Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Hirohei Yamamura"'
Autor:
Eisuke Enoki, Kiyonao Sada, Xiujuan Qu, Shinkou Kyo, S.M. Shahjahan Miah, Tomoko Hatani, Akio Tomoda, Hirohei Yamamura
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 3, Pp 329-333 (2004)
Antigen-induced aggregation of the high affinity IgE receptor (FcεRI) on mast cells induces degranulation to release chemical mediators, leading to acute allergic inflammation. We have demonstrated that the treatment of rat mast cells, RBL-2H3, with
Externí odkaz:
https://doaj.org/article/0366e304e019405987f2ff910deb4da8
Autor:
Hirohei Yamamura, Shun-ichi Nakamura
Publikováno v:
Journal of Biochemistry. 148:125-130
It is 6 years since we received the tragic news that our great mentor Dr Yasutomi Nishizuka passed away suddenly at the age of 72 years. Dr Nishizuka made several epoch-making discoveries in his life, e.g. the tryptophan metabolism, protein synthesis
Autor:
Chisato Tanaka, Xiujuan Qu, Shusuke Takahashi, Hirohei Yamamura, Ryoichi Hazama, Kunio Yokoyama, Jinsong He, Emi Kinoshita, Yumi Tohyama, Kaoru Tohyama
Publikováno v:
Genes to Cells. 14:871-884
Osteoclasts are bone-resorbing cells which play an exclusive role in bone remodeling, but the molecular mechanisms of osteolysis, how osteoclasts are activated and how the lytic granules are finally released towards the bone matrix are poorly underst
Autor:
Yumi Tohyama, Hirohei Yamamura
Publikováno v:
Journal of Biochemistry. 145:267-273
Spleen tyrosine kinase (Syk) is a non-receptor protein tyrosine kinase expressed in a wide range of haematopoietic cells. At the initial stage of investigation, main exploring was toward its functions in platelets and in classical immunoreceptor sign
Autor:
Tomoko Takano, Yumi Tohyama, Chisato Tanaka, Hirohei Yamamura, Kaoru Tohyama, Chiseko Noda, Jinsong He, Toshinori Kondo
Publikováno v:
Biochemical and Biophysical Research Communications. 362:951-957
(-)-Epigallocatechin-3-gallate (EGCG), a major constituent of green tea polyphenols, has been shown to suppress cancer cell proliferation and induce apoptosis. In this study we investigated its efficacy and the mechanism underlying its effect using h
Autor:
Hirohei Yamamura, Yumi Tohyama
Publikováno v:
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life). 58:304-308
Phagocytosis is a central event in the innate immune responses that are triggered by the association between ligands on the surface of pathogens and receptors on the membrane of phagocytes. Particularly, complement-mediated phagocytosis is accomplish
Autor:
Hirohei Yamamura, Emi Kinoshita, Rina Kurihara, Yumi Tohyama, Hiromu Naruse, Takayuki Tsujioka, Yoshinao Katsumata, Satoshi Matsusaka
Publikováno v:
Journal of Biological Chemistry. 281:12908-12918
The possible role of the peripheral cannabinoid receptor (CB2) in neutrophil migration was investigated by using human promyelocytic HL60 cells differentiated into neutrophil-like cells and human neutrophils isolated from whole blood. Cell surface ex
Autor:
Shun-ichi Nakamura, Hirohei Yamamura
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 52:219-230
Yasutomi Nizhizuka was born in Seido Village, Muko–gun (now City of Ashiya), Hyogo–Prefecture, on 12 July 1932, as the second son of Yasunobu and Nobuko Nishizuka. His elder brother, Yasuaki (1922–95, pathologist, President of Aichi Cancer Cent
Autor:
Qingyu Qin, Ryoko Inatome, Junichi Yuasa-Kawada, Hirohei Yamamura, Shigeru Yanagi, Azusa Hotta
Publikováno v:
Molecular Biology of the Cell. 16:32-39
Collapsin response mediator proteins (CRMPs) have been implicated in signaling of axonal guidance, including semaphorins. We have previously identified a unique member of this gene family, CRMP-associated molecule CRAM (CRMP-5), which is phylogenetic
Autor:
Jinsong He, Yumi Tohyama, Masahiko Kobayashi, Kaoru Tohyama, Tomoko Takano, Yuhong Shi, Ken Ichi Yamamoto, Hirohei Yamamura, Chiseko Noda
Publikováno v:
Genes to Cells. 10:23-35
To investigate the mechanism of B cell receptor (BCR)-mediated apoptosis, we utilized immature B cell lines, DT40 and WEHI-231. In both cell lines, BCR-crosslinking caused the increase in lysosomal pH with early apoptotic changes characterized by chr