Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hiroharu Mifune"'
Autor:
Ichiro Tokubuchi, Yuji Tajiri, Shimpei Iwata, Kento Hara, Nobuhiko Wada, Toshihiko Hashinaga, Hitomi Nakayama, Hiroharu Mifune, Kentaro Yamada
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171293 (2017)
Metformin is known to have a beneficial effect on body weight and body composition, although the precise mechanism has not been elucidated yet. The aim of this study is to investigate the effects of metformin on energy metabolism and anthropometric f
Externí odkaz:
https://doaj.org/article/3273a7c6c70248fbba0b8b3097e5156a
Autor:
Yuji Tajiri, Masayasu Kojima, Hiroharu Mifune, Yukie Kawahara, Yoshihiro Nishi, Takahiro Sato, Tatsuyuki Kakuma, Akinori Nishi, Kento Hara, Yusuke Sakai, Ryouichi Mitsuzono
Publikováno v:
The Journal of Endocrinology
We previously reported that voluntary exercise contributed to the amelioration of abnormal feeding behavior with a concomitant restoration of ghrelin production in a rat model of obesity, suggesting a possible relationship between exercise and appeti
Autor:
Shimpei Iwata, Yuji Tajiri, Ichiro Tokubuchi, Masayasu Kojima, Ryouichi Mitsuzono, Kento Hara, Yoshihiro Nishi, Hiroharu Mifune, Kentaro Yamada
Publikováno v:
Peptides. 71:49-55
In the present study, effects of voluntary exercise in an obese animal model were investigated in relation to the rhythm of daily activity and ghrelin production. Male Sprague-Dawley rats were fed either a high fat diet (HFD) or a chow diet (CD) from
Autor:
Sachiyo Takushima, Rumiko Hirata, Daizo Hori, Hiroharu Mifune, Eiichiro Tanaka, Toshiharu Kamura, Ryosuke Doi, Akiko Nonoshita, Yoshihiro Nishi, Kimio Ushijima
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 41:540-550
Aim Diminished vasodilator activity during pregnancy, which augments vascular responses to vasoconstrictors, is one reason for the onset of pre-eclampsia and superimposed pre-eclampsia. It is known that Dahl salt-sensitive (Dahl-S) rats develop salt-
Autor:
Hiroharu Mifune, Yuji Tajiri, Yusuke Sakai, Yukie Kawahara, Kento Hara, Takahiro Sato, Yoshihiro Nishi, Akinori Nishi, Ryouichi Mitsuzono, Tatsuyuki Kakuma, Masayasu Kojima
Publikováno v:
Journal of Endocrinology; Jan2020, Vol. 244 Issue 1, p123-132, 10p
Autor:
Masayoshi Kage, Suguru Yasuoka, Hidemi Kajimoto, Hiroshi Kudo, Mitsuhisa Koga, Hisashi Kai, Tsutomu Imaizumi, Takanobu Miyamoto, Yoshitaka Hirooka, Takahiro Anegawa, Hiroharu Mifune, Narimasa Takayama
Publikováno v:
Circulation Journal. 77:1474-1481
Background: Hypertensive patients with large blood pressure variability (BPV) have aggravated target organ damage. Because the aldosterone/mineralocorticoid receptor (MR) system is a possible mechanism of hypertensive organ damage, we investigated in
Autor:
Taku Masuyama, Yoshihiro Nishi, Masayasu Kojima, Kenji Kangawa, Hiroshi Hosoda, Hiroharu Mifune, Yuji Tajiri
Publikováno v:
Metabolism. 61:491-495
An abnormal eating behavior is often associated with diabetes mellitus in individuals. In the present study, we investigated the mechanisms underlying the relationship among uncontrolled diabetes, food intake, and the production of ghrelin, an orexig
Publikováno v:
Experimental Animals. 61:131-138
A-type (atrial) natriuretic peptide (ANP) levels in the heart and plasma were examined by immunohistochemistry, electron microscopy, and radioimmunoassay (RIA) in angiotensin II type 1a receptor knockout (Agtr1a KO) mice. Additionally, the ANP mRNA l
Autor:
Junichi Honda, Shinzo Takamori, Kazuo Shirouzu, Norman Y. Kimura, Toshihiro Matsuo, Kanetaka Maeshiro, Hiroharu Mifune
Publikováno v:
Surgery Today. 38:130-134
Elevated plasma A-type natriuretic peptide (ANP) levels in sepsis cause fluid transfer into extravascular spaces. We investigated the changes in ANP concentrations and natriuretic peptide receptor (NPR) expression induced by thiorphan, a neutral endo
Autor:
Kento Hara, Shimpei Iwata, Nobuhiko Wada, Hiroharu Mifune, Toshihiko Hashinaga, Yuji Tajiri, Hitomi Nakayama, Ichiro Tokubuchi, Kentaro Yamada
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0171293 (2017)
PLoS ONE, Vol 12, Iss 2, p e0171293 (2017)
Objective Metformin is known to have a beneficial effect on body weight and body composition, although the precise mechanism has not been elucidated yet. The aim of this study is to investigate the effects of metformin on energy metabolism and anthro