Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hirohumi Arakawa"'
Publikováno v:
Carcinogenesis. 33:1993-2000
Chromium (VI) [Cr(VI)], a ubiquitous environmental carcinogen, is generally believed to induce mainly mutagenic binary and ternary Cr(III)–deoxyguanosine (dG)-DNA adducts in human cells. However, both adenine (A) and guanine (G) mutations are found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e9fd56db586b8a1c0b3f8b1030af3b
https://doi.org/10.1093/carcin/bgs237
https://doi.org/10.1093/carcin/bgs237
Autor:
Hirohumi Arakawa, Moon-shong Tang
Publikováno v:
Chemical Research in Toxicology. 21:1284-1289
Hexavalent chromium [Cr(VI)] is an ubiquitous environmental contaminant and a well-known etiological agent of human lung cancer. Inside human cells, Cr(VI) is reduced to Cr(III), which can conjugate with amino acids, ascorbic acids, and glutathiones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1ba534a4c17cb774e495519af3a414
https://doi.org/10.1021/tx800046y
https://doi.org/10.1021/tx800046y
Publikováno v:
Carcinogenesis. 27:639-645
Hexavalent chromium [Cr(VI)] is a known etiological factor in human lung cancer. Cr(VI) exposure-related lung cancer has a high mutation incidence in the p53 gene. Upon intake in human cells Cr(VI) is reduced to Cr(III), which is able to conjugate wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2cf04f4f4010bf5f4f7ff3978de58d
https://doi.org/10.1093/carcin/bgi249
https://doi.org/10.1093/carcin/bgi249
Publikováno v:
DNA and Cell Biology. 24:394-401
The involvement of the Fe cations in autoxidation in cells and tissues is well documented. DNA is a major target in such reaction, and can chelate Fe cation in many ways. The present study was designed to examine the interaction of calf-thymus DNA wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e99c7cd6da1b1cf27ebfc0402edde8c
https://doi.org/10.1089/dna.2005.24.394
https://doi.org/10.1089/dna.2005.24.394
Publikováno v:
Biophysical Journal. 84:2460-2466
Although structural differences for the Mg-DNA and Ca-DNA complexes are provided in the solid state, such comparative study in aqueous solution has been less investigated. The aim of this study was to examine the bindings of Mg and Ca cations with ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d69c146a661ae1e95cb02c4a47dfe38
https://doi.org/10.1016/s0006-3495(03)75050-4
https://doi.org/10.1016/s0006-3495(03)75050-4
Publikováno v:
Journal of Japan Society on Water Environment. 26:203-207
Analysis of hull and wood vinegars was performed using infrared spectroscopy [IR], Sephadex G-25 and G-10 columns and paper chromatography to elucidate the components that were implicated in Cr (VI) reductive activity. The IR study suggests the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473118d2864f8ab818441e82a3314fab
https://doi.org/10.2965/jswe.26.203
https://doi.org/10.2965/jswe.26.203
Publikováno v:
Bulletin of the Chemical Society of Japan. 74:1075-1082
Cr(VI) salts are well known to be carcinogen, and are reduced by various cellular components to form cross-linked Cr(III) products. Organic compounds, such as gallic acid (GA) and ethyl gallate (EGA), reduce Cr(VI) to Cr(III) to form Cr(III)-gallate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8ce3fa83221408a656f51d562c0f0bf
https://doi.org/10.1246/bcsj.74.1075
https://doi.org/10.1246/bcsj.74.1075
Publikováno v:
Journal of Biological Chemistry. 275:10150-10153
Chromium(VI) salts are well known to be mutagens and carcinogens and to easily cross the cell membranes. Because they are powerful oxidizing agents, Cr(VI) reacts with intracellular materials to reduce to trivalent form, which binds DNA. This study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::290cd87a13c31c7dcbda9338dad20e0e
https://doi.org/10.1074/jbc.275.14.10150
https://doi.org/10.1074/jbc.275.14.10150
Autor:
Hirohumi Arakawa, Norimoto Watanabe
Publikováno v:
Bulletin of the Chemical Society of Japan. 69:1133-1137
Reaction mixtures containing constant amounts of water-extract from withered oak leaves and various concentrations of potassium chromate were incubated, and each reaction mixture was fractionated by a Sephadex G-25 column. The concentrations of the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35622deddd58cd9e5a889927ab04e4c0
https://doi.org/10.1246/bcsj.69.1133
https://doi.org/10.1246/bcsj.69.1133
Publikováno v:
Chemistry Letters. 22:2113-2116
Introduction of water-extracts from withered oak leaves into potassium chromate readily diminished Cr(VI) to give water soluble chromium species which are presumably composed of tannin and Cr(III). Thus, this method is useful for treatment of potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d49e24ebe97e8ce78a7133e70eabf2b
https://doi.org/10.1246/cl.1993.2113
https://doi.org/10.1246/cl.1993.2113