Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hirofumi Kuwahara"'
Autor:
Mayumi Sakaguchi, Tsuneaki Nakamura, Shinichi Watanabe, Kyoko Ahiko, Akemi Toyoda, Takuya Otoizumi, Hajime Kojima, Kazuhiko Hayashi, Takumi Hayashi, Haruka Goto, Takashi Sozu, Hirofumi Kuwahara, Takashi Morimoto, Takashi Omori, Hitoshi Sakaguchi
Publikováno v:
Toxicology in Vitro. 27:1855-1869
A Short Time Exposure (STE) test is a cytotoxicity test that uses SIRC cells (rabbit corneal cell line) to assess eye irritation potency following a 5-min chemical exposure. This second-phase validation study assessed the predictive capacity of the S
Autor:
Kayoko Matsunaga, Minehiro Okuda, Masatoshi Ito, Hirofumi Kuwahara, Isao Yoshimura, Yuko Okamoto, Fukuyoshi Mori, Shigemi Kinoshita, Keiichi Kawai, Hajime Kojima, Mariko Sugiyama, Kumiko Washizaki, Hirohiko Akamatsu, Norito Katoh, Masaru Natsuaki, Hiromi Kanto
Publikováno v:
The Journal of Dermatology. 40:363-369
We investigated the optimum application for evaluating skin irritation response by using samples of irritants commonly used as additives in cosmetics and other common household products. We studied 47 volunteers (16 men and 31 women). We selected thr
Autor:
Hitoshi Sakaguchi, Mirei Koike, Naohiro Nishiyama, Takumi Hayashi, Yutaka Takahashi, Hirofumi Kuwahara
Publikováno v:
Cutaneous and Ocular Toxicology. 29:77-90
We have developed the short time exposure (STE) test using a rabbit corneal cell line (SIRC cells) as an alternative eye irritation test. The STE test uses relative viability as the endpoint after cells are exposed to the test material at 5%, 0.5%, a
Autor:
Hitoshi Sakaguchi, Kazuhiko Hayashi, Mirei Koike, Takumi Hayashi, Noriko Aisawa, Shinya Ebata, Yutaka Takahashi, Naohiro Nishiyama, Hirofumi Kuwahara, Shinichi Watanabe, Tsuneaki Nakamura
Publikováno v:
The Journal of Toxicological Sciences. 34:611-626
Short time exposure (STE) test using rabbit corneal cell line (SIRC) cells was developed as an alternative eye irritation test. STE test uses relative viability as the endpoint after cells are exposed to the test material at constant concentrations f
Autor:
Yutaka Aoki, Aki Soejima, Hirofumi Kuwahara, Kimio Shimamura, Takeshi Ikemoto, Akinori Haratake
Publikováno v:
Journal of Society of Cosmetic Chemists of Japan. 34:127-133
ワインはぶどうの種類や栽培方法, 醸造方法, 土壌, 天候, 保存方法等により, その味わいが大きく異なることが知られている。それは, 主成分であるα-ヒドロキシ酸・グリセリン・糖類の
Autor:
Yoshiro Hatakeyama, Hirofumi Kuwahara, Fukuyoshi Mori, Takuji Masunaga, Osamu Morita, Yuko Doi, Mayuko Suguro, Fumio Furukawa
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 49(4)
This study was conducted to examine the post-initiation carcinogenic potential of coated and uncoated titanium dioxide nanoparticles (CTDN and UCTDN) using a mouse medium-term skin carcinogenesis bioassay. For this purpose, 5, 10 and 20 mg/animal dos