Zobrazeno 1 - 10
of 575
pro vyhledávání: '"Hirofumi Watanabe"'
Autor:
Ruolan Song, Hirofumi Watanabe, Kelsey Tjen, Baylee C. Westbury, Takako Makita, Ge Tao, Henry M. Sucov
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Mammalian cardiomyocytes (CMs) mostly become polyploid shortly after birth. Because this feature may relate to several aspects of heart biology, including regeneration after injury, the mechanisms that cause polyploidy are of interest. BALB/
Externí odkaz:
https://doaj.org/article/9132e3360304417d9d6320ad19f42e46
Autor:
Yoshihiro Kitahara, Toshihiro Shirai, Keita Hirai, Taisuke Akamatsu, Hirofumi Watanabe, Hiromasa Nakayasu
Publikováno v:
Allergology International, Vol 72, Iss 1, Pp 169-172 (2023)
Externí odkaz:
https://doaj.org/article/681c999a138b4c9193fd4c8edf14f5f3
Autor:
Hirofumi Watanabe, Sho Mokuda, Tadahiro Tokunaga, Hiroki Kohno, Michinori Ishitoku, Kei Araki, Tomohiro Sugimoto, Yusuke Yoshida, Toshihiro Yamamoto, Mayuko Matsumoto, Junya Masumoto, Shintaro Hirata, Eiji Sugiyama
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-15 (2023)
Abstract Background Blood coagulation factor XIII (FXIII) promotes cross-linking between fibrin molecules at the final stage of the blood coagulation cascade. However, its expression in cells or tissues and function, particularly factor XIII subunit
Externí odkaz:
https://doaj.org/article/66ed8a674d6348bbaa2507035089de7a
Autor:
Hirofumi Watanabe, Fumiyoshi Fujishima, Toru Motoi, Yayoi Aoyama, Tetsuya Niihori, Masanobu Takahashi, Sho Umegaki, Hisashi Oishi, Hiroshi Tada, Ryo Ichinohasama, Hironobu Sasano
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-6 (2022)
Abstract Background Germline TP53 mutations have been frequently reported in patients with Li–Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies. Mutations other than germline TP53 mutations can also cause LFS-associated
Externí odkaz:
https://doaj.org/article/f5fd271aa8af47869ff2081aab790de4
Autor:
Hirofumi Watanabe, Shin Goto, Michihiro Hosojima, Hideyuki Kabasawa, Naofumi Imai, Yumi Ito, Ichiei Narita
Publikováno v:
Human Genome Variation, Vol 10, Iss 1, Pp 1-3 (2023)
Abstract We present a family of two female Alport syndrome patients with a family history of impaired glucose tolerance. Whole exome sequencing identified a novel heterozygous variant of COL4A5 NM_033380.3: c.2636 C > A (p.S879*) and a rare variant o
Externí odkaz:
https://doaj.org/article/c3a5b6b3fd0143cabf5a829288d4b5c0
Autor:
Chihiro Inoue, Sachiko Konosu-Fukaya, Kazuhiro Murakami, Ryoko Saito-Koyama, Hirofumi Watanabe, Hideki Mitomo, Naoya Ishibashi, Takafumi Sugawara, Toshiharu Tabata, Hironobu Sasano, Yasuhiro Nakamura
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Pulmonary carcinoid tumors rarely coexist with non-small cell lung carcinoma, and only nine cases have been reported previously. The pathogenesis and origin of these combined tumors remain unclear because of its rarity. Case prese
Externí odkaz:
https://doaj.org/article/0c424fec637a4268ae873fdc81d38663
Autor:
Michinori Ishitoku, Sho Mokuda, Kei Araki, Hirofumi Watanabe, Hiroki Kohno, Tomohiro Sugimoto, Yusuke Yoshida, Takemasa Sakaguchi, Junya Masumoto, Shintaro Hirata, Eiji Sugiyama
Publikováno v:
Viruses, Vol 15, Iss 7, p 1498 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), utilizes the host receptor angiotensin-converting enzyme 2 (ACE2) and the auxiliary receptor Neuropilin-1 (NRP1) to enter host cells. NRP1
Externí odkaz:
https://doaj.org/article/ac72665cce074d1789e9e777f1e21a4c
Autor:
Hirofumi Watanabe, Ge Tao, Peiheng Gan, Baylee C. Westbury, Kristie D. Cox, Kelsey Tjen, Ruolan Song, Glenn I. Fishman, Takako Makita, Henry M. Sucov
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 4, p 161 (2023)
Adult hearts are characterized by inefficient regeneration after injury, thus, the features that support or prevent cardiomyocyte (CM) proliferation are important to clarify. Diploid CMs are a candidate cell type that may have unique proliferative an
Externí odkaz:
https://doaj.org/article/d8d4c517d1e44ae3b2d7f98118750785
Autor:
Toshihiro Masuda, Eiji Nakatani, Toshihiro Shirai, Taisuke Akamatsu, Kanami Tamura, Shingo Takahashi, Yuko Tanaka, Hirofumi Watanabe, Yoshinari Endo, Takahito Suzuki, Mika Saigusa, Akito Yamamoto, Satoru Morita, Yoko Sato, Kazuhiro Asada
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background The effectiveness of the 23-valent pneumococcal polysaccharide vaccine (PPSV23) in preventing pneumococcal pneumonia has been controversial. Methods To evaluate the effectiveness of the PPSV23 in elderly outpatients with chronic r
Externí odkaz:
https://doaj.org/article/16d0c4a719574077be4f3dc34fb4e8ce
Autor:
Hirofumi Watanabe, Yuto Yamazaki, Fumiyoshi Fujishima, Komoto Izumi, Masayuki Imamura, Susumu Hijioka, Kazuhiro Toriyama, Yasushi Yatabe, Atsushi Kudo, Fuyuhiko Motoi, Michiaki Unno, Hironobu Sasano
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Streptozocin (STZ) is used for treating both pancreatic (PanNET) and gastrointestinal (GI-NET) neuroendocrine tumors but its therapeutic efficacy is relatively low in GI-NETs. Therefore, it has become pivotal to select GI-NET pati
Externí odkaz:
https://doaj.org/article/9515e351a9c3405ea2b346a87c38e0ce