Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Hiroaki Yagyu"'
Autor:
Rikako Nakajima, Daisuke Sato, Ichirota Togashi, Hiroto Idesawa, Jun Ito, Kei Ito, Masanao Fujii, Hiroaki Yagyu
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2024)
An 89-year-old woman presented with a 6-year history of occasional episodes of impaired consciousness that were relieved by ingestion of a snack. Three months before presenting to our hospital, she had been hospitalized in a local hospital with subdu
Externí odkaz:
https://doaj.org/article/64d3d2cd70ac4881b8d942ea8e77825b
Autor:
Rikako Nakajima, Hiroto Idesawa, Daisuke Sato, Jun Ito, Kei Ito, Masanao Fujii, Takamichi Suzuki, Tomoaki Furuta, Hitomi Kawai, Norio Takayashiki, Masanao Kurata, Hiroaki Yagyu
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2023)
Unawareness of postprandial hypoglycemia for 5 years was identified in a 66-year-old man at a local clinic. The patient was referred to our hospital because of this first awareness of hypoglycemia (i.e. lightheadedness and impaired consciousness) dev
Externí odkaz:
https://doaj.org/article/6e22ec18a28b4c5882cb15b78ff70b0a
Autor:
Hiroaki Yagyu, Hitoshi Shimano
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 9, Pp 1472-1488 (2022)
Abstract Cardiovascular (CV) disease is the most alarming complication of diabetes mellitus (DM), and a strategy aiming at cardiovascular event prevention in diabetes mellitus has long been debated. Large landmark clinical trials have shown cardiovas
Externí odkaz:
https://doaj.org/article/4a5461890ce94736b11e08d294b796db
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 9, Pp 1567-1576 (2022)
Abstract Aims/Introduction The importance of low‐density lipoprotein cholesterol (LDL‐C) in the primary prevention of cardiovascular disease has recently been reported in the population aged ≥75 years with hypercholesterolemia. Therefore, the c
Externí odkaz:
https://doaj.org/article/330e54d1f95a45ad8b8cd5a7f1c2fc2d
Autor:
Kei Ito, Jun Ito, Yuki Yamamoto, Rikako Nakajima, Masanao Fujii, Yukino Katakura, Aiko Muramatsu, Norio Takayashiki, Kazuhiro Toyama, Mineo Kurokawa, Hiroaki Yagyu
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2021)
A 61-year-old man developed central diabetes insipidus caused by mixed histiocytosis (MH) representing Langerhans cell histiocytosis overlapping with Erdheim–Chester disease. Bone, skin, vascular, and retroperitoneal involvements were also observed
Externí odkaz:
https://doaj.org/article/0b38127197264b718adc9b17e7e2e88d
Autor:
Yukiko Mikami, Yasushi Takai, Mana Obata-Yasuoka, Ryo Kumagai, Hiroaki Yagyu, Kosuke Shigematsu, Haipeng Huang, Nozomi Uemura, Mamiko Shinsaka, Masahiro Saitoh, Kazunori Baba, Hiroyuki Seki
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-4 (2019)
Abstract Background 17α-Hydroxylase deficiency is a recessively inherited autosomal disease caused by mutations in the CYP17A1 gene. It is a rare disease and accounts for approximately 1% of congenital adrenal cortex hyperplasias. Inhibition of 17α
Externí odkaz:
https://doaj.org/article/32eab58559e14765bd731da6e5f6c01b
Autor:
Ryo Kumagai, Aiko Muramatsu, Masanao Fujii, Yukino Katakura, Kei Ito, Keiko Fujie, Yoshio Nakata, Koichi Hashimoto, Hiroaki Yagyu
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 3, Pp 851-856 (2019)
Abstract Aims/Introduction Flash and continuous glucose monitoring systems are becoming prevalent in clinical practice. We directly compared a flash glucose monitoring system (FreeStyle Libre Pro [FSL‐Pro]) with a continuous glucose monitoring syst
Externí odkaz:
https://doaj.org/article/f471e50b50da4652a10825784c10f1f6
Autor:
Shuichi Nagashima, Hiroaki Yagyu, Ryuichi Tozawa, Fumiko Tazoe, Manabu Takahashi, Tetsuya Kitamine, Daisuke Yamamuro, Kent Sakai, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Akira Honda, Shun Ishibashi
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 5, Pp 998-1005 (2015)
Squalene synthase (SS) catalyzes the biosynthesis of squalene, the first specific intermediate in the cholesterol biosynthetic pathway. To test the feasibility of lowering plasma cholesterol by inhibiting hepatic SS, we generated mice in which SS is
Externí odkaz:
https://doaj.org/article/7b48d2ba7b554bd8aaf864108108d737
Autor:
Motohiro Sekiya, Daisuke Yamamuro, Taichi Ohshiro, Akira Honda, Manabu Takahashi, Masayoshi Kumagai, Kent Sakai, Shuichi Nagashima, Hiroshi Tomoda, Masaki Igarashi, Hiroaki Okazaki, Hiroaki Yagyu, Jun-ichi Osuga, Shun Ishibashi
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2082-2092 (2014)
An excess of cholesterol and/or oxysterols induces apoptosis in macrophages, contributing to the development of advanced atherosclerotic lesions. In foam cells, these sterols are stored in esterified forms, which are hydrolyzed by two enzymes: neutra
Externí odkaz:
https://doaj.org/article/8b2678c6d9294aa8b1e9b627bef59173
Autor:
Manabu Takahashi, Hiroaki Yagyu, Fumiko Tazoe, Shuichi Nagashima, Taichi Ohshiro, Kenta Okada, Jun-ichi Osuga, Ira J. Goldberg, Shun Ishibashi
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 4, Pp 1124-1134 (2013)
The role of macrophage lipoprotein lipase (LpL) in the development of atherosclerosis and adiposity was examined in macrophage LpL knockout (MLpLKO) mice. MLpLKO mice were generated using cre-loxP gene targeting. Loss of LpL in macrophages did not al
Externí odkaz:
https://doaj.org/article/c9c7e93472544de980ca2577a50f5a74