Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Hirofumi Naganuma"'
Publikováno v:
physica status solidi (a). 218:2000535
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 22:132-142
To elucidate the precise recovery process and prognosis of language functions in aphasic patients with left putaminal hemorrhage, we investigated 48 aphasic patients classified into 4 groups according to the location and extent of hematoma. The hemat
Publikováno v:
Journal of Neurosurgery. 105:119-128
Object Malignant glioma cells secrete and activate transforming growth factor–β (TGFβ) and are resistant to growth inhibition by that factor. Nevertheless, the mechanism underlying this effect remains poorly understood. In this study, the mechani
Publikováno v:
Neurologia medico-chirurgica. 46:147-151
A 29-year-old male presented with loss of consciousness and generalized seizure, followed by right hemiparesis and speech disturbance. Computed tomography and magnetic resonance imaging showed a solid, enhanced tumor with a cyst in the left frontal a
Autor:
Shuichiro Maeda, Koro Furuya, Tadashi Mabuchi, Lei Zhang, Hirofumi Naganuma, Arata Watanabe, Eiji Satoh
Publikováno v:
Journal of Neuro-Oncology. 77:25-32
Invasion of tumor cells into the surrounding normal brain tissues is a prominent feature of malignant gliomas. Malignant glioma cells secrete thrombospondin-1 which participates in the motility of glioma cells and binds cell surface heparan sulfate p
Autor:
Koro Furuya, Tomoyuki Kawataki, Tetsu Yamane, Hirofumi Naganuma, Lei Zhang, Kenichi Amagasaki, Eiji Satoh, Hideaki Nukui, Takayuki Asahara
Publikováno v:
Neuropathology. 25:136-143
Five malignant glioma cell lines (YMG1, 2, 3, 4, and 5) were established from surgical specimens obtained from patients with glioblastoma or anaplastic astrocytoma, and these lines were partially characterized. Three glioma cell lines (YMG1, 3, and 5
Autor:
Hiroki Satoh, Katsuhiro Kuroda, Lei Zhang, Takayuki Asahara, Hirofumi Naganuma, Arata Watanabe, Kenichi Amagasaki, Eiji Satoh, Hideaki Nukui
Publikováno v:
Journal of Neuro-Oncology. 70:309-317
Malignant glioma cells secrete thrombospondin-1 (TSP-1) which participates in the motility of glioma cells, and binds to cell surface alphavbeta3 and alpha3beta1 integrins, and syndecan-1. This study evaluated the amount of TSP-1 secretion from malig
Autor:
Hirofumi Naganuma, Masao Sugita, Takayuki Asahara, Eiji Satoh, Satoshi Sakatsume, Hideaki Nukui
Publikováno v:
Neurologia medico-chirurgica. 44:195-200
Two cases of solitary plasmacytomas of the skull are presented, and some biological aspects of the tumor examined. A 75-year-old woman presented with a tumor in the right parietal region. The serum level of immunoglobulin G (IgG) was high and a urine
Autor:
Hiroki Satoh, Eiji Satoh, Tomoyuki Kawataki, Hirofumi Naganuma, Kenichi Amagasaki, Hideaki Nukui
Publikováno v:
Journal of Neuro-Oncology. 63:147-153
Thrombospondin-1 (TSP-1) is a multifunctional matrix protein implicated in cancer cell adhesion, migration, and invasion, inhibition of angiogenesis, and activation of latent transforming growth factor-β (TGF-β). The effect of cell density was inve
Autor:
Hideaki Nukui, Eiji Satoh, Atsushi Sasaki, Tomoyuki Kawataki, Hirofumi Naganuma, Kenichi Amagasaki
Publikováno v:
Neurologia medico-chirurgica. 41:253-259
Malignant glioma cells secrete transforming growth factor-beta (TGF-beta) and can activate latent TGF-beta. However, the mechanism of the latent TGF-beta activation has not yet been determined. This study examined whether thrombospondin-1 (TSP-1) sec