Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hirofumi Watari"'
Autor:
Ting Fu, Isabelle Arnoux, Jan Döring, Hendrik Backhaus, Hirofumi Watari, Ignas Stasevicius, Wei Fan, Albrecht Stroh
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102184- (2021)
Summary: Two-photon (2-P) all-optical approaches combine in vivo 2-P calcium imaging and 2-P optogenetic modulations. Here, firstly, we combined in vivo juxtacellular recordings and GCaMP6f-based 2-P calcium imaging in mouse visual cortex to tune our
Externí odkaz:
https://doaj.org/article/ad64b70bead74d6e97e03c046627dc9f
Autor:
Isabelle Arnoux, Michael Willam, Nadine Griesche, Jennifer Krummeich, Hirofumi Watari, Nina Offermann, Stephanie Weber, Partha Narayan Dey, Changwei Chen, Olivia Monteiro, Sven Buettner, Katharina Meyer, Daniele Bano, Konstantin Radyushkin, Rosamund Langston, Jeremy J Lambert, Erich Wanker, Axel Methner, Sybille Krauss, Susann Schweiger, Albrecht Stroh
Publikováno v:
eLife, Vol 7 (2018)
Catching primal functional changes in early, ‘very far from disease onset’ (VFDO) stages of Huntington’s disease is likely to be the key to a successful therapy. Focusing on VFDO stages, we assessed neuronal microcircuits in premanifest Hdh150
Externí odkaz:
https://doaj.org/article/031434054df44d4c9f2caf98fe3f48e2
Autor:
Miriam Schwalm, Dennis R. Tabuena, Curtis Easton, Thomas J. Richner, Pierre Mourad, Hirofumi Watari, William J. Moody, Albrecht Stroh
Publikováno v:
Journal of neurophysiology, 128(4):763-777
The spatiotemporal representation of neural activity during rest and upon sensory stimulation in cortical areas is highly dynamic and may be predominantly governed by cortical state. On the mesoscale level, intrinsic neuronal activity ranges from a p
Autor:
Albrecht Stroh, Wei Fan, Jan Döring, Isabelle Arnoux, Ignas Stasevičius, Hirofumi Watari, Ting Fu, Hendrik Backhaus
Publikováno v:
iScience, 24(3):102184
iScience
iScience, Vol 24, Iss 3, Pp 102184-(2021)
Iscience, Cambridge : Elsevier, 2021, vol. 24, iss. 3, art. no. 102184, p. [1-31]
iScience
iScience, Vol 24, Iss 3, Pp 102184-(2021)
Iscience, Cambridge : Elsevier, 2021, vol. 24, iss. 3, art. no. 102184, p. [1-31]
Summary Two-photon (2-P) all-optical approaches combine in vivo 2-P calcium imaging and 2-P optogenetic modulations. Here, firstly, we combined in vivo juxtacellular recordings and GCaMP6f-based 2-P calcium imaging in mouse visual cortex to tune our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d1f168be33c338340952b52ec4340c
https://www.sciencedirect.com/science/article/pii/S2589004221001528#appsec2
https://www.sciencedirect.com/science/article/pii/S2589004221001528#appsec2
Two-photon (2-P) all-optical approaches combine in vivo 2-P calcium imaging and 2-P optogenetic modulations and have the potential to build a framework for network-based therapies, e.g. for rebalancing maladaptive activity patterns in preclinical mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d809db2a93094bbbb7d3fac4703348c8
https://doi.org/10.1101/2020.04.20.049726
https://doi.org/10.1101/2020.04.20.049726
Autor:
Hirofumi Watari, Sybille Krauss, Katharina Meyer, Sven Buettner, Isabelle Arnoux, Axel Methner, Rosamund F. Langston, Nina Offermann, Daniele Bano, Konstantin Radyushkin, Jennifer Krummeich, Partha Narayan Dey, Erich E. Wanker, Jeremy J. Lambert, Stephanie Weber, Susann Schweiger, Olivia Monteiro, Nadine Griesche, Changwei Chen, Albrecht Stroh, Michael Willam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d264c210d5b7c6d3b9fe835ae7698487
https://doi.org/10.7554/elife.38744.032
https://doi.org/10.7554/elife.38744.032
Autor:
Jennifer Krummeich, Jeremy J. Lambert, Axel Methner, Sven Buettner, Isabelle Arnoux, Hirofumi Watari, Nina Offermann, Daniele Bano, Sybille Krauss, Michael Willam, Albrecht Stroh, Konstantin Radyushkin, Erich E. Wanker, Susann Schweiger, Olivia Monteiro, Stephanie Weber, Rosamund F. Langston, Partha Narayan Dey, Nadine Griesche, Changwei Chen, Katharina Meyer
Publikováno v:
eLife 7, e38744 (2018). doi:10.7554/eLife.38744
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Catching primal functional changes in early, ‘very far from disease onset’ (VFDO) stages of Huntington’s disease is likely to be the key to a successful therapy. Focusing on VFDO stages, we assessed neuronal microcircuits in premanifest Hdh150
Publikováno v:
The Journal of Physiology. 592:711-727
Most cells maintain [Ca(2+)]i at extremely low levels; calcium entry usually occurs briefly, and within seconds it is cleared. However, at embryonic day 12.5 in the mouse brainstem, trains of spontaneous events occur with [Ca(2+)]i staying close to p
Publikováno v:
The Journal of Physiology. 591:973-983
Key points • A wave of electrical activity occurs in the developing brain for a certain period of time before sensory, motor and cognitive functions mature. • This electrical activity, or spontaneous activity, originates, spreads, then later retr
Autor:
Hirofumi Watari, Nathan J. Lautermilch, Xin Jiang, William A. Catterall, Todd Scheuer, Ruth E. Westenbroek
Publikováno v:
Proceedings of the National Academy of Sciences. 105:341-346
Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) is a key regulator of synaptic responses in the postsynaptic density, but understanding of its mechanisms of action in the presynaptic neuron is incomplete. Here we show that CaMKII constitutivel