Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hiroji Yoshikawa"'
Autor:
Fumio Fukui, Katsuya Gomi, Yoichiro Shiba, Nobufusa Serizawa, Hiroji Yoshikawa, Chiho Ono, Ichiro Watanabe
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 65:94-101
Phospholipase A1 (PLA1) is a hydrolytic enzyme that catalyzes the removal of the acyl group from position 1 of lecithin to form lysolecithin. The PLA1 gene, which had been cloned from Aspergillus oryzae, was expressed in Saccharomyces cerevisiae and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa926c71a9860edc8ae31f20f08c3555
https://doi.org/10.1271/bbb.65.94
https://doi.org/10.1271/bbb.65.94
Publikováno v:
Journal of Bioscience and Bioengineering. 89:426-430
In the course of studying carboxypeptidase Y (CPY) production, we found that the expression level of the gene, which is under the control of the GAL10 promoter, increased in a Saccharomyces cerevisiae gal80 mutant grown in a medium containing ethanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f0cc3d7cb7024e80aff4c5dce0a3cd
https://doi.org/10.1016/s1389-1723(00)89091-x
https://doi.org/10.1016/s1389-1723(00)89091-x
Autor:
Hiroji Yoshikawa, Yoshio Yao, Hidetsune Tamaoki, Fumio Fukui, Kawaguchi Junko, Hirokazu Ishikawa, Takeshi Ono
Publikováno v:
Journal of Bioscience and Bioengineering. 87:296-301
In order to develop a large-scale, high-yield production process for human calcitonin (hCT) in Escherichia coli , a stable expression plasmid was constructed and the expressed protein was modified for efficient cleavage by protease. Multiple copies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114af090799b2d6bb7bf86be3b85b03d
https://doi.org/10.1016/s1389-1723(99)80035-8
https://doi.org/10.1016/s1389-1723(99)80035-8
Autor:
Takao Okazaki, Ryuzo Enokita, Koichi Nonaka, Takahiro Yamamoto, Hiroji Yoshikawa, Fumio Maruyama
Publikováno v:
Actinomycetologica. 13:32-41
In the production culture of milbemycin α11 and α14 by Streptomyces hygroscopicus subsp. aureolacrimosus SANK 60393 (strain MA3-6126), two types of morphological mutants appeared in the late production phase, in which the milbemycin production rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ade2db9395625f8a9e20dd5d849d6d8d
https://doi.org/10.3209/saj.13_32
https://doi.org/10.3209/saj.13_32
Publikováno v:
Journal of Fermentation and Bioengineering. 86:545-549
Carboxypeptidase Y (CPY; EC 3. 4. 16. 1) encoded by the PRC1 gene is a yeast vacuolar protease. It enters the vacuole as a zymogen, proCPY, which is activated by vacuolar enzymes, proteinase A (PrA) and proteinase B (PrB). We previously showed that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::720cdb2fe75b789f62f7881f7fe2a2e6
https://doi.org/10.1016/s0922-338x(99)80004-x
https://doi.org/10.1016/s0922-338x(99)80004-x
Publikováno v:
Journal of Pesticide Science. 19:S125-S131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2834df559b695173c06a77a7cd01eb7f
https://doi.org/10.1584/jpestics.19.3_s125
https://doi.org/10.1584/jpestics.19.3_s125
Publikováno v:
Biotechnology and Bioengineering. 42:815-820
An automatic feeding process for microbial hydroxylation of ML236B sodium salt (ML-236B Na; compactin) by Streptomyces carbophilus SANK 62585 was developed. The hydroxylated product, pravastatin sodium salt (pravastatin; trade name Mevalotin), is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3bb49018af36aa4dd21387edf9c177
https://doi.org/10.1002/bit.260420705
https://doi.org/10.1002/bit.260420705
Publikováno v:
Journal of Fermentation and Bioengineering. 76:482-486
Fuzzy control was applied to the fermentation of ML-236B by Penicillium citrinum. In order to maintain the pH of the culture at a suitable level for ML-236B production (pH 3.7 to 3.9), a computer aided system using fuzzy control was designed for cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5ef334816015e2b0a3b2d29aa68e0e
https://doi.org/10.1016/0922-338x(93)90245-4
https://doi.org/10.1016/0922-338x(93)90245-4
Publikováno v:
Journal of Fermentation and Bioengineering. 76:476-481
In order to scale-up the production of ML-236B, a precursor of pravastatin sodium, by Penicillium citrinum H strain, a method for controlling mycelial morphology was developed to increase the number of free mycelia in the preculture process. The use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea2df1c67d9ba0e4bb64fbeab242554
https://doi.org/10.1016/0922-338x(93)90244-3
https://doi.org/10.1016/0922-338x(93)90244-3
Autor:
Hiroji Yoshikawa, Tetsuya Shioiri, Masatoshi Arai, Masahiko Hosobuchi, Jo Ohyama, Seigo Iwado
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 57:1414-1419
In order to increase the yield of ML-236B, an intermediate for pravastatin Na (an inhibitor of cholesterol synthesis) production, the improvements of an ML-236B producing strain of Penicillium citrinum, the medium composition, and the culture conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b261f7041458f4357405213665fb0b08
https://doi.org/10.1271/bbb.57.1414
https://doi.org/10.1271/bbb.57.1414