dysfunction of membrane fusion between synaptic vesicles with pre-synaptic plasma membranes in the nerve terminals, and whether vitamin E prevents this abnormal event, we investigated the influence of hyperoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99647a964b5d2218814425f09583e18d
https://doi.org/10.3233/jad-2011-101785
https://doi.org/10.3233/jad-2011-101785
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
The present study attempted to clarify whether over-secretion of glucocorticoids in the serum caused by increased hypothalamus-pituitary-adrenal activity induces oxidative stress in the rat brain, and how the stress causes the emergence of cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f595ca4cb8adac29ee2e5362546b62
http://europepmc.org/articles/PMC2966932
http://europepmc.org/articles/PMC2966932
Autor:
Tadashi Shinkai, Hirokatsu Takatsu, Kouichi Abe, Takeyuki Takahashi, Naoko Kobayashi, Shiro Urano, Taiji Machida
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
The present study was conducted in order to determine whether oxidative stress during aging involves dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis in association with the emergence of cognitive deficits. When young rats were subjected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7299e80f0d98a2b8b2d46c4dfd2cffc
http://europepmc.org/articles/PMC2735634
http://europepmc.org/articles/PMC2735634
Publikováno v:
Journal of Natural Medicines. 63:364-367
Lysichiton camtschatcense is a well-known plant in Japan where it has been used as a traditional medicine by the "Ainu" people for the treatment of acute nephritis. It is presumed that L. camtschatcense has an inhibitory effect against nephritis caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2277333312ca78b6e17abd00515c2a5
https://doi.org/10.1007/s11418-009-0333-9
https://doi.org/10.1007/s11418-009-0333-9
Publikováno v:
Journal of Nutritional Science and Vitaminology. 55:389-393
In order to verify whether vitamin E improves the cognitive impairment induced through aging, aged rats fed a vitamin E-supplemented diet had their learning and memory functions assessed in comparison with the aged rats fed a normal diet using a Morr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3862fdaad682c36ac711eba8a9bfca
https://doi.org/10.3177/jnsv.55.389
https://doi.org/10.3177/jnsv.55.389