Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Hiroetsu, Suzuki"'
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251135 (2021)
BackgroundSodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used to reduce hyperglycemia. The present study investigated the effects of a SGLT2 inhibitor, empagliflozin, on hyperglycemia in a novel rat model of non-obesity type 2 diabetes
Externí odkaz:
https://doaj.org/article/7a40a4948b73485584bbc6c3ec61bdd7
Autor:
Michele Iacomino, Simona Baldassari, Yuki Tochigi, Katarzyna Kośla, Francesca Buffelli, Annalaura Torella, Mariasavina Severino, Dario Paladini, Luana Mandarà, Antonella Riva, Marcello Scala, Ganna Balagura, Andrea Accogli, Vincenzo Nigro, Carlo Minetti, Ezio Fulcheri, Federico Zara, Andrzej K. Bednarek, Pasquale Striano, Hiroetsu Suzuki, Vincenzo Salpietro
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Mutations in the WWOX gene cause a broad range of ultra-rare neurodevelopmental and brain degenerative disorders, associated with a high likelihood of premature death in animal models as well as in humans. The encoded Wwox protein is a WW domain-cont
Externí odkaz:
https://doaj.org/article/ecbe59a5266242c5aee1486744a8d003
Publikováno v:
Biology, Vol 10, Iss 7, p 633 (2021)
The kidneys participate in the regulation of systemic glucose metabolism via gluconeogenesis, insulin degradation, and the tubular reabsorption of glucose. The present study characterized rats from a strain of a novel type 2 diabetes model with enlar
Externí odkaz:
https://doaj.org/article/dd8769e443d54485a387d898646f18b1
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
A variety of animal models of diabetes mellitus (DM) are required to study the genetics and pathophysiology of DM. We established a novel rat strain showing nonobese type 2 diabetes with enlarged kidneys from the LEA.PET-pet congenic strain and named
Externí odkaz:
https://doaj.org/article/473ab5aa5da8434aa068caf639811084
Autor:
Yoshiki Murakami, Marina Otsuka, Kazuyuki Suzuki, Mitsuhide Nakagawa, Hiroetsu Suzuki, Kenji Tsukano
Publikováno v:
The Journal of Veterinary Medical Science
The aim of this study was to examine whether 2.16% hypertonic saline solution (HSS) is useful for the treatment of diarrheic calves with hyponatremia. Eleven of 13 female Holstein calves exhibiting moderate diarrhea and hyponatremia received 1,250 ml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fff9715f40ae302683df430ee1068ba
https://doi.org/10.1292/jvms.20-0286
https://doi.org/10.1292/jvms.20-0286
Autor:
Kentaro Katayama, Ayaka Domon, Abdullah Al Mahmud, Hiroetsu Suzuki, Yuki Tochigi, Maki Noguchi
Publikováno v:
J Histochem Cytochem
A well-known putative tumor suppressor WW domain–containing oxidoreductase (Wwox) is highly expressed in hormonally regulated tissues and is considered important for the normal development and function of reproductive organs. In this study, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cf85d51d314a8aaa3b3ed181ddcdec
https://pubmed.ncbi.nlm.nih.gov/33565365
https://pubmed.ncbi.nlm.nih.gov/33565365
Publikováno v:
Experimental and Toxicologic Pathology. 69:245-258
A congenital reduction in the number of nephrons is a critical risk factor for both onset of chronic kidney disease (CKD) and its progression to end-stage kidney disease (ESKD). Hypoplastic kidney (HPK) rats have only about 20% of the normal number o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3254d59499302d7fba7dc1e2bc3a2f4
https://doi.org/10.1016/j.etp.2017.01.007
https://doi.org/10.1016/j.etp.2017.01.007
Autor:
Akira Kawaguchi, Kazumasa Shimizu, Takeharu Kaneda, Tsuyoshi Tajima, Hiroetsu Suzuki, Hidenori Kanda, Noriyasu Sasaki, Norimoto Urakawa
Publikováno v:
Journal of Veterinary Medical Science. 79:593-601
Recent studies have shown that phloridzin, an inhibitor of sodium-glucose cotransporter (SGLT), strongly decreases high K+-induced contraction in phasic muscle, such as tenia coli, but slightly affects tonic muscle, such as trachea . In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8586c01ff618442100d8268737d8d4f8
https://doi.org/10.1292/jvms.16-0560
https://doi.org/10.1292/jvms.16-0560
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Journal of Diabetes Research
Journal of Diabetes Research
A variety of animal models of diabetes mellitus (DM) are required to study the genetics and pathophysiology of DM. We established a novel rat strain showing nonobese type 2 diabetes with enlarged kidneys from the LEA.PET-pet congenic strain and named
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0299ccc62d2b23c36a236deac43c41
https://doaj.org/article/473ab5aa5da8434aa068caf639811084
https://doaj.org/article/473ab5aa5da8434aa068caf639811084
Autor:
Hiroetsu, Suzuki, Kumi, Daigo, Mika, Okada, Mio, Yagi, Eijiro, Nakamiya, Kenichi, Saito, Katsushi, Suzuki
Publikováno v:
Reproductive medicine and biology. 5(3)
Background and Aims: The hypogonadic rat (hgn/hgn) shows male sterility controlled by a single recessive gene hgn. The hgn/hgn females detected by the presence of renal hypoplasia in the HGN inbred strain show a reduced fertility. Recently, the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::744930273a85a0b7d7c95a5b4f612a27
https://pubmed.ncbi.nlm.nih.gov/29662400
https://pubmed.ncbi.nlm.nih.gov/29662400