Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hiroaki Tsubokura"'
Autor:
Yoji Hisamatsu, Hiromi Murata, Hiroaki Tsubokura, Yoshiko Hashimoto, Masaaki Kitada, Susumu Tanaka, Hidetaka Okada
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 2111-2123 (2021)
Cyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4). Matrix metalloproteases (MMPs) and tissue
Externí odkaz:
https://doaj.org/article/81166cce2b954073801cddca84915a54
Autor:
Akemi Nishigaki, Hiroaki Tsubokura, Mitsuaki Ishida, Yoshiko Hashimoto, Aya Yoshida, Yoji Hisamatsu, Tomoko Tsuzuki‐Nakao, Hiromi Murata, Hidetaka Okada
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose N‐myc downstream‐regulated gene 1 (NDRG1) is expressed in various human tissues and plays a role in regulating cellular proliferation, angiogenesis, and hypoxia sensing. However, the role of NDRG1 in the ovary remains poorly unde
Externí odkaz:
https://doaj.org/article/063391346ab647a69ef50f7b68332f0c
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Background Ovarian function is closely related to the degree of vascular network development surrounding the ovary. Maternal aging‐related construction defects in this vascular network can cause ovarian hypoxia, which impedes oocyte nutrie
Externí odkaz:
https://doaj.org/article/8cf3ebf08cc34cffa9880eeee89f05a2
Autor:
Akemi Nishigaki, Takeharu Kido, Naoko Kida, Maiko Kakita‐Kobayashi, Hiroaki Tsubokura, Yoji Hisamatsu, Hidetaka Okada
Publikováno v:
Reproductive Medicine and Biology, Vol 19, Iss 2, Pp 189-197 (2020)
Abstract Purpose Resveratrol is a well‐known potent activator of sirtuin‐1 (SIRT1). We investigated the direct effects of hypoxia and resveratrol on SIRT1/ peroxisome proliferator‐activated receptor‐gamma coactivator 1α (PGC‐1α) pathways,
Externí odkaz:
https://doaj.org/article/db9fb0051ebf440b86bcfc05d0033395
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Abstract Background Generally, ovarian hyperstimulation syndrome develops after superovulation caused by ovulation-inducing drugs in infertile patients. However, ovarian hyperstimulation syndrome associated with natural pregnancy is rare, and most ca
Externí odkaz:
https://doaj.org/article/84774f8d6cb7428ba7a2f91dc93a8d45
Autor:
Takeharu Kido, Hiromi Murata, Akemi Nishigaki, Hiroaki Tsubokura, Shinnosuke Komiya, Naoko Kida, Maiko Kakita-Kobayashi, Yoji Hisamatsu, Tomoko Tsuzuki, Yoshiko Hashimoto, Hidetaka Okada
Publikováno v:
Heliyon, Vol 6, Iss 6, Pp e03985- (2020)
Aim: The study aimed to elucidate the glycolytic metabolism of human endometrial stromal cells (hESCs) in hypoxic environment. Main methods: The hESCs were cultured in hypoxic environment, and their metabolic pathways were analyzed using metabolomics
Externí odkaz:
https://doaj.org/article/6dd5fb80c4e64558900deeb59ae9d4aa
Autor:
Yoshiko Hashimoto, Yoji Hisamatsu, Susumu Tanaka, Hiromi Murata, Hiroaki Tsubokura, Masaaki Kitada, Hidetaka Okada
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 146, Pp 2111-2123 (2021)
Current Issues in Molecular Biology; Volume 43; Issue 3; Pages: 2111-2123
Current Issues in Molecular Biology; Volume 43; Issue 3; Pages: 2111-2123
Cyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4). Matrix metalloproteases (MMPs) and tissue
Autor:
Hiroaki, Tsubokura, Mitsuaki, Ishida, Akemi, Nishigaki, Takuya, Yokoe, Shinnosuke, Komiya, Yusuke, Butsuhara, Aya, Yoshida, Yoji, Hisamatsu, Yoshiko, Hashimoto, Tomoko, Tsuzuki-Nakao, Hiromi, Murata, Koji, Tsuta, Hidetaka, Okada
Publikováno v:
Molecular Medicine Reports. 27
Preeclampsia, characterized by high blood pressure and proteinuria during pregnancy, causes serious complications in both the mother and the fetus. Although there have been several studies on the causes of preeclampsia, the detailed mechanism of this
Autor:
Masaaki Kitada, Hidetaka Okada, Susumu Tanaka, Yoji Hisamatsu, Yoshiko Hashimoto, Hiromi Murata, Hiroaki Tsubokura
Publikováno v:
Molecular Human Reproduction. 27
Uterine natural killer cells are regulated via surface inhibitory receptors for IL15 and galectin-9 (LGALS9) secreted by endometrial stromal cells (ESCs). However, the mechanism that regulates LGALS9 mRNA levels in ESCs is unclear. The aim of this st
Autor:
Akemi Nishigaki, Hiroaki Tsubokura, Mitsuaki Ishida, Yoshiko Hashimoto, Aya Yoshida, Yoji Hisamatsu, Tomoko Tsuzuki‐Nakao, Hiromi Murata, Hidetaka Okada
Publikováno v:
Reproductive medicine and biology. 21(1)
N-myc downstream-regulated gene 1 (NDRG1) is expressed in various human tissues and plays a role in regulating cellular proliferation, angiogenesis, and hypoxia sensing. However, the role of NDRG1 in the ovary remains poorly understood. Therefore, we