Výsledky vyhledávání - "Hirobumi Saitoh"

Hypoxia-inducible microRNA-210 regulates the DIMT1-IRF4 oncogenic axis in multiple myeloma

Autor: Akihiro Kitadate, Yoshiaki Hatano, Sho Ikeda, Yoshihiro Michishita, Fumito Abe, Atsushi Kitabayashi, Masaaki Kume, Hiroyuki Tagawa, Naoto Takahashi, Yoshinari Kawabata, Hirobumi Saitoh, Kazuaki Teshima

Publikováno v: Cancer Science

Multiple myeloma (MM) is characterized by the accumulation of a population of malignant plasma cells within the bone marrow and its microenvironment. A hypoxic niche is located within the microenvironment, which causes myeloma cells to become quiesce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9b99d61b316ec5eb1400c21ba66fd9
https://doi.org/10.1111/cas.13183

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CDR3-independent expansion of Vδ1 T lymphocytes in acquired chronic pure red cell aplasia

Autor: Naoto Takahashi, Naohito Fujishima, Yong-Mei Guo, Yoshihiro Michishita, Hirobumi Saitoh, Tomoko Yoshioka, Hiroyuki Tagawa, Jiajia Liu, Masumi Fujishima, Kumi Ubukawa, Kenichi Sawada, Makoto Hirokawa, Yukiko Abe, Yoshihiro Kameoka

Publikováno v: Immunology Letters. 150:23-29

Although there exist case reports describing the association of clonal expansion of γδ T cells with chronic acquired pure red cell aplasia (PRCA), there is no consensus regarding whether clonal expansion of γδ T cells are generally found in chron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9400555b5d6c53141eec11e80c86d025
https://doi.org/10.1016/j.imlet.2012.12.006

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Effect of itraconazole on the concentrations of tacrolimus and cyclosporine in the blood of patients receiving allogeneic hematopoietic stem cell transplants

Autor: Masatomo Miura, Yoshihiro Kameoka, Naohito Fujishima, Hideaki Kagaya, Hiroyuki Tagawa, Naoto Takahashi, Takenori Niioka, Kenichi Sawada, Makoto Hirokawa, Miho Nara, Hirobumi Saitoh

Publikováno v: European Journal of Clinical Pharmacology. 69:1321-1329

The purpose of this study was to investigate the interactions of itraconazole (ITCZ) with orally administered calcineurin inhibitors (CNIs) in Japanese allogeneic hematopoietic stem cell transplant (HSCT) recipients. Sixteen HSCT patients (8 patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f67bd15717c8fbd656710d9f6378b9
https://doi.org/10.1007/s00228-013-1471-2

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Varicella-Zoster Virus-associated Fulminant Hepatitis Following Allogeneic Hematopoietic Stem Cell Transplantation for Multiple Myeloma

Autor: Hiroshi Nanjo, Kenichi Sawada, Hirobumi Saitoh, Naoto Takahashi, Makoto Hirokawa, Yoshinari Kawabata

Publikováno v: Internal Medicine. 52:1727-1730

Disseminated visceral varicella-zoster virus (VZV) infection rarely occurs in recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT). To date, only a few cases of isolated VZV-induced fulminant hepatitis following allo-HSCT have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f5eea942aafd793ca636bb5da0538d
https://doi.org/10.2169/internalmedicine.52.0118

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Safety and efficacy of low-dose liposomal amphotericin B as empirical antifungal therapy for patients with prolonged neutropenia

Autor: Hirobumi Saitoh, Kazuaki Teshima, Naoto Takahashi, Seiji Shida, Isuzu Ito, Kenichi Sawada, Naohito Fujishima, Sho Ikeda, Takayo Nagao, Yoshihiro Kameoka, Shinsuke Noguchi, Makoto Hirokawa, Takaya Yamashita, Hiroyuki Tagawa, Yoshihiro Michishita, Masumi Fujishima, Mitsugu Ito, Hideaki Ohyagi

