Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Hiroh Ikezawa"'
Publikováno v:
Archives of Biochemistry and Biophysics. 436:227-236
Sphingomyelinase (SMase) from Bacillus cereus has been known to be activated by Mg 2+ , Mn 2+ , and Co 2+ , but strongly inhibited by Zn 2+ . In the present study, we investigated the effects of several kinds of metal ions on the catalytic activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f2435ec6f6700d5474a4b074579f35
https://doi.org/10.1016/j.abb.2005.02.019
https://doi.org/10.1016/j.abb.2005.02.019
Autor:
Hiroh Ikezawa
Publikováno v:
Journal of Toxicology: Toxin Reviews. 23:479-508
Bacterial phosphatidylinositol‐specific phospholipases C have been shown not only to cause breakdown of phosphatidylinositol but also to release GPI‐anchored proteins from the plasma membranes of eucaryotes. Several enzymes in this group have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461e86b0d221212590e7c4c1e8cd803d
https://doi.org/10.1081/txr-200038412
https://doi.org/10.1081/txr-200038412
Publikováno v:
Journal of Biochemistry. 133:279-286
Bacillus cereus sphingomyelinase (SMase) is an extracellular hemolysin classified into a group of Mg(2+)-dependent neutral SMases (nSMase). Sequence comparison of bacterial and eukaryotic Mg(2+)-dependent nSMases has shown that several amino acid res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d820e0f605707dd2c5d9b47252de630b
https://doi.org/10.1093/jb/mvg038
https://doi.org/10.1093/jb/mvg038
Autor:
Masayoshi Imagawa, Hiroh Ikezawa, Kikuo Tsukamoto, Shinobu Fujii, Kiyoshi Ikeda, Takashi Obama
Publikováno v:
Biological and Pharmaceutical Bulletin. 26:920-926
Bacillus cereus sphingomyelinase belongs to the Mg(2+)-dependent neutral sphingomyelinase, which hydrolyses sphingomyelin to phosphocholine and ceramide, and acts as an extracellular hemolysin. The triplet residues, His151-Asp195-His296, of the enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2c6ab26696b066b5b994ef424e9e60
https://doi.org/10.1248/bpb.26.920
https://doi.org/10.1248/bpb.26.920
Autor:
Hiroh Ikezawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:409-417
From the numerous studies developed at the last quarter of the 20th century, glycosylphosphatidylinositol (GPI) anchor has been established as a unique mode of protein binding to the plasma membrane. The core structure of this anchor consists of etha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf3f5e1fd59009b0009cbad573a5153
https://doi.org/10.1248/bpb.25.409
https://doi.org/10.1248/bpb.25.409
Autor:
Hiroe Honda, Yasukazu Oomoto, Takemasa Takii, Hiroh Ikezawa, Kikuo Onozaki, Tomoko Kobayashi, Shigezo Udaka, Satoshi Sasayama
Publikováno v:
Journal of Interferon & Cytokine Research. 19:1325-1331
Interleukin-1 receptor antagonist (IL-1RA) has been used as a tool to study the biologic activity of IL-1 and as a possible therapeutic substance for inflammatory disease. To perform in vivo study, however, large quantities of IL-1RA are required. Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59352b413217ab0d21a68140a9bcaee2
https://doi.org/10.1089/107999099313000
https://doi.org/10.1089/107999099313000
Autor:
Tetsuyuki Kobayashi, Hiroh Ikezawa, Rieko Tanaka-Ishii, Ryo Taguchi, Kimiko Murakami-Murofushi
Publikováno v:
Life Sciences. 65:2185-2191
A novel bioactive lipid, cyclic phosphatidic acid (cPA), was identified in lipids bound to human serum albumin. A cPA fraction was extracted and purified from human serum albumin by use of a combination of preparative TLC and HPLC. Electrospray ioniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48118a6857ffab7d2e08c3d32a34d1c0
https://doi.org/10.1016/s0024-3205(99)00483-x
https://doi.org/10.1016/s0024-3205(99)00483-x
Autor:
Hideo Nakano, Hiroh Ikezawa, Yugo Iwasaki, Tomoko Kobayashi, Tsuneo Yamane, Akiko Ichihashi, Yukiko Tsubouchi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1391:52-66
Two phosphatidylinositol-specific phospholipase C (PI-PLC) genes from Streptomyces antibioticus were cloned by a shotgun method using Streptomyces lividans TK24 as a host. The genes of the two PI-PLCs (named as PLC1 and PLC2) were adjoined and opposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d23e5c92587c3328aa667212ae00fe5
https://doi.org/10.1016/s0005-2760(97)00191-4
https://doi.org/10.1016/s0005-2760(97)00191-4
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1328:185-196
Bovine liver 5′-nucleotidase is a GPI-anchored protein whose Ser523 attaches to GPI as the ω-site. For GPI-modification, pro-protein of the enzyme possesses a signal peptide at the C-terminus, comprising a hydrophilic spacer sequence of 8 amino ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99ca67b910aa0a38f0c04d39ab439e2
https://doi.org/10.1016/s0005-2736(97)00084-9
https://doi.org/10.1016/s0005-2736(97)00084-9
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1334:1-4
GPI-anchored proteins are distributed ubiquitously in eukaryotes, but not in procaryotes. By methabolic-labeling of Sulfolobus acidocaldarius cells, 14C-radiolabeled precursors of GPI and caldarchaetidylinositol were incorporated into 120, 143 and 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240ee2f23489b7d1a8df074449c9dc8c
https://doi.org/10.1016/s0304-4165(96)00099-2
https://doi.org/10.1016/s0304-4165(96)00099-2