Výsledky vyhledávání - "Hirofumi Takei"

Tocilizumab monotherapy for large vessel vasculitis: results of 104-week treatment of a prospective, single-centre, open study

Autor: Ryota Sakai, Shuntaro Saito, Ayumi Okuyama, Tsuneo Kondo, Koichi Amano, Yusuke Okada, Takahiko Kurasawa, Hirofumi Takei, A. Shibata

Publikováno v: Rheumatology. 59:1617-1621

Objective To evaluate the efficacy and safety of tocilizumab (TCZ) monotherapy for large vessel vasculitides (LVV), including Takayasu arteritis (TAK) and GCA. Methods Twelve patients with a newly diagnosed LVV (eight GCA, four TAK) were enrolled. On

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d9eb28f8054cc8d67a7b10d49adce8
https://doi.org/10.1093/rheumatology/kez511

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Tocilizumab monotherapy for polymyalgia rheumatica: A prospective, single‐center, open‐label study

Autor: Ayumi Okuyama, Hirofumi Takei, Yusuke Okada, A. Shibata, Tsuneo Kondo, Shuntaro Saito, Koichi Amano, Ryota Sakai, Takahiko Kurasawa, K. Chino

Publikováno v: International Journal of Rheumatic Diseases. 22:2151-2157

Objectives Polymyalgia rheumatica (PMR) is a systemic inflammatory disease in the elderly of unknown etiology. While glucocorticoids are the mainstay of treatment for PMR, various glucocorticoid-related adverse events are common. Recently, several st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fdfb5b6df61a60717c015c15dd018f
https://doi.org/10.1111/1756-185x.13723

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Current clinical evidence of tocilizumab for the treatment of ANCA-associated vasculitis: a prospective case series for microscopic polyangiitis in a combination with corticosteroids and literature review

Autor: Hayato Nagasawa, Eiko Nishi, A. Shibata, Yusuke Okada, Koichi Amano, Hirofumi Takei, Tsuneo Kondo, Ayumi Okuyama, K. Chino, Ryota Sakai, Takahiko Kurasawa

Publikováno v: Clinical Rheumatology. 36:2383-2392

The purpose of this study is to report the efficacy and safety of a combination of tocilizumab (TCZ) and high-dose corticosteroid (CS) in two patients with microscopic polyangiitis (MPA) and review the published current clinical evidence on TCZ in pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d27dfbf835d2b5e149de749c0c1560
https://doi.org/10.1007/s10067-017-3752-0

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Efficacy and safety of multitarget therapy with cyclophosphamide and tacrolimus for lupus nephritis: a prospective, single-arm, single-centre, open label pilot study in Japan

Autor: Yusuke Okada, Eiko Nishi, Koji Nishimura, A. Shibata, Ayumi Okuyama, Hayato Nagasawa, Hirofumi Takei, Kouichi Amano, Takahiko Kurasawa, Tsuneo Kondo, Ryota Sakai, K. Chino

Publikováno v: Lupus. 27:273-282

Background Pulsed cyclophosphamide or mycophenolate mofetil for lupus nephritis has limited efficacy. We previously reported a case of mixed-class IV + V lupus nephritis successfully treated with cyclophosphamide and tacrolimus. This study assessed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f378cae2389575901d6509a667fcb3
https://doi.org/10.1177/0961203317719148

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Successful treatment with tocilizumab monotherapy for Takayasu arteritis developing during infliximab therapy in a patient with ulcerative colitis

Autor: Yusuke Okada, Hirofumi Takei, A. Shibata, Ayumi Okuyama, Takahiko Kurasawa, Shuntaro Saito, Tsuneo Kondo, Ryota Sakai, Koichi Amano, K. Chino

Publikováno v: Modern Rheumatology Case Reports. 2:174-176

A 23-year-old female patient with ulcerative colitis (UC) who had been successfully treated with infliximab (IFX) plus 5-aminosalicylated acid (5-ASA) developed Takayasu arteritis (TAK). She refuse...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5625e8ad1ca637cbb37cf8e8884da349
https://doi.org/10.1080/24725625.2018.1479155

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Corticosteroid-free treatment of tocilizumab monotherapy for microscopic polyangiitis: a single-arm, single-center, clinical trial

Autor: Hirofumi Takei, Jun Kikuchi, Tsuneo Kondo, A. Shibata, Ryota Sakai, Koichi Amano, K. Chino, Ayumi Okuyama

Publikováno v: Modern Rheumatology. 26:900-907

To assess the efficacy of tocilizumab (TCZ) monotherapy for the remission induction of microscopic polyangiitis (MPA) in a prospective single-arm, single-center, cohort, pilot study.Eligible patients were aged between 20 and 80 years and were newly d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1e0c09b3debd4744e56b9aaf36baef
https://doi.org/10.3109/14397595.2016.1160968

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AB0405 Clinical features and problems of elderly onset rheumatoid arthritis in ultra-ageing society –single centre retrospective cohort study

Autor: Yusuke Okada, Ayumi Okuyama, A. Shibata, Kouichi Amano, Hirofumi Takei, Shuntaro Saito, Tsuneo Kondo, Takahiko Kurasawa, K. Chino

Publikováno v: Rheumatoid arthritis – comorbidity and clinical aspects.

Background Japan is the ultra-ageing society ahead of any other country in the world, which ageing rate (the ratio of the population aged 65 and older to the total population) was reported to be 27.3% on October 1, 2016. The rate of aged patients, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3226d1caf5d0028eb2aa27ee46ee6e79
https://doi.org/10.1136/annrheumdis-2018-eular.3589

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FRI0480 Tocilizumab mono-therapy for polymyalgia rheumatica ~ results of 104-week treatment of a prospective, single-centre, open trial

Autor: Ryota Sakai, Hirofumi Takei, Ayumi Okuyama, Yusuke Okada, A. Shibata, Tsuneo Kondo, Shuntaro Saito, Kouichi Amano, K. Chino, Takahiko Kurasawa

Publikováno v: FRIDAY, 15 JUNE 2018.

Background Polymyalgia rheumatic (PMR) is a chronic inflammatory rheumatic disease in the elderly people. Glucocorticoid (GC) is still definitely a mainstay for the treatment of PMR, but long-term GC therapy is a major risk factor of osteoporotic fra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d5c134290255535272f18c5175922ef
https://doi.org/10.1136/annrheumdis-2018-eular.3605

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Efficacy and tolerability of six-week extended dosing interval with tocilizumab therapy in a prospective cohort as remission maintenance in patients with rheumatoid arthritis

Autor: Takahiko Kurasawa, Ryota Sakai, A. Shibata, Yusuke Okada, Koichi Amano, Ayumi Okuyama, Tsuneo Kondo, Hirofumi Takei, Jun Kikuchi, K. Chino

Publikováno v: Modern rheumatology. 28(3)

To prospectively evaluate the efficacy and tolerability of a six-week extended dosing interval with tocilizumab (TCZ) in patients with rheumatoid arthritis (RA) in sustained remission.Patients who received over six doses of intravenous TCZ in clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f62f52adfd9aefe681d3d3b753837c9
https://pubmed.ncbi.nlm.nih.gov/28849709

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