Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hirofumi Inagaki"'
Autor:
Ying-Ji Li, Takako Shimizu, Yusuke Shinkai, Tomomi Ihara, Masao Sugamata, Katsuhito Kato, Maiko Kobayashi, Yukiyo Hirata, Hirofumi Inagaki, Makoto Uzuki, Toshio Akimoto, Masakazu Umezawa, Ken Takeda, Arata Azuma, Masayuki Yamamoto, Tomoyuki Kawada
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 443 (2020)
In the present study, we investigated the role of Nrf2 in airway immune responses induced by diesel exhaust (DE) inhalation in mice. C57BL/6J Nrf2+/+ and Nrf2−/− mice were exposed to DE or clean air for 8 h/day and 6 days/week for 4 weeks. After
Externí odkaz:
https://doaj.org/article/682c858f519a442ea950725793e6f5d3
Autor:
Katsunori Kobayashi, Yumiko Ikeda, Minoru Asada, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuki
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63662 (2013)
The hippocampal dentate gyrus has been implicated in a neuronal basis of antidepressant action. We have recently shown a distinct form of neuronal plasticity induced by the serotonergic antidepressant fluoxetine, that is, a reversal of maturation of
Externí odkaz:
https://doaj.org/article/6aca2915e1f84b9d90ce0e5275fe4727
Publikováno v:
BioScience Trends. Apr2014, Vol. 8 Issue 2, p126-131. 6p.
Autor:
Fumihito Saitow, Kazuo Kitamura, Yasuyoshi Watanabe, Toru Takumi, Masatoshi Nagano, Jin Nakatani, Yoshinobu Kawamura, Hiroshi Mizuma, Tomoyuki Kawada, Nobuhiro Nakai, Taisuke Miyazaki, Hajime Hirase, Hirotaka Onoe, Shigeo Okabe, Yasuhito Watanabe, Akiko Kawamoto, Yuka Sato, Kota Tamada, Masahiko Watanabe, Hiromu Monai, Masanobu Kano, Hidenori Suzuki, Hirofumi Inagaki, Kouichi Hashimoto
Publikováno v:
Science Advances
Serotonin enhancement during developmental stages restores autism symptoms in a mouse model of human 15q11-13 duplication.
Serotonin is a critical modulator of cortical function, and its metabolism is defective in autism spectrum disorder (ASD)
Serotonin is a critical modulator of cortical function, and its metabolism is defective in autism spectrum disorder (ASD)
Publikováno v:
BioScience Trends. 8:126-131
Granzyme 3 (Gr3) is known as a tryptase-type member of the granzyme family and exists in the granules of immunocompetent cells. Granule proteases including granzymes, are transported into the cytoplasm of tumor cells or virus-infected cells by perfor
Autor:
Satoshi Omura, Hirofumi Inagaki, Takako Shimizu, Hajime Takizawa, Shoji Kudoh, Tomoyuki Kawada, Ying-Ji Li, Toshiaki Sunazuka, Yukiyo Hirata, Isamu Sugawara, Arata Azuma
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 26:318-324
Diesel exhaust particle (DEP) is the major components of PM2.5, and much attention has focused on PM2.5 in relation to adverse health effects, and many pulmonary diseases. In the present study, we used a human bronchial epithelial cell (HBEC) line to
Publikováno v:
Diabetesmetabolic syndrome. 11(3)
Aims The authors identified the risk of disorders of glucose metabolism (DGM) for sleep-disordered breathing (SDB). Methods We conducted a cross-sectional study in 536 men aged 33–84 years. Patients with diabetes medication were excluded for the an
Publikováno v:
Neuropharmacology. 63:292-300
Many psychiatric disorders emerge after adolescence. Among a variety of predisposing factors, prenatal stress has been thought to cause the symptoms of anxiety disorders. We recently reported that prenatal dexamethasone (DEX) exposure, which mimics s
Autor:
Toshihiro Kawamoto, Megumi Suda, Kimiko Hirata, Tomoyuki Kawada, Maiko Kobayashi, Takako Shimizu, Qing Li, Tamie Nakajima, Wang Rs, Yukiyo Hirata, Hirofumi Inagaki
Publikováno v:
International Journal of Immunopathology and Pharmacology. 24:837-847
Ethyl tertiary-butyl ether (ETBE) is a motor fuel oxygenate used in reformulated gasoline. The current use of ETBE in gasoline or petrol is modest but increasing. To investigate the effects of ETBE on splenocytes, mice were exposed to 0 (control), 50
Autor:
Hirotsugu Miyake, Hideyo Takahashi, Kazuhiro Sakai, Shun Matsumoto, Tsukasa Sasaki, Yuko Yamano, Hirofumi Inagaki, Masayasu Minami
Publikováno v:
Environmental Health and Preventive Medicine. 17:87-97
The effect of a severely stressful situation (sleep restriction and psychological load) on the diurnal changes in novel tryptamine-related compounds (hydroxydiacetyltryptamine, sulphatoxymelatonin, and dihydromelatonin) was evaluated in human subject