Výsledky vyhledávání - "Hirohisa Nakao"

Decreased nitric oxide-mediated natural killer cell activation in chronic fatigue syndrome

Autor: Yoko Horikawa, Yuji Matsuzawa, Jun Ishikawa, Yoshio Kanayama, Megumu Ogawa, Tetsuo Nishiura, Masafumi Yoshimura, Hirohisa Nakao, Yoshiaki Tomiyama, Itaru Matsumura, Yu Okajima, Hitoshi Yoshida, Yuzuru Kanakura

Publikováno v: European Journal of Clinical Investigation. 28:937-943

Background L-Arginine ( L-Arg), one of the essential amino acids, has been reported to have an immunomodulatory effect. The precise mechanism of the L-Arg-induced natural killer (NK) cell activation remains unresolved ,and the effect of L-Arg on NK c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::375e67bae1bf1cff1ac4f63e2f1d2b11
https://doi.org/10.1046/j.1365-2362.1998.00373.x

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Functional role of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor in cell adhesion and proliferation of a human myeloma cell line OPM-2

Autor: Yu Okajima, Megumu Ogawa, Yoshio Kanayama, Yuji Matsuzawa, Tetsuo Nishiura, Yuzuru Kanakura, Takahiro Karasuno, Hitoshi Yoshida, Yoko Horikawa, Masafumi Yoshimura, Hirohisa Nakao

Publikováno v: Blood. 88:3546-3554

The molecular mechanism underlying the interaction between myeloma cells and stromal cells was investigated by using a human myeloma cell line (OPM-2) and human umbilical vein endothelial cells (HUVECs). Adhesion of OPM-2 cells to HUVECs was found to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527afd4900c34fb665c80b941aac7676
https://doi.org/10.1182/blood.v88.9.3546.bloodjournal8893546

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Glycosidase inhibitors (castanospermine and swainsonine) and neuraminidase inhibit pokeweed mitogen-induced B cell maturation

Autor: Yoshio Kanayama, Seiichiro Tarui, Takahiro Karasuno, Hirohisa Nakao, Takeshi Yonezawa, Tetsuo Nishiura

Publikováno v: European Journal of Immunology. 22:2003-2008

Castanospermine (CSP), an inhibitor of alpha-glucosidase, enhanced immunoglobulin (Ig) release in a Staphylococcus aureus Cowan I (SAC)-induced lymphocyte culture (Scand. J. Immunol. 1990. 32: 529). In a pokeweed mitogen (PWM)-human lymphocyte cultur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1790433c0751ad3a5b8426773fffb0
https://doi.org/10.1002/eji.1830220808

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Hypogalactosylation of immunoglobulin G sugar chains and elevated serum interleukin 6 in Castleman's disease

Autor: Yoshio Kanayama, Seiichiro Tarui, Atsushi Nishikawa, Naoyuki Taniguchi, Hirohisa Nakao, Tetsuo Nishiura

Publikováno v: Clinica Chimica Acta. 197:221-228

Immunoglobulin G (IgG) molecule has two N-linked complex type oligosaccharides, consisting of a mixture of at least 12 different structures. The pattern of these oligosaccharides is fairly constant in healthy individuals. In three patients with Castl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685948e748b9d89b7a047fdd7c740751
https://doi.org/10.1016/0009-8981(91)90142-y

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Secretory component, the receptor for polymeric immunoglobulin, has nothing to do with beta-galactosyltransferase in human milk

Autor: Naoyuki Taniguchi, Hirohisa Nakao, Hisashi Narimatsu, Naoki Mafune, Kunihiko Kobayashi

Publikováno v: Immunology letters. 50(1-2)

Secretory component (SC) in external secretions is a soluble form of the polymeric immunoglobulin-receptor that is expressed on the cell membrane of mucosal epithelial cells. beta-(1-4)galactosyl transferase (beta-GT) is an enzyme that transfers gala

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e025782a15fa36efc1cda10a13d9a1f4
https://pubmed.ncbi.nlm.nih.gov/8793566

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High expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis

Autor: Yoshio Kanayama, Yoshito Ihara, Masafumi Yoshimura, Tetsuo Nishiura, Atsushi Nishikawa, Hirohisa Nakao, Yuji Matuzawa, Naoyuki Taniguchi

Publikováno v: International journal of cancer. 60(4)

The activity and mRNA expression of UDP-N-acetylglucosamine: beta-D mannoside beta-1,4-N-acetylglucosaminyl transferase III (GnT-III: EC 2.4.1.144) were investigated in hematological malignancies. GnT-III activity was elevated in patients with chroni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f7930673d654a365904e8b86768033
https://pubmed.ncbi.nlm.nih.gov/7829256

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A Lack of Relationship Between Secretory Component and Galactosyltransferase in Human Milk

Autor: Kunihiko Kobayashi, Naoyuki Taniguchi, Naoki Mafune, Hisashi Narimatsu, Hirohisa Nakao

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781461357964

Secretory component (SC), a glycoprotein produced by mucosal epithelial cells and expressed on their cell surface, is known to be the receptor of polymeric immunoglobulins (Ig) of IgA and IgM. SC on the basolateral surface of epithelial cells binds p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6e0628a93c2f709c86eb9c16bb401e6
https://doi.org/10.1007/978-1-4615-1941-6_134

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Cyclic thrombocytopenia associated with IgM anti-GPIIb-IIIa autoantibodies

Autor: Yoshiyuki Kurata, Yoshio Kanayama, Satoru Kosugi, Yuji Matsuzawa, Hirokazu Kashiwagi, Yoshiaki Tomiyama, Hirohisa Nakao, Masamichi Shiraga

Publikováno v: British journal of haematology. 88(4)

We studied a female patient with cyclic fluctuation in platelet count following splenectomy for autoimmune thrombocytopenia. The cyclical fluctuation appeared to be in phase with her menstrual cycle and her platelet count was low during menses. Bone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869fe79c7f063a0d368b7444dcbd0513
https://pubmed.ncbi.nlm.nih.gov/7529542

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T cell abnormalities in mixed connective tissue disease complicated with Klinefelter's syndrome

Autor: Hirohisa Nakao, Yuji Matsuzawa, Yoshio Kanayama, Katsuhiko Ishihara, Masafumi Yoshimura, Yuzuru Kanakura

Publikováno v: Internal medicine (Tokyo, Japan). 33(11)

We report a 28-year-old Japanese with Klinefelter's syndrome who developed mixed connective tissue disease (MCTD) and Sjogren syndrome. Previously being well, he presented with Raynaud's phenomenon, dry eye, fever and polyarthralgia. Clinical examina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cde30152f9926daabc5c4210189fa47
https://pubmed.ncbi.nlm.nih.gov/7849389

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Modulation of N-acetylglucosaminyltransferase III, IV and V activities and alteration of the surface oligosaccharide structure of a myeloma cell line by interleukin 6

Autor: Takeshi Yonezawa, Tetsuo Nishiura, Yoshio Kanayama, Seiichiro Tarui, Masato Iida, Atsushi Nishikawa, Naoyuki Taniguchi, Takahiro Karasuno, Hirohisa Nakao

Publikováno v: Biochemical and biophysical research communications. 172(3)

The activity of N-acetylglucosaminyltransferase (GnT) III, IV and V on a myeloma cell line, OPM-1, was examined after incubation with interleukin 6 (IL-6). While augmenting cell proliferation, IL-6 resulted in a decrease of GnT III activity and an in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039722f86bbc78c296ecd9ad145be3a5
https://pubmed.ncbi.nlm.nih.gov/2147103

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