Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Hirofumi Hirao"'
Autor:
Kentaro Kadono, Hidenobu Kojima, Siyuan Yao, Shoichi Kageyama, Kojiro Nakamura, Hirofumi Hirao, Takahiro Ito, Kenneth J. Dery, Douglas G. Farmer, Fady M. Kaldas, Xiaoling Li, Jerzy W. Kupiec-Weglinski
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-12 (2023)
Abstract Sirtuin 1 (SIRT1) is a histone/protein deacetylase in the cellular response to inflammatory, metabolic, and oxidative stressors. We previously reported that myeloid SIRT1 regulates the inflamed liver’s canonical pyroptosis cell death pathw
Externí odkaz:
https://doaj.org/article/3a5403bafd664af48bce0be497bd111f
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
Externí odkaz:
https://doaj.org/article/fdb49f5f39664b43a04d4d93d4ab9ddd
Autor:
Hirofumi Hirao, Shoichi Kageyama, Kojiro Nakamura, Kentaro Kadono, Hidenobu Kojima, Yao Siyuan, Douglas G. Farmer, Fady M. Kaldas, Kenneth J. Dery, Jerzy W. Kupiec-Weglinski
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
T-cell immunoglobulin and mucin (Tim)4 is expressed on APCs, including macrophages, as one of the main amplifiers in the mechanism of liver ischemia-reperfusion injury (IRI) following orthotopic liver transplantation (OLT). Though donor Tim4 selectiv
Externí odkaz:
https://doaj.org/article/aa45fc08703d486b84c22e397c3d50e8
Autor:
Paulina Podkalicka, Olga Mucha, Katarzyna Kaziród, Krzysztof Szade, Jacek Stępniewski, Liudmyla Ivanishchuk, Hirofumi Hirao, Ewelina Pośpiech, Alicja Józkowicz, Jerzy W. Kupiec-Weglinski, Józef Dulak, Agnieszka Łoboda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Although Duchenne muscular dystrophy (DMD) primarily affects muscle tissues, the alterations to systemic metabolism manifested in DMD patients contribute to the severe phenotype of this fatal disorder. We propose that microRNA-378a (miR-378)
Externí odkaz:
https://doaj.org/article/31f8767de0804f9ea3cdfb34755154d9
Autor:
Hirofumi Hirao, Hidenobu Kojima, Kenneth J. Dery, Kojiro Nakamura, Kentaro Kadono, Yuan Zhai, Douglas G. Farmer, Fady M. Kaldas, Jerzy W. Kupiec-Weglinski
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Neutrophils, the largest innate immune cell population in humans, are the primary proinflammatory sentinel in the ischemia-reperfusion injury (IRI) mechanism in orthotopic liver transplantation (OLT). Carcinoembryonic antigen–related cell adhesion
Externí odkaz:
https://doaj.org/article/a597728125524ce19b0ebe42471aea24
Publikováno v:
Nature Reviews Gastroenterology & Hepatology. 19:239-256
Liver ischaemia-reperfusion injury (LIRI), a local sterile inflammatory response driven by innate immunity, is one of the primary causes of early organ dysfunction and failure after liver transplantation. Cellular damage resulting from LIRI is an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b7ebbd2d21c1dd4937f0ca2162b09d3
https://doi.org/10.1038/s41575-021-00549-8
https://doi.org/10.1038/s41575-021-00549-8
Publikováno v:
Antioxidantsredox signaling.
Innate and adaptive immune responses regulate hepatic ischemia-reperfusion injury (IRI) in orthotopic liver transplantation (OLT). While the mechanism of how nuclear factor erythroid 2-related factor 2 (NRF2) plays a critical role in liver IRI has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e435e778ecbf3a5fc175a12d23009a8
https://pubmed.ncbi.nlm.nih.gov/36070449
https://pubmed.ncbi.nlm.nih.gov/36070449
Autor:
Ronald W. Busuttil, Jerzy W. Kupiec-Weglinski, Fady M. Kaldas, Hirofumi Hirao, Kentaro Kadono, Shoichi Kageyama, Bita V. Naini, Hidenobu Kojima, Kojiro Nakamura, Takahiro Ito
Publikováno v:
Hepatology. 74:2759-2773
BACKGROUND AND AIMS Environmentally triggered chronic liver inflammation can cause collagen deposits, whereas early stages of fibrosis without any specific symptoms could hardly be detectable. We hypothesized that some of the human donor grafts in cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab50bc274367f1e4dfaafab5b965a707
https://doi.org/10.1002/hep.32030
https://doi.org/10.1002/hep.32030
Autor:
Takeshi Watanabe, Kenichi Saga, Hiroaki Terajima, Shinji Uemoto, Kentaro Kadono, Shugo Ueda, Yoichiro Uchida, Junya Kawasoe, Tomoyuki Miyauchi, Hirofumi Hirao
Publikováno v:
American Journal of Transplantation
Ischemia and reperfusion injury (IRI) can occur in any tissue or organ. With respect to liver transplantation, the liver grafts from donors by definition experience transient ischemia and subsequent blood reflow. IRI is a problem not only in organ tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5990f9da7cf2d94409dd805d371d5a50
http://hdl.handle.net/2433/277837
http://hdl.handle.net/2433/277837
Autor:
Takahiro Ito, Ronald W. Busuttil, Jerzy W. Kupiec-Weglinski, Hidenobu Kojima, Kentaro Kadono, Kojiro Nakamura, Kenneth J. Dery, Hirofumi Hirao, Shoichi Kageyama, Fady M. Kaldas
Publikováno v:
Hepatology (Baltimore, Md.)
Hepatology (Baltimore, Md.), vol 72, iss 3
Hepatology (Baltimore, Md.), vol 72, iss 3
Author(s): Dery, Kenneth J; Nakamura, Kojiro; Kadono, Kentaro; Hirao, Hirofumi; Kageyama, Shoichi; Ito, Takahiro; Kojima, Hidenobu; Kaldas, Fady M; Busuttil, Ronald W; Kupiec-Weglinski, Jerzy W | Abstract: Background and aimsIschemia-reperfusion inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800ca9a0a4e53005a8a00f490706cc06
http://europepmc.org/articles/PMC8330638
http://europepmc.org/articles/PMC8330638