Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hirofumi Morihara"'
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 11, Pp 565-579 (2024)
Abstract Transmembrane protein 182 (TMEM182) is notably abundant in muscle and adipose tissue, but its role in the heart remains unknown. This study examined the contribution of TMEM182 in the differentiation of human induced pluripotent stem cells (
Externí odkaz:
https://doaj.org/article/e59bcd8fe5bd4b7fb5909f743039f676
Autor:
Mime Kobayashi, Kiichiro Tomoda, Hirofumi Morihara, Michio Asahi, Tetsuji Shimizu, Shinya Kumagai
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17585- (2023)
Externí odkaz:
https://doaj.org/article/0c4010b16dae4c97b42555d9b69fda16
Autor:
Mahito Matsuno, Shunichi Yokoe, Takehiro Nagatsuka, Hirofumi Morihara, Kazumasa Moriwaki, Michio Asahi
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
O-GlcNAc transferase (OGT) modulates many functions of proteins via O-GlcNAcylation that adds O-linked β-N-acetylglucosamine (O-GlcNAc) to the serine/threonine residues of proteins. However, the role of O-GlcNAcylation in cardiac remodeling and func
Externí odkaz:
https://doaj.org/article/da8a0d57575f45aaaab0b8210cb8cc44
Autor:
Mime Kobayashi, Kiichiro Tomoda, Hirofumi Morihara, Michio Asahi, Tetsuji Shimizu, Shinya Kumagai
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12009- (2022)
Non-thermal atmospheric-pressure plasma has been used for biological applications, including sterilization and stimulation of cell growth and differentiation. Here, we demonstrate that plasma exposure influences the differentiation pattern of human i
Externí odkaz:
https://doaj.org/article/d8b8c6023f134a76a0034e57c8b463eb
Autor:
Atsushi Daimon, Hirofumi Morihara, Kiichiro Tomoda, Natsuko Morita, Yoshinori Koishi, Kazuyoshi Kanki, Masahide Ohmichi, Michio Asahi
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Miscarriage is the most common complication of pregnancy, and about 1% of pregnant women suffer a recurrence. Using a widely used mouse miscarriage model, we previously showed that intravenous injection of bone marrow (BM)-derived endothelial progeni
Externí odkaz:
https://doaj.org/article/5cb358d66895451998d47b1285bbed0e
Autor:
Hirofumi Morihara, Masanori Obana, Shota Tanaka, Ikki Kawakatsu, Daisuke Tsuchiyama, Shota Mori, Hiroshi Suizu, Akiko Ishida, Rumi Kimura, Izuru Tsuchimochi, Makiko Maeda, Takehiko Yoshimitsu, Yasushi Fujio, Hiroyuki Nakayama
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189948 (2017)
Excessive levels of reactive oxygen species (ROS) and impaired Ca2+ homeostasis play central roles in the development of multiple cardiac pathologies, including cell death during ischemia-reperfusion (I/R) injury. In several organs, treatment with 2-
Externí odkaz:
https://doaj.org/article/7621d1ec32c54fc198e89394bb5cc0dd
Autor:
Reo Matsuo, Hirofumi Morihara, Tomomi Mohri, Shiho Murasawa, Kana Takewaki, Hiroyuki Nakayama, Makiko Maeda, Yasushi Fujio
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111097 (2014)
Interleukin-6 (IL-6) family cytokines play important roles in cardioprotection against pathological stresses. IL-6 cytokines bind to their specific receptors and activate glycoprotein 130 (gp130), a common receptor, followed by further activation of
Externí odkaz:
https://doaj.org/article/23ed3df0f68b4e54826cd1217003b538
Autor:
Hirofumi Morihara, Kenjiro Tsuruoka, Shigeo Wakabayashi, Ninso Matsunaga, Michio Asahi, Akihisa Imagawa, Yasuhito Fujisaka, Isao Goto
Publikováno v:
International Journal of Cardiology. 313:67-75
Background Although immune checkpoint inhibitors (ICIs) have made an immense breakthrough in cancer therapeutics, they can exert unique, immune-related adverse events. Among them, myocarditis is less frequent, but it is serious and often follows a le
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:YIA03-4
Autor:
Kazumasa Moriwaki, Hirofumi Morihara, Shunichi Yokoe, Kiichiro Tomoda, Michio Asahi, Shigeo Wakabayashi, Takatoshi Nakagawa
Publikováno v:
Journal of Biological Chemistry. 294:19577-19588
Understanding the specific properties of human induced pluripotent stem cells (iPSCs) is important for quality control of iPSCs. Having incidentally discovered that overexpression of plasma membrane Na+/H+ exchanger 1 (NHE1) induces cell death in iPS