Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hiroaki Yoshizaki"'
Autor:
Yoshiyuki Fukase, Teruo Kirikae, Fumiko Kirikae, Shoichi Kusumoto, Wen-Chi Liu, Yasuo Suda, Koichi Fukase, Motohiro Kurosawa, Hiroaki Yoshizaki, Masato Oikawa
Publikováno v:
Bulletin of the Chemical Society of Japan. 74:2189-2197
Both endotoxic and antagonistic [ 3 H]-labeled 2-(phosphonooxy)ethyl (PE) analogs of lipid A were synthesized with high purity and high specific radioactivity. Lipid A-binding proteins were detected by using the endotoxic analog of hexaacyl Escherich
Autor:
Hiroaki Yoshizaki, Keonil Lee, Koichi Fukase, Shoichi Kusumoto, Masato Oikawa, Seiji Adachi, Tetsuya Shintaku
Publikováno v:
Bulletin of the Chemical Society of Japan. 74:1455-1461
During the course of a conformational study of lipid A, which is a bioactive entity of lipopolysaccharide of the Gram-negative bacterial cell surface, the molecular conformation of its tetraacyl biosynthetic precursor in dimethyl sulfoxide was unambi
Autor:
Hiroaki Yoshizaki, Naohiro Fukuda, Masato Oikawa, Shoichi Kusumoto, Yasuo Suda, K. Sato, Koichi Fukase
Publikováno v:
Angewandte Chemie. 113:1523-1528
Three sequential efficient glycosylation reactions starting from D-glucosamine were used in the first total synthesis of Escherichia coli Re lipopolysaccharide, which is one of the most simple lipopolysaccharides found on the surface of living bacter
Autor:
Tomohiko Ogawa, Masato Oikawa, Yasuo Suda, Shoichi Kusumoto, Hiroaki Yoshizaki, Yasuhiro Sakai, Koichi Fukase
Publikováno v:
Tetrahedron Letters. 41:6843-6847
Synthesis of lipid A 1 isolated from Helicobacter pylori strain 206-1 has been achieved in 2.2% total yield through 14 steps from d -glucosamine by employing a p-(trifluoromethyl)benzyl group for protection of the hydroxy group on the 3-hydroxy fatty
Autor:
Yoshiyuki Fukase, Yasuo Suda, Tetsuya Shintaku, Masato Oikawa, Shoichi Kusumoto, Hiroaki Yoshizaki, Wen-Chi Liu, Koichi Fukase, Harald Sekljic
Publikováno v:
Journal of Endotoxin Research. 5:46-51
In order to investigate precise structural requirements for expression of the biological activity of lipid A, new structural analogs were synthesized via improved, highly efficient preparative routes. The number and chain length of the fatty acyl gro
Publikováno v:
Synlett. 1998:757-760
Publikováno v:
Bulletin of the Chemical Society of Japan. 70:1435-1440
A biosynthetic precursor of lipid A has been synthesized by an improved efficient method. Two appropriately modified acyl-substituted glucosamine units were synthesized from D-glucosamine using (R)-3-(benzyloxy)tetradecanoic acid and then coupled by
Publikováno v:
ChemInform. 29
Autor:
Masato Oikawa, Harald Sekljic, Hiroaki Yoshizaki, Wen-Chi Liu, Shoichi Kusumoto, Koichi Fukase, Tetsuya Shintaku, Yasuo Suda, Yoshiyuki Fukase
Publikováno v:
ChemInform. 31
In order to investigate precise structural requirements for expression of the biological activity of lipid A, new structural analogs were synthesized via improved, highly efficient preparative rout...
Autor:
K. Sato, Hiroaki Yoshizaki, Shoichi Kusumoto, Koichi Fukase, Yasuo Suda, Masato Oikawa, Naohiro Fukuda
Publikováno v:
ChemInform. 32
Three sequential efficient glycosylation reactions starting from D-glucosamine were used in the first total synthesis of Escherichia coli Re lipopolysaccharide, which is one of the most simple lipopolysaccharides found on the surface of living bacter