Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hirofumi, Yamauchi"'
Autor:
Yuichi Shiraishi, Ai Okada, Kenichi Chiba, Asuka Kawachi, Ikuko Omori, Raúl Nicolás Mateos, Naoko Iida, Hirofumi Yamauchi, Kenjiro Kosaki, Akihide Yoshimi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
This paper proposed a novel in-silico framework for automatically screening disease-related variants and applied it to over 200,000 transcriptomes, providing an example to acquire medically relevant knowledge from publicly available sequence data.
Externí odkaz:
https://doaj.org/article/02ab6b33e13246a8bb0ad1e5da9d463b
Autor:
Hirofumi Yamauchi, Mamiko Momoki, Yutaro Kamiyama, Tadahiro Gunji, Hiroki Yokoyama, Takeshi Saito, Boutbou, David, Oksenhendler, Eric, Shingo Yano
Publikováno v:
Internal Medicine; 2024, Vol. 54 Issue 7, p993-998, 6p
Publikováno v:
Cancer Science. 113:373-381
There has been accumulating evidence that RNA splicing is frequently dysregulated in a variety of cancers and that hotspot mutations affecting key splicing factors, SF3B1, SRSF2 and U2AF1, are commonly enriched across cancers, strongly suggesting tha
Autor:
Ai Okada, Kenjiro Kosaki, Akihide Yoshimi, Hirofumi Yamauchi, Raúl Nicolás Mateos, Naoko Iida, Ikuko Omori, Yuichi Shiraishi, Kenichi Chiba
Many disease-associated genomic variants disrupt gene function through abnormal splicing. With the advancement of genomic medicine, identifying disease-associated splicing associated variants has become more important than ever. Most bioinformatics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::676d3dcd50c1e24131a58a583a12e401
https://doi.org/10.1101/2021.10.05.463278
https://doi.org/10.1101/2021.10.05.463278
Autor:
Kei-ichi Katayama, Masaki Ueno, Hirofumi Yamauchi, Takayuki Nagata, Hiroyuki Nakayama, Kunio Doi
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 218-225 (2005)
Neural progenitor cells populate the ventricular zone of the fetal central nervous system. In this study, immediately after the administration of ethylnitrosourea (ENU), an alkylating agent, an accumulation of neural progenitor cells in the S phase w
Externí odkaz:
https://doaj.org/article/212f5e34b1a14dfe8bfc0f5c7739d599
Publikováno v:
Journal of pharmacological and toxicological methods. 112
Administration of a compound can induce drug-metabolizing enzymes (DMEs) in the liver. DME induction can affect various parameters in toxicology studies. Therefore, evaluation of DME induction is important for interpreting test compound-induced biolo
Autor:
Naoko Tsuyama, Naoki Mori, Kengo Takeuchi, Hirofumi Yamauchi, Noriko Nishimura, Tetsuya Ogawa, Masahiro Yokoyama, Shoko Marshall, Norihito Inoue, Hiroshi Sakura, Yasuhito Terui, Yuko Mishima, Toshie Ogasawara
Publikováno v:
Clinical lymphoma, myelomaleukemia. 21(3)
The R-CHOP regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) is the standard therapy for patients with diffuse large B-cell lymphoma (DLBCL). However, vincristine is sometimes omitted or reduced owing to side effects.W
Autor:
Kengo Takeuchi, Naoko Tsuyama, Masahiro Yokoyama, Norihito Inoue, Yuji Mishima, Kiyohiko Hatake, Yoshiharu Kusano, Yasuhito Terui, Anna Takahashi, Yuko Mishima, Hirofumi Yamauchi, Kyoko Ueda, Noriko Nishimura
Publikováno v:
British Journal of Haematology. 183:661-664
Autor:
Yuko, Shiota, Nobuaki, Dobashi, Yuta, Ito, Rika, Hosoba, Hirofumi, Yamauchi, Hiroto, Ishii, Aya, Nakano, Ryoko, Fukushima, Rie, Ohba, Yuichi, Yahagi, Noriko, Usui, Shingo, Yano
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 60(2)
Primary central nervous system lymphoma (PCNSL) is a rare, aggressive type of non-Hodgkin lymphoma with a poor prognosis and no defined optimal therapeutic strategies. We retrospectively analyzed the survival of six PCNSL patients who were treated wi
Publikováno v:
Experimental and Molecular Pathology. 100:434-440
The present study was carried out to clarify the mechanisms of EMC virus-induced sialodacryoadenitis in mice during the acute phase infection focusing on the activation of type I interferon (IFN) signaling in the parotid and exorbital lachrymal gland