Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Hiroe, Nakazawa"'
Autor:
Minako Hoshiai, Hiroe Nakazawa, Yu Eguchi, Naoko Higashijima, Shinpei Nakazawa, Hideyuki Ishida, Takako Toda, Toshie Kadono
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H3517-H3523
The Na+/H+ exchanger (NHE) inhibitor cariporide has a cardioprotective effect in various animal models of myocardial ischemia-reperfusion. Recent studies have suggested that cariporide interacts with mitochondrial Ca2+ overload and the mitochondrial
Autor:
Takako Toda, Hiroe Nakazawa, Hideyuki Ishida, Keiichi Koizumi, Kenji Ohyama, Shinpei Nakazawa, Hisashi Sugiyama, Minako Hoshiai, Atsushi Naito
Publikováno v:
Circulation Journal. 71:796-801
Background The aim of the present study was to examine whether stanniocalcin 1 (STC1) affects cardiomyocytes under physiological or pathophysiological conditions. Methods and Results Using fresh isolated rat cardiomyocytes, the effects of STC1 on cel
Autor:
Kaori Kudo, Yu Eguchi, Noriaki Wakana, Chizuko Tsuji, Hikari Ohazama, Hiroe Nakazawa, Kazuhiro Homma, Naoto Fukuyama, Asako Suyama, Etsuro Tanaka, Kazuo Ishiwata
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
In most clinical laboratories, low density lipoprotein (LDL) cholesterol is usually estimated indirectly with the Friedewald equation or directly with the N-geneous assay. We assessed LDL-cholesterol values obtained by both methods to find an appropr
Publikováno v:
Thyroid. 16:357-360
Thyroid hormone (triiodothyronine [T(3)]) has various nongenomic effects, including alterations in glucose and fatty acid metabolism, augmentation of intracellular Ca(2+), enhancement of myocardial contractility, and vascular dilatation. However, its
Autor:
Kazuhiro Honma, Hikari Ohazama, Etsuro Tanaka, Kaori Kudo, Asako Suyama, Takaki Damatsu, Hiroe Nakazawa
Publikováno v:
Health evaluation and promotion. 32:429-433
血中LDLコレステロール値測定にはFriedewaldの式による計算法に対し, 近年直接測定する方法 (直接法) が開発されたがその普及率はいまだ高くない。また, 健診前夜の夕食の種類による血清
Autor:
Takeo Tanaami, Hideyuki Ishida, Hiroe Nakazawa, Hidetaka Seguchi, Yuki Hirota, William H. Barry, Toshie Kadono, Chokoh Genka
Publikováno v:
The Japanese Journal of Physiology. 55:81-91
Intracellular [Ca2+] ([Ca2+]i) was imaged in atrial and ventricular rat myocytes by means of a high-speed Nipkow confocal microscope. Atrial myocytes with an absent t-tubule system on 8-di- ANEPPS staining showed an initial rise in Ca2+ at the periph
Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet
Autor:
Yi Chen, Yasunori Okada, Naoto Fukuyama, Hiroe Nakazawa, Chizuko Tsuji, Tetsuya Mine, Shinkichi Sato, Yoichi Ogushi, Shigenari Hozawa, Sadaaki Sawamura, Ryuzaburo Tanino
Publikováno v:
Biochemical and Biophysical Research Communications. 326:45-51
The role of inducible nitric oxide synthase (iNOS) in the progression of fibrosis during nonalcoholic steatohepatitis remains to be elucidated. This study examined the role of iNOS in the progression of fibrosis during steatohepatitis by comparing iN
Autor:
Yuki Hirota, Haruaki Nakaya, Hiroe Nakazawa, Hideyuki Ishida, Toshiaki Sato, Chokoh Genka, Naoko Higashijima
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 369:192-197
The anti-anginal drug nicorandil has been demonstrated to protect the myocardium against ischemic injury in both experimental and clinical studies. Although nicorandil seems to protect the myocardium via activation of mitochondrial ATP-sensitive K+ (
Autor:
Naoto Fukuyama, Koji Kimura, Kazuo Ishiwata, Kiyotaka Hoshiai, Koji Ichimori, Takahiko Yoshida, Ruriko Obama, Hiroe Nakazawa, Hongxu Meng
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 33:61-67
The hypotheses that nitrotyrosine formation is a downstream mechanism following TNF-α production in lipopolysaccharide (LPS)-induced liver injury and its inhibition reduces the injury were examined. Under anesthesia, experiments were performed 6h af
Publikováno v:
Pathophysiology. 9:89-95
We investigated the effectiveness of supportive therapy with a fish-oil extract called repair tuberculosis (RTB) in anti-tuberculosis treatment, and the underlying mechanism of action. The active component of RTB is the unsaturated fatty acid docosat