Publikováno v: International Journal of Clinical Oncology. 18:983-987

Liposomal amphotericin B (L-AmB) is recommended as an empirical antifungal treatment for patients at increased risk of fungal infections although renal toxicity remains a clinical problem. We therefore conducted a pilot study to evaluate the safety a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5daa110128001e19ac5ac1dfbebddd6
https://doi.org/10.1007/s10147-012-0485-6

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Drug interaction of (S)-warfarin, and not (R)-warfarin, with itraconazole in a hematopoietic stem cell transplant recipient

Autor: Masatomo Miura, Hiroyuki Tagawa, Naohito Fujishima, Hirobumi Saitoh, Kenichi Sawada, Syu-ichi Kanno, Mitsugu Itoh, Tomoko Yoshioka, Naoto Takahashi, Miho Nara, Makoto Hirokawa, Shoutaro Kato, Yoshihiro Kameoka

Publikováno v: Clinica Chimica Acta. 412:2002-2006

Background Itraconazole is a potent inhibitor of CYP3A4 and P-glycoprotein, but not CYP2C9. Herein, we report a case study in which the plasma concentration of the CYP2C9 substrate ( S )-warfarin, and not the CYP3A4 substrate ( R )-warfarin, increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fe7ec98790500909e5fa689d829062
https://doi.org/10.1016/j.cca.2011.06.035

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Successful Treatment of Necrotizing Fasciitis in an Upper Extremity Caused by Clostridium perfringens after Bone Marrow Transplantation

Autor: Naohito Fujishima, Shin Yamada, Hiroshi Tazawa, Yoshihiro Kameoka, Takayo Nagao, Naoto Takahashi, Hirobumi Saitoh, Mitsugu Ito, Kenichi Sawada, Takashi Minato, Masaaki Kume, Hiroyuki Tagawa, Seiji Shida, Makoto Hirokawa

Publikováno v: Internal Medicine. 50:2213-2217

We report a 47-year-old man with acute leukemia who survived a severe case of necrotizing fasciitis caused by Clostridium perfringens involving his right upper extremity. On day 5 after stem cell transplantation, progressive local tissue necrosis led

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fb1e0c7e875d5dad654109506068e8
https://doi.org/10.2169/internalmedicine.50.5829

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Thrombotic Thrombocytopenic Purpura with Severe ADAMTS-13 Deficiency in a Patient with Antiphospholipid Antibodies and Charcot-Marie-Tooth Disease

Autor: Hirobumi Saitoh, Kenichi Sawada, Hideki Wakui, Mitsugu Ito, Rie Masai, Naoto Takahashi, Mayu Kosaka, Ryuta Sato

Publikováno v: Internal Medicine. 50:487-493

A 26-year-old woman with a history of mild mental retardation, Charcot-Marie-Tooth disease (CMT) and idiopathic thrombocytopenic purpura developed severe thrombocytopenia with Coombs-negative hemolytic anemia. Magnetic resonance imaging revealed a fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e43b1c934d9783eb8f9207d9b6a54f
https://doi.org/10.2169/internalmedicine.50.4300

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Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia

Autor: Yoshihiro Kameoka, Naohito Fujishima, Hiroyuki Tagawa, Tomoko Yoshioka, Makoto Hirokawa, Kenichi Sawada, Masatomo Miura, Hideaki Kagaya, Naoto Takahashi, Stuart A. Scott, Hirobumi Saitoh

Publikováno v: Journal of Human Genetics. 55:731-737

Imatinib mesylate (IM) trough concentration varies among IM-treated chronic myeloid leukemia (CML) patients. Although IM pharmacokinetics is influenced by several enzymes and transporters, little is known about the role of pharmacogenetic variation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d76a370f4ac96a3ec84a4125ef5565a
https://doi.org/10.1038/jhg.2010.98

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