Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Hirohide Takahashi"'
Publikováno v:
eLife, Vol 12 (2023)
Volume-regulated anion channels (VRACs) mediate volume regulatory Cl- and organic solute efflux from vertebrate cells. VRACs are heteromeric assemblies of LRRC8A-E proteins with unknown stoichiometries. Homomeric LRRC8A and LRRC8D channels have a sma
Externí odkaz:
https://doaj.org/article/aa7ea42837e04d9ba238be46ae7f3f71
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
IP3 receptors are intracellular calcium channels involved in numerous signaling pathways. Here, the authors present the cryo-EM structures of type-3 IP3 receptors in multiple gating conformations, including the active state revealing the molecular me
Externí odkaz:
https://doaj.org/article/9b72378f9eee4865be21cd1200687d40
Autor:
Daniel Duzdevich, Jinliang Li, Jhoon Whang, Hirohide Takahashi, Kunio Takeyasu, David T F Dryden, A Jennifer Morton, J Michael Edwardson
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17119 (2011)
In the R6/2 mouse model of Huntington's disease (HD), expansion of the CAG trinucleotide repeat length beyond about 300 repeats induces a novel phenotype associated with a reduction in transcription of the transgene.We analysed the structure of polym
Externí odkaz:
https://doaj.org/article/43602c689ea040d68d70e262bd25071c
Volume-regulated anion channels (VRACs) mediate Cl- and organic solute efflux from vertebrate cells and are essential for cell volume homeostasis. VRACs are heteromeric assemblies of LRRC8A-E proteins with unknown stoichiometries. Homomeric LRRC8A an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23a05936febe469ed7b6913d6aeb7e0f
https://doi.org/10.1101/2022.07.28.501913
https://doi.org/10.1101/2022.07.28.501913
Publikováno v:
Biophysical Journal. 122:112a
Publikováno v:
Biophysical Journal. 122:113a
Calcium (Ca2+) is a universal and versatile cellular messenger used to regulate numerous cellular processes in response to external or internal stimuli. A pivotal component of the Ca2+ signaling toolbox in cells is the inositol 1,4,5-triphosphate (IP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e50309500de0ac90b19ed4bd763e74cd
https://doi.org/10.1101/2021.10.18.464806
https://doi.org/10.1101/2021.10.18.464806
Publikováno v:
Nature communications. 13(1)
A pivotal component of the calcium (Ca
Publikováno v:
Biophysical Journal. 121:174a-175a