Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hiroaki Shioya"'
Autor:
Shinichi Tokunaga, Makoto Higuchi, Hiroaki Shioya, Hironobu Saito, Hisao Oguchi, Yukinori Kawaharo, Makoto Miyasaka, Seiichi Furuta, Kunihiko Yazaki, Masuo Tokoo
Publikováno v:
Drug Investigation. 7:161-165
Since the discovery of captopril, the first angiotensin converting enzyme (ACE) inhibitor, by Ondetti et al. in 1977, many ACE inhibitors have been developed (Hui et al. 1991; Ondetti et al. 1977). However, almost all ACE inhibitors currently availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d310cd8f40e86c9c88b44dccb3163a8
https://doi.org/10.1007/bf03258469
https://doi.org/10.1007/bf03258469
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 568:309-314
A method of determining a new angiotensin-converting enzyme inhibitor (CS-622) and its active metabolite (RS-5139) in plasma by inhibitor-binding assay has been developed using high-performance liquid chromatography. The assay is based on the princip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd93f5290672484fd8df882015edee64
https://doi.org/10.1016/0378-4347(91)80168-c
https://doi.org/10.1016/0378-4347(91)80168-c
Pharmacokinetics of temocapril and enalapril in patients with various degrees of renal insufficiency
Autor:
Hiroaki Shioya, Makoto Miyasaka, Kiyotaka Sato, Seiichi Furuta, Kazuhiko Hora, Toshihiko Koiwai, Shinichi Tokunaga, Hisao Oguchi, Takahiro Yoshie
Publikováno v:
Clinical pharmacokinetics. 24(5)
Temocapril is a novel ACE inhibitor that is cleared via dual excretion routes in humans. Borderline or mildly hypertensive patients with normal renal function [group 1, creatinine clearance (CLcr) >70 ml/min (4.2 L/h), n = 12], moderate renal impairm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea35d1ff0f0d03dc53bd2dae4d7e757b
https://pubmed.ncbi.nlm.nih.gov/8504625
https://pubmed.ncbi.nlm.nih.gov/8504625
Publikováno v:
Biomedical chromatography : BMC. 6(2)
The method for the simultaneous determination of angiotensin-converting enzyme (ACE) inhibitor enalapril and its active metabolite enalaprilat in plasma and urine was developed by gas chromatography/mass spectrometry. Enalapril and enalaprilat in pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67a31dbfe02b7606120de9ea78d101b
https://pubmed.ncbi.nlm.nih.gov/1322206
https://pubmed.ncbi.nlm.nih.gov/1322206
Autor:
Hidekuni Takahagi, Hiroaki Shioya, Yukio Shimada, Yukinori Kawahara, Akihiko Nakagawa, Kan-ichi Nakamura, Hideo Naganuma, Yukimi Tanishima
Publikováno v:
Drug Metabolism and Pharmacokinetics. 2:113-121
A GC/MS method for the determination of CS-570, a chemically stable prostacyclin analogue, was developed. This assay method was applied to study a disposition of CS-570 in dogs after a single or continuous intravenous administration. An acidified pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d90b62b7439aa7233a9f1f79d9c2a649
https://doi.org/10.2133/dmpk.2.113
https://doi.org/10.2133/dmpk.2.113
Publikováno v:
Chemical and Pharmaceutical Bulletin. 30:202-205
In order to develop specific and sensitive immunoassays, new carboxylated derivatives of androstenedione, 11β-hydroxyandrostenedione, adrenosterone, progesterone, 17α-hydroxyprogesterone, corticosterone, 11-deoxycorticosterone and 21-deoxycortisol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8bbd1aea31b9e324285c79758a5241
https://doi.org/10.1248/cpb.30.202
https://doi.org/10.1248/cpb.30.202
Publikováno v:
Chemical and Pharmaceutical Bulletin. 33:1049-1054
On prepare les deux epimeres 20α et 20β du glucuronide-3 de l'acide trihydroxy-3α,17α,20α pregnane-5β oique-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c0a642ba9702ff1ed303c949fcf152
https://doi.org/10.1248/cpb.33.1049
https://doi.org/10.1248/cpb.33.1049
Publikováno v:
Chemical and Pharmaceutical Bulletin. 32:1891-1897
The N-succinimidyl esters of various glycine-conjugated bile acid 3-hemisuccinates and 3-hemiglutarates have been prepared for use in immunoassay. Unconjugated bile acids were condensed with p-nitrophenol to form the activated esters. Subsequent reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19992a7df9fb818be31fb037f32b6f5b
https://doi.org/10.1248/cpb.32.1891
https://doi.org/10.1248/cpb.32.1891
Publikováno v:
Journal of chromatography. 496(1)
A sensitive and specific gas chromatographic-mass spectrometric method for the simultaneous determination of angiotensin-converting enzyme inhibitor (I, CS-622) and its active desethyl metabolite (II, RS-5139) in plasma and urine was developed. Compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5ac7c1163e7fc31ae1cb18fb71c3ec
https://pubmed.ncbi.nlm.nih.gov/2592507
https://pubmed.ncbi.nlm.nih.gov/2592